Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MMP7
  • Mouse genes Mmp7
  • Rat genes Mmp7
  • Zfish genes mmp20a,mmp30
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mmp7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	MMP7	IDA		Human	PMID:23845380
Molecular Function	GO:0008201	heparin binding	Mmp7	IDA		Rat	PMID:10660581|RGD:9685351
Molecular Function	GO:0008237	metallopeptidase activity	MMP7	IDA		Human	PMID:15297466
Molecular Function	GO:0008237	metallopeptidase activity	MMP7	IDA		Human	PMID:26482249
Molecular Function	GO:0008233	peptidase activity	Mmp7	IDA		Mouse	PMID:20056603
Molecular Function	GO:0008233	peptidase activity	Mmp7	IMP	MGI:MGI:1857932	Mouse	PMID:20056603
Molecular Function	GO:0005515	protein binding	MMP7	IPI	UniProtKB:P17931	Human	PMID:20812334
Cellular Component	GO:0009986	cell surface	Mmp7	IDA		Rat	PMID:10660581|RGD:9685351
Cellular Component	GO:0070062	extracellular exosome	MMP7	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Mmp7	IDA		Rat	PMID:23256367|RGD:9685354
Biological Process	GO:0007568	aging	Mmp7	IEP		Rat	PMID:17670906|RGD:9685345
Biological Process	GO:0002780	antibacterial peptide biosynthetic process	Mmp7	IMP		Mouse	PMID:20056603
Biological Process	GO:0002779	antibacterial peptide secretion	Mmp7	IMP		Mouse	PMID:11248802
Biological Process	GO:0071260	cellular response to mechanical stimulus	Mmp7	IEP		Rat	PMID:20054150|RGD:8547898
Biological Process	GO:0042742	defense response to bacterium	Mmp7	IMP		Mouse	PMID:11248802
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Mmp7	IMP		Mouse	PMID:11248802
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Mmp7	IMP		Mouse	PMID:11248802
Biological Process	GO:0044849	estrous cycle	Mmp7	IEP		Rat	PMID:10070364|RGD:9685349
Biological Process	GO:0060135	maternal process involved in female pregnancy	Mmp7	IEP		Rat	PMID:10645258|RGD:9685360
Biological Process	GO:0006509	membrane protein ectodomain proteolysis	MMP7	IMP		Human	PMID:23437250
Biological Process	GO:0031293	membrane protein intracellular domain proteolysis	MMP7	IMP		Human	PMID:23437250
Biological Process	GO:0030335	positive regulation of cell migration	MMP7	IDA		Human	PMID:23437250
Biological Process	GO:0006508	proteolysis	MMP7	IDA		Human	PMID:15297466
Biological Process	GO:0006508	proteolysis	MMP7	IDA		Human	PMID:26482249
Biological Process	GO:0006508	proteolysis	Mmp7	IMP	MGI:MGI:1857932	Mouse	PMID:20056603
Biological Process	GO:0006508	proteolysis	Mmp7	IDA		Mouse	PMID:20056603
Biological Process	GO:0042127	regulation of cell population proliferation	Mmp7	IGI	MGI:MGI:88039	Mouse	PMID:9037065
Biological Process	GO:0031667	response to nutrient levels	Mmp7	IEP		Rat	PMID:17670906|RGD:9685345
Biological Process	GO:0009410	response to xenobiotic stimulus	Mmp7	IMP		Mouse	PMID:11248802

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern