Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYN1
  • Mouse genes Syn1
  • Rat genes Syn1
  • Zfish genes syn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	Syn1	IPI	RGD:3614	Rat	PMID:10567243|RGD:7205635
Molecular Function	GO:0042802	identical protein binding	Syn1	IPI	PR:O88935	Mouse	PMID:15071120
Molecular Function	GO:0005515	protein binding	SYN1	IPI	UniProtKB:Q92777	Human	PMID:23406870
Molecular Function	GO:0005515	protein binding	Syn1	IPI	UniProtKB:O54960	Rat	PMID:11867766|RGD:8553593
Molecular Function	GO:0005515	protein binding	Syn1	IPI	RGD:620053	Rat	PMID:17088214|RGD:5684965
Molecular Function	GO:0005515	protein binding	syn1	IPI	UniProtKB:A2A121	Zfish	PMID:20097902|ZFIN:ZDB-PUB-100126-16
Molecular Function	GO:0019901	protein kinase binding	Syn1	IPI	UniProtKB:Q5S007	Mouse	MGI:MGI:4941068|PMID:21307259
Cellular Component	GO:0030424	axon	Syn1	IDA		Mouse	PMID:17634368
Cellular Component	GO:0030424	axon	Syn1	IDA		Mouse	PMID:15255972
Cellular Component	GO:0044297	cell body	Syn1	IDA		Mouse	PMID:17634368
Cellular Component	GO:0005856	cytoskeleton	SYN1	IDA		Human	PMID:24327345
Cellular Component	GO:0005829	cytosol	Syn1	IDA		Rat	PMID:10340764|RGD:4892571
Cellular Component	GO:0030425	dendrite	Syn1	IDA		Mouse	PMID:17634368
Cellular Component	GO:0030425	dendrite	Syn1	IDA		Rat	PMID:1419001|RGD:68238
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Syn1	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Syn1	IDA		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Syn1	IDA		Rat	PMID:31959215|RGD:155230771
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Syn1	IDA		Rat	PMID:6404912|RGD:13702282
Cellular Component	GO:0043229	intracellular organelle	Syn1	IDA		Rat	PMID:10340764|RGD:4892571
Cellular Component	GO:0043209	myelin sheath	Syn1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0014069	postsynaptic density	Syn1	IDA		Mouse	PMID:17114649
Cellular Component	GO:0098793	presynapse	SYN1	IDA		Human	PMID:21441247
Cellular Component	GO:0098793	presynapse	Syn1	IDA		Mouse	PMID:27759003
Cellular Component	GO:0048786	presynaptic active zone	Syn1	IDA		Mouse	PMID:16621800
Cellular Component	GO:0048786	presynaptic active zone	Syn1	IDA		Rat	PMID:21119615|RGD:8554416
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Syn1	IDA		Mouse	PMID:7902212
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Syn1	IMP		Mouse	PMID:7902212
Cellular Component	GO:0045202	synapse	Syn1	IDA		Mouse	PMID:17018287
Cellular Component	GO:0045202	synapse	Syn1	IDA		Mouse	PMID:16025111
Cellular Component	GO:0045202	synapse	Syn1	IDA		Mouse	PMID:15479642
Cellular Component	GO:0045202	synapse	Syn1	IDA		Mouse	PMID:16818724
Cellular Component	GO:0045202	synapse	Syn1	IDA		Mouse	PMID:15071120
Cellular Component	GO:0045202	synapse	Syn1	IDA		Mouse	PMID:14622577
Cellular Component	GO:0045202	synapse	Syn1	IDA		Rat	PMID:24613359|RGD:10047247
Cellular Component	GO:0008021	synaptic vesicle	Syn1	IDA		Rat	PMID:11867766|RGD:8553593
Cellular Component	GO:0008021	synaptic vesicle	Syn1	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Syn1	IDA		Mouse	PMID:15071120
Cellular Component	GO:0030672	synaptic vesicle membrane	Syn1	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0000795	synaptonemal complex	Syn1	IDA		Mouse	PMID:14736746
Cellular Component	GO:0043195	terminal bouton	Syn1	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0048666	neuron development	Syn1	IEP		Rat	PMID:27228907|RGD:13542092
Biological Process	GO:0007269	neurotransmitter secretion	Syn1	IGI	MGI:MGI:103020	Mouse	PMID:7777057
Biological Process	GO:0007269	neurotransmitter secretion	Syn1	IMP	MGI:MGI:1857250	Mouse	PMID:7777057
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Syn1	IDA		Mouse	PMID:8794863
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	Syn1	IMP		Mouse	PMID:8794863
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	SYN1	IMP		Human	PMID:21441247
Biological Process	GO:0050808	synapse organization	Syn1	IMP		Rat	PMID:22045728|RGD:13593565
Biological Process	GO:0097091	synaptic vesicle clustering	Syn1	IMP		Mouse	MGI:MGI:76610|PMID:7568108
Biological Process	GO:0099504	synaptic vesicle cycle	Syn1	IMP		Mouse	PMID:7902212
Biological Process	GO:0099504	synaptic vesicle cycle	Syn1	IDA		Mouse	PMID:7902212

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern