Comparative GO Graph (mouse, human, rat)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Rdx

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes RDX
- Mouse genes Rdx
- Rat genes Rdx
- Zfish genes
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rdx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	RDX	IDA		Human	PMID:17825285
Molecular Function	GO:0003779	actin binding	Rdx	IDA		Rat	PMID:2500445\|RGD:8693627
Molecular Function	GO:0051117	ATPase binding	RDX	IPI	UniProtKB:Q92887	Human	PMID:17825285
Molecular Function	GO:0045296	cadherin binding	RDX	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	RDX	IPI	UniProtKB:Q9EP53	Human	PMID:10806479
Molecular Function	GO:0005515	protein binding	RDX	IPI	UniProtKB:P05107	Human	PMID:17321526
Molecular Function	GO:0005515	protein binding	RDX	IPI	UniProtKB:Q9H270	Human	PMID:21148287
Molecular Function	GO:0005515	protein binding	RDX	IPI	UniProtKB:P15311	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	RDX	IPI	UniProtKB:P15311	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RDX	IPI	UniProtKB:P15311	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	RDX	IPI	UniProtKB:Q8IZU9	Human	PMID:34799561
Molecular Function	GO:0005515	protein binding	Rdx	IPI	UniProtKB:P35330	Mouse	MGI:MGI:3693394\|PMID:12554651
Molecular Function	GO:0005515	protein binding	Rdx	IPI	UniProtKB:P13838\|UniProtKB:P15379\|UniProtKB:P35330	Mouse	MGI:MGI:6115186\|PMID:9472040
Molecular Function	GO:0005515	protein binding	Rdx	IPI	UniProtKB:Q96A23\|UniProtKB:Q99829	Mouse	MGI:MGI:5294308\|PMID:12522145
Molecular Function	GO:0005515	protein binding	Rdx	IPI	UniProtKB:O14745\|UniProtKB:P35330\|UniProtKB:Q15599	Mouse	MGI:MGI:5926357\|PMID:16615918
Molecular Function	GO:0005515	protein binding	Rdx	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0005515	protein binding	Rdx	IPI	PR:Q8VI47	Mouse	PMID:12068294
Molecular Function	GO:0005515	protein binding	Rdx	IPI	PR:P35330	Mouse	PMID:12068294
Molecular Function	GO:0005515	protein binding	Rdx	IPI	PR:P15702	Mouse	PMID:12068294
Molecular Function	GO:0005515	protein binding	Rdx	IPI	UniProtKB:P15311	Rat	PMID:7844168\|RGD:152025508
Molecular Function	GO:0019904	protein domain specific binding	Rdx	IPI	UniProtKB:O95398	Mouse	MGI:MGI:5645204\|PMID:21047789
Molecular Function	GO:0051018	protein kinase A binding	Rdx	IMP		Rat	PMID:21047789\|RGD:10054076
Molecular Function	GO:0003723	RNA binding	RDX	HDA		Human	PMID:22658674
Cellular Component	GO:0005912	adherens junction	Rdx	IDA		Rat	PMID:2500445\|RGD:8693627
Cellular Component	GO:0045177	apical part of cell	Rdx	IDA		Mouse	PMID:9890997
Cellular Component	GO:0016324	apical plasma membrane	RDX	IDA		Human	PMID:17825285
Cellular Component	GO:0071944	cell periphery	RDX	IDA		Human	PMID:22291017
Cellular Component	GO:0051286	cell tip	Rdx	IDA		Rat	PMID:17061246\|RGD:7207800
Cellular Component	GO:0032154	cleavage furrow	Rdx	IDA		Rat	PMID:1707055\|RGD:8693619
Cellular Component	GO:0030864	cortical actin cytoskeleton	Rdx	IDA		Mouse	MGI:MGI:5645204\|PMID:21047789
Cellular Component	GO:0030864	cortical actin cytoskeleton	Rdx	IDA		Rat	PMID:21047789\|RGD:10054076
Cellular Component	GO:0070062	extracellular exosome	RDX	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RDX	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	RDX	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	RDX	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	RDX	HDA		Human	PMID:16502470
Cellular Component	GO:0030175	filopodium	Rdx	IDA		Mouse	MGI:MGI:5645204\|PMID:21047789
Cellular Component	GO:0030175	filopodium	Rdx	IDA		Mouse	PMID:9563848
Cellular Component	GO:0030175	filopodium	Rdx	IDA		Rat	PMID:21047789\|RGD:10054076
Cellular Component	GO:0005925	focal adhesion	RDX	IDA		Human	PMID:21282464
Cellular Component	GO:0005925	focal adhesion	RDX	HDA		Human	PMID:21423176
Cellular Component	GO:0030027	lamellipodium	Rdx	IDA		Mouse	MGI:MGI:5645204\|PMID:21047789
Cellular Component	GO:0030027	lamellipodium	Rdx	IDA		Mouse	PMID:9563848
Cellular Component	GO:0030027	lamellipodium	Rdx	IDA		Rat	PMID:21047789\|RGD:10054076
Cellular Component	GO:0005902	microvillus	Rdx	IDA		Mouse	MGI:MGI:6115186\|PMID:9472040
Cellular Component	GO:0005902	microvillus	Rdx	IDA		Mouse	MGI:MGI:5645204\|PMID:21047789
Cellular Component	GO:0005902	microvillus	Rdx	IDA		Mouse	PMID:12068294
Cellular Component	GO:0005902	microvillus	Rdx	IDA		Mouse	PMID:15093731
Cellular Component	GO:0005902	microvillus	Rdx	IDA		Rat	PMID:11438984\|RGD:2316843
Cellular Component	GO:0005902	microvillus	Rdx	IDA		Rat	PMID:21047789\|RGD:10054076
Cellular Component	GO:0030496	midbody	Rdx	IDA		Rat	PMID:1707055\|RGD:8693619
Cellular Component	GO:0043209	myelin sheath	Rdx	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0005886	plasma membrane	RDX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Rdx	IDA		Mouse	MGI:MGI:5645204\|PMID:21047789
Cellular Component	GO:0005886	plasma membrane	Rdx	IDA		Rat	PMID:21047789\|RGD:10054076
Cellular Component	GO:0005886	plasma membrane	Rdx	IDA		Rat	PMID:18700187\|RGD:2316839
Cellular Component	GO:0001726	ruffle	Rdx	IDA		Mouse	PMID:9563848
Cellular Component	GO:0032420	stereocilium	Rdx	IDA		Mouse	PMID:17021174
Cellular Component	GO:0030315	T-tubule	Rdx	IDA		Rat	PMID:19028724\|RGD:7207798
Biological Process	GO:0045176	apical protein localization	Rdx	IMP	MGI:MGI:2671151	Mouse	PMID:12068294
Biological Process	GO:0045176	apical protein localization	Rdx	IMP		Rat	PMID:16952556\|RGD:2316840
Biological Process	GO:0051016	barbed-end actin filament capping	Rdx	IDA		Rat	PMID:2500445\|RGD:8693627
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Rdx	IEP		Rat	PMID:8647942\|RGD:8693616
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	Rdx	IMP		Mouse	MGI:MGI:5645204\|PMID:21047789
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	Rdx	IMP		Rat	PMID:21047789\|RGD:10054076
Biological Process	GO:0061028	establishment of endothelial barrier	RDX	IGI	UniProtKB:P15311\|UniProtKB:P26038	Human	PMID:23264465
Biological Process	GO:0045184	establishment of protein localization	Rdx	IMP		Mouse	MGI:MGI:5645204\|PMID:21047789
Biological Process	GO:0061951	establishment of protein localization to plasma membrane	Rdx	IMP		Rat	PMID:21047789\|RGD:10054076
Biological Process	GO:0030033	microvillus assembly	Rdx	IMP	MGI:MGI:2671151	Mouse	PMID:12068294
Biological Process	GO:1903392	negative regulation of adherens junction organization	RDX	IMP		Human	PMID:22467863
Biological Process	GO:0045792	negative regulation of cell size	RDX	IMP		Human	PMID:22467863
Biological Process	GO:0034260	negative regulation of GTPase activity	RDX	IMP		Human	PMID:22467863
Biological Process	GO:0034111	negative regulation of homotypic cell-cell adhesion	RDX	IMP		Human	PMID:22467863
Biological Process	GO:0030335	positive regulation of cell migration	RDX	IMP		Human	PMID:22467863
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	RDX	IGI	UniProtKB:P15311\|UniProtKB:P26038	Human	PMID:21148287
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	Rdx	IMP		Mouse	MGI:MGI:5645204\|PMID:21047789
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	Rdx	IMP		Rat	PMID:21047789\|RGD:10054076
Biological Process	GO:0010628	positive regulation of gene expression	RDX	IGI	UniProtKB:Q96S97	Human	PMID:23264465
Biological Process	GO:0045732	positive regulation of protein catabolic process	RDX	IGI	UniProtKB:P15311\|UniProtKB:P26038	Human	PMID:21148287
Biological Process	GO:1902966	positive regulation of protein localization to early endosome	RDX	IGI	UniProtKB:P15311\|UniProtKB:P26038	Human	PMID:21148287
Biological Process	GO:0010737	protein kinase A signaling	Rdx	IMP		Rat	PMID:21047789\|RGD:10054076
Biological Process	GO:0072659	protein localization to plasma membrane	RDX	IMP		Human	PMID:17825285
Biological Process	GO:0032231	regulation of actin filament bundle assembly	RDX	IMP		Human	PMID:22467863
Biological Process	GO:0008360	regulation of cell shape	RDX	IMP		Human	PMID:22467863
Biological Process	GO:0008361	regulation of cell size	RDX	IGI	UniProtKB:P15498,UniProtKB:P52735,UniProtKB:Q9UKW4	Human	PMID:22467863
Biological Process	GO:0008361	regulation of cell size	RDX	IGI	UniProtKB:P63000	Human	PMID:22467863
Biological Process	GO:0043087	regulation of GTPase activity	RDX	IGI	UniProtKB:P15498,UniProtKB:P52735,UniProtKB:Q9UKW4	Human	PMID:22467863
Biological Process	GO:1902115	regulation of organelle assembly	RDX	IGI	UniProtKB:P15311\|UniProtKB:P26038	Human	PMID:21148287
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	Rdx	IDA		Mouse	PMID:25891999
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	Rdx	IMP		Mouse	PMID:25891999
Biological Process	GO:0032487	regulation of Rap protein signal transduction	Rdx	IMP		Rat	PMID:21047789\|RGD:10054076
Biological Process	GO:1900027	regulation of ruffle assembly	RDX	IMP		Human	PMID:22467863

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.