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Gene Ontology Browser
Term Detail
GO term:ruffle
Synonym: membrane ruffle
GO id:GO:0001726
Definition:Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell leading edge
                                        part-ofAPC-IQGAP complex
                                        part-ofAPC-IQGAP1-Cdc42 complex
                                        part-ofAPC-IQGAP1-CLIP-170 complex
                                        part-ofAPC-IQGAP1-Rac1 complex
                                        part-ofCSK-GAP-A.p62 complex
                                        part-oflamellipodium +
                                        part-ofleading edge membrane +
                                        part-ofruffle [GO:0001726] (107 genes, 117 annotations)
                                                part-ofruffle membrane


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection
                                        is-aarchaeal-type flagellum
                                        is-abacterial-type flagellum +
                                        is-ableb
                                        is-abrush border +
                                        is-acell hair
                                        part-ofcell projection part +
                                        is-acilium +
                                        is-acytoneme
                                        is-adendritic cell dendrite
                                        is-afilopodium +
                                        is-aglial cell projection +
                                        is-ahaustorium +
                                        is-ainvadopodium +
                                        is-alamellipodium +
                                        is-amacropinocytic cup +
                                        is-amating projection +
                                        is-amicrospike
                                        is-amicrovillus +
                                        is-amuscle cell projection +
                                        is-aneuron projection +
                                        is-aoral apparatus +
                                        is-apilus +
                                        is-aplant cell papilla +
                                        is-apollen tube +
                                        is-apseudopodium +
                                        is-arhabdomere +
                                        is-aroot hair +
                                        is-aruffle [GO:0001726] (107 genes, 117 annotations)
                                                part-ofruffle membrane
                                        is-auropod +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell leading edge
                                part-ofAPC-IQGAP complex
                                part-ofAPC-IQGAP1-Cdc42 complex
                                part-ofAPC-IQGAP1-CLIP-170 complex
                                part-ofAPC-IQGAP1-Rac1 complex
                                part-ofCSK-GAP-A.p62 complex
                                part-oflamellipodium +
                                part-ofleading edge membrane +
                                part-ofruffle [GO:0001726] (107 genes, 117 annotations)
                                        part-ofruffle membrane


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection
                                is-aarchaeal-type flagellum
                                is-abacterial-type flagellum +
                                is-ableb
                                is-abrush border +
                                is-acell hair
                                part-ofcell projection part +
                                is-acilium +
                                is-acytoneme
                                is-adendritic cell dendrite
                                is-afilopodium +
                                is-aglial cell projection +
                                is-ahaustorium +
                                is-ainvadopodium +
                                is-alamellipodium +
                                is-amacropinocytic cup +
                                is-amating projection +
                                is-amicrospike
                                is-amicrovillus +
                                is-amuscle cell projection +
                                is-aneuron projection +
                                is-aoral apparatus +
                                is-apilus +
                                is-aplant cell papilla +
                                is-apollen tube +
                                is-apseudopodium +
                                is-arhabdomere +
                                is-aroot hair +
                                is-aruffle [GO:0001726] (107 genes, 117 annotations)
                                        part-ofruffle membrane
                                is-auropod +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory