| GO term: | ruffle |
| Synonym: | membrane ruffle |
| GO id: | GO:0001726 |
| Definition: | Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. |
| Number of paths to term: | 4 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partcell leading edgeAPC-IQGAP complexAPC-IQGAP1-Cdc42 complexAPC-IQGAP1-CLIP-170 complexAPC-IQGAP1-Rac1 complexCSK-GAP-A.p62 complexlamellipodium +leading edge membrane +ruffle [GO:0001726] (97 genes, 103 annotations)ruffle membranecellular_componentcellcell partcell projectionblebbrush border +cell haircell projection part +cilium +cytonemefilopodium +glial cell projection +haustorium +invadopodium +lamellipodium +macropinocytic cup +mating projection +microspikemicrovillus +muscle cell projection +neuron projection +oral apparatus +pilus +plant cell papilla +pollen tube +pseudopodium +rhabdomere +root hair +ruffle [GO:0001726] (97 genes, 103 annotations)ruffle membraneuropod +cellular_componentcell partcell leading edgeAPC-IQGAP complexAPC-IQGAP1-Cdc42 complexAPC-IQGAP1-CLIP-170 complexAPC-IQGAP1-Rac1 complexCSK-GAP-A.p62 complexlamellipodium +leading edge membrane +ruffle [GO:0001726] (97 genes, 103 annotations)ruffle membranecellular_componentcell partcell projectionblebbrush border +cell haircell projection part +cilium +cytonemefilopodium +glial cell projection +haustorium +invadopodium +lamellipodium +macropinocytic cup +mating projection +microspikemicrovillus +muscle cell projection +neuron projection +oral apparatus +pilus +plant cell papilla +pollen tube +pseudopodium +rhabdomere +root hair +ruffle [GO:0001726] (97 genes, 103 annotations)ruffle membraneuropod +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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