Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU3F2
  • Mouse genes Pou3f2
  • Rat genes Pou3f2
  • Zfish genes pou3f2a,pou3f2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou3f2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Pou3f2	IDA		Mouse	MGI:MGI:5009531|PMID:18403418
Molecular Function	GO:0003677	DNA binding	Pou3f2	IDA		Mouse	PMID:12782656
Molecular Function	GO:0003677	DNA binding	Pou3f2	IDA		Mouse	PMID:15465489
Molecular Function	GO:0003677	DNA binding	Pou3f2	IDA		Rat	PMID:8276233|RGD:61700
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou3f2	IDA		Mouse	MGI:MGI:3056028|PMID:15465489
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou3f2	IDA		Rat	PMID:12637543|RGD:8554307
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou3f2	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou3f2	IDA		Rat	PMID:9196379|RGD:2290189
Molecular Function	GO:0071837	HMG box domain binding	Pou3f2	IDA		Rat	PMID:12637543|RGD:8554307
Molecular Function	GO:0042802	identical protein binding	POU3F2	IPI	UniProtKB:P20265	Human	PMID:11029584
Molecular Function	GO:0005515	protein binding	POU3F2	IPI	UniProtKB:P20226	Human	PMID:11029584
Molecular Function	GO:0005515	protein binding	POU3F2	IPI	UniProtKB:P23760	Human	PMID:11029584
Molecular Function	GO:0005515	protein binding	POU3F2	IPI	UniProtKB:P56693	Human	PMID:11029584
Molecular Function	GO:0005515	protein binding	POU3F2	IPI	UniProtKB:Q09472	Human	PMID:11029584
Molecular Function	GO:0005515	protein binding	Pou3f2	IPI	UniProtKB:P61372	Mouse	MGI:MGI:5825419|PMID:24643061
Molecular Function	GO:0005515	protein binding	Pou3f2	IPI	UniProtKB:P0C1G9	Rat	PMID:12637543|RGD:8554307
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pou3f2	IDA		Mouse	MGI:MGI:3056028|PMID:15465489
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou3f2	IDA		Mouse	PMID:17141158
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou3f2	IDA		Rat	PMID:9196379|RGD:2290189
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	POU3F2	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	POU3F2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Pou3f2	IDA		Mouse	PMID:12782656
Cellular Component	GO:0005634	nucleus	Pou3f2	IDA		Rat	PMID:9196379|RGD:2290189
Cellular Component	GO:0005667	transcription regulator complex	Pou3f2	IDA		Mouse	PMID:12782656
Biological Process	GO:0071310	cellular response to organic substance	Pou3f2	IDA		Mouse	PMID:18794345
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Pou3f2	IGI	MGI:MGI:102564	Mouse	PMID:12130536
Biological Process	GO:0001885	endothelial cell development	pou3f2b	IMP	ZFIN:ZDB-MRPHLNO-170601-3	Zfish	PMID:28323620
Biological Process	GO:0001885	endothelial cell development	pou3f2b	IMP	ZFIN:ZDB-MRPHLNO-100423-9	Zfish	PMID:28323620
Biological Process	GO:0008544	epidermis development	Pou3f2	IMP	MGI:MGI:1857996	Mouse	PMID:8543156
Biological Process	GO:0021897	forebrain astrocyte development	Pou3f2	IMP	MGI:MGI:1857996	Mouse	PMID:8543156
Biological Process	GO:0021869	forebrain ventricular zone progenitor cell division	Pou3f2	IGI	MGI:MGI:102564	Mouse	PMID:12130536
Biological Process	GO:0021979	hypothalamus cell differentiation	Pou3f2	IMP	MGI:MGI:1857996	Mouse	PMID:8543156
Biological Process	GO:0022011	myelination in peripheral nervous system	Pou3f2	IGI	MGI:MGI:101896	Mouse	PMID:12782656
Biological Process	GO:0010629	negative regulation of gene expression	Pou3f2	IMP		Mouse	MGI:MGI:5449484|PMID:23069940
Biological Process	GO:0007399	nervous system development	Pou3f2	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0061101	neuroendocrine cell differentiation	Pou3f2	IMP	MGI:MGI:1857996	Mouse	PMID:8543156
Biological Process	GO:0021985	neurohypophysis development	Pou3f2	IMP	MGI:MGI:1857996	Mouse	PMID:8543156
Biological Process	GO:0048666	neuron development	Pou3f2	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0030182	neuron differentiation	Pou3f2	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0030182	neuron differentiation	Pou3f2	IDA		Mouse	PMID:17141158
Biological Process	GO:0048663	neuron fate commitment	Pou3f2	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0048665	neuron fate specification	Pou3f2	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0008284	positive regulation of cell population proliferation	POU3F2	IDA		Human	PMID:15024079
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Pou3f2	IMP	MGI:MGI:1857996	Mouse	PMID:8543156
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou3f2	IDA		Mouse	MGI:MGI:3056028|PMID:15465489
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou3f2	IDA		Mouse	MGI:MGI:5009531|PMID:18403418
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou3f2	IGI	MGI:MGI:96919	Mouse	PMID:17141158
Biological Process	GO:0050770	regulation of axonogenesis	Pou3f2	IMP	MGI:MGI:1857996	Mouse	PMID:8543156
Biological Process	GO:0045595	regulation of cell differentiation	Pou3f2	IMP		Mouse	PMID:8593698
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pou3f2	IDA		Rat	PMID:9196379|RGD:2290189
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Pou3f2	IDA		Mouse	MGI:MGI:5897542|PMID:24243019
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Pou3f2	IDA		Mouse	PMID:15465489
Biological Process	GO:0014044	Schwann cell development	Pou3f2	IGI	MGI:MGI:101896	Mouse	PMID:12782656

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern