Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRSS12
  • Mouse genes Prss12
  • Rat genes Prss12
  • Zfish genes prss12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prss12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008233	peptidase activity	Prss12	IMP	MGI:MGI:3804289	Mouse	PMID:17586728
Molecular Function	GO:0008233	peptidase activity	Prss12	IMP	MGI:MGI:3804290	Mouse	PMID:18230682
Molecular Function	GO:0004252	serine-type endopeptidase activity	Prss12	IDA		Mouse	PMID:17223089
Cellular Component	GO:0030424	axon	Prss12	IDA		Mouse	MGI:MGI:3831737|PMID:18272678
Cellular Component	GO:0031410	cytoplasmic vesicle	Prss12	IDA		Mouse	PMID:17223089
Cellular Component	GO:0030425	dendrite	Prss12	IDA		Mouse	PMID:17223089
Cellular Component	GO:0005886	plasma membrane	Prss12	IDA		Mouse	MGI:MGI:3831737|PMID:18272678
Cellular Component	GO:0045202	synapse	Prss12	IDA		Mouse	PMID:18230682
Cellular Component	GO:0043083	synaptic cleft	Prss12	IDA		Mouse	PMID:18272678
Cellular Component	GO:0043195	terminal bouton	Prss12	IDA		Mouse	PMID:18272678
Biological Process	GO:0006887	exocytosis	Prss12	IDA		Mouse	MGI:MGI:3831737|PMID:18272678
Biological Process	GO:0006508	proteolysis	Prss12	IDA		Mouse	PMID:17223089
Biological Process	GO:0006508	proteolysis	Prss12	IMP	MGI:MGI:3804289	Mouse	PMID:17586728
Biological Process	GO:0006508	proteolysis	Prss12	IMP	MGI:MGI:3804290	Mouse	PMID:18230682
Biological Process	GO:0031638	zymogen activation	Prss12	IDA		Mouse	PMID:17223089

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern