Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Map2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MAP2
- Mouse genes Map2
- Rat genes Map2
- Zfish genes map2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Map2	IMP		Rat	PMID:11029056\|RGD:12793013
Molecular Function	GO:0002162	dystroglycan binding	MAP2	IPI	UniProtKB:Q14118	Human	PMID:18341635
Molecular Function	GO:0008017	microtubule binding	Map2	IDA		Mouse	PMID:17360631
Molecular Function	GO:0008017	microtubule binding	Map2	IMP		Rat	PMID:11029056\|RGD:12793013
Molecular Function	GO:0005515	protein binding	MAP2	IPI	UniProtKB:Q13951	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	Map2	IPI	UniProtKB:Q0KK55	Mouse	MGI:MGI:3769586\|PMID:17984326
Molecular Function	GO:0005515	protein binding	Map2	IPI	UniProtKB:Q0KK55	Mouse	MGI:MGI:5437418\|PMID:21385318
Molecular Function	GO:0005515	protein binding	Map2	IPI	PR:Q99MS8	Mouse	PMID:17360631
Molecular Function	GO:0005515	protein binding	Map2	IPI	RGD:620863	Rat	PMID:15623521\|RGD:1625439
Molecular Function	GO:0005515	protein binding	Map2	IPI	RGD:1343455	Rat	PMID:21632941\|RGD:6483329
Molecular Function	GO:0005515	protein binding	Map2	IPI	UniProtKB:P33176	Rat	PMID:28426968\|RGD:13514087
Molecular Function	GO:0019901	protein kinase binding	Map2	IPI	UniProtKB:P00515,UniProtKB:P31322	Rat	PMID:2561973\|RGD:13514078
Cellular Component	GO:0015629	actin cytoskeleton	Map2	IMP		Rat	PMID:11029056\|RGD:12793013
Cellular Component	GO:0097440	apical dendrite	Map2	IDA		Mouse	PMID:23936366
Cellular Component	GO:0150014	apical distal dendrite	Map2	IDA		Rat	PMID:3517689\|RGD:13514082
Cellular Component	GO:0043203	axon hillock	Map2	IDA		Mouse	MGI:MGI:6148385\|PMID:28426968
Cellular Component	GO:0043203	axon hillock	Map2	IDA		Rat	PMID:28426968\|RGD:13514087
Cellular Component	GO:0043203	axon hillock	Map2	IDA		Rat	PMID:3517689\|RGD:13514082
Cellular Component	GO:0043194	axon initial segment	Map2	IDA		Mouse	MGI:MGI:6148385\|PMID:28426968
Cellular Component	GO:0043194	axon initial segment	Map2	IDA		Rat	PMID:28426968\|RGD:13514087
Cellular Component	GO:0097441	basal dendrite	Map2	IDA		Rat	PMID:3517689\|RGD:13514082
Cellular Component	GO:0097442	CA3 pyramidal cell dendrite	Map2	IDA		Mouse	PMID:18165320
Cellular Component	GO:0044297	cell body	Map2	IDA		Mouse	PMID:17634368
Cellular Component	GO:0044297	cell body	Map2	IDA		Mouse	PMID:15255972
Cellular Component	GO:0005737	cytoplasm	Map2	IDA		Mouse	MGI:MGI:48739
Cellular Component	GO:0005737	cytoplasm	Map2	IDA		Mouse	PMID:15656993
Cellular Component	GO:0005737	cytoplasm	Map2	IMP		Rat	PMID:11029056\|RGD:12793013
Cellular Component	GO:0005737	cytoplasm	Map2	IDA		Rat	PMID:23121659\|RGD:12792285
Cellular Component	GO:0005737	cytoplasm	Map2	IDA		Rat	PMID:2509111\|RGD:13514077
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	MGI:MGI:3769586\|PMID:17984326
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:25918374
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:17634368
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:23861879
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:16980967
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:3147150
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:19208628
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:20600662
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:31787876
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:15255972
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:24554721
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:22523538
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:24035762
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:22022532
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:8535073
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:12074840
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:11834298
Cellular Component	GO:0030425	dendrite	Map2	IDA		Mouse	PMID:15834957
Cellular Component	GO:0030425	dendrite	Map2	IDA		Rat	PMID:10712642\|RGD:8553882
Cellular Component	GO:0030425	dendrite	Map2	IDA		Rat	PMID:15623521\|RGD:1625439
Cellular Component	GO:0030425	dendrite	Map2	IDA		Rat	PMID:17582332\|RGD:8553502
Cellular Component	GO:0030425	dendrite	Map2	IDA		Rat	PMID:28521134\|RGD:13441203
Cellular Component	GO:0032839	dendrite cytoplasm	Map2	IDA		Rat	PMID:3517689\|RGD:13514082
Cellular Component	GO:0044307	dendritic branch	Map2	IDA		Rat	PMID:3835499\|RGD:13514083
Cellular Component	GO:1902737	dendritic filopodium	Map2	IDA		Rat	PMID:3517689\|RGD:13514082
Cellular Component	GO:0044294	dendritic growth cone	Map2	IDA		Rat	PMID:3517689\|RGD:13514082
Cellular Component	GO:0043198	dendritic shaft	Map2	IDA		Mouse	PMID:15996550
Cellular Component	GO:0043198	dendritic shaft	Map2	IDA		Rat	PMID:23121659\|RGD:12792285
Cellular Component	GO:0043198	dendritic shaft	Map2	IDA		Rat	PMID:3835499\|RGD:13514083
Cellular Component	GO:0150002	distal dendrite	Map2	IDA		Rat	PMID:3835499\|RGD:13514083
Cellular Component	GO:0098978	glutamatergic synapse	Map2	IDA		Rat	PMID:2743390\|RGD:155230720
Cellular Component	GO:0005622	intracellular anatomical structure	Map2	IDA		Mouse	PMID:16892058
Cellular Component	GO:0005622	intracellular anatomical structure	Map2	IDA		Mouse	PMID:18268009
Cellular Component	GO:0015630	microtubule cytoskeleton	Map2	IMP		Rat	PMID:11029056\|RGD:12793013
Cellular Component	GO:0043005	neuron projection	Map2	IDA		Mouse	PMID:22523538
Cellular Component	GO:0043005	neuron projection	Map2	IDA		Mouse	PMID:29078390
Cellular Component	GO:0043005	neuron projection	Map2	IDA		Mouse	PMID:18359573
Cellular Component	GO:0043005	neuron projection	Map2	IDA		Rat	PMID:15623521\|RGD:1625439
Cellular Component	GO:0043005	neuron projection	Map2	IDA		Rat	PMID:21119615\|RGD:8554416
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Mouse	MGI:MGI:6148385\|PMID:28426968
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Mouse	PMID:22523538
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Mouse	PMID:18359573
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Mouse	PMID:19646951
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Mouse	PMID:15964665
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Mouse	PMID:12074840
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Rat	PMID:21401443\|RGD:6483087
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Rat	PMID:28426968\|RGD:13514087
Cellular Component	GO:0043025	neuronal cell body	Map2	IDA		Rat	PMID:3835499\|RGD:13514083
Cellular Component	GO:0034399	nuclear periphery	Map2	IDA		Mouse	PMID:11834298
Cellular Component	GO:0098794	postsynapse	Map2	IDA		Rat	PMID:2743390\|RGD:155230720
Cellular Component	GO:0014069	postsynaptic density	Map2	IDA		Mouse	PMID:17114649
Cellular Component	GO:0150001	primary dendrite	Map2	IDA		Rat	PMID:3835499\|RGD:13514083
Cellular Component	GO:0032991	protein-containing complex	Map2	IDA		Rat	PMID:15623521\|RGD:1625439
Cellular Component	GO:1990635	proximal dendrite	Map2	IDA		Rat	PMID:3835499\|RGD:13514083
Cellular Component	GO:1990769	proximal neuron projection	Map2	IDA		Mouse	MGI:MGI:6148385\|PMID:28426968
Cellular Component	GO:1990769	proximal neuron projection	Map2	IDA		Rat	PMID:28426968\|RGD:13514087
Cellular Component	GO:0005791	rough endoplasmic reticulum	Map2	IDA		Rat	PMID:15623521\|RGD:1625439
Cellular Component	GO:0032587	ruffle membrane	Map2	IMP		Rat	PMID:11029056\|RGD:12793013
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Map2	IDA		Rat	PMID:15623521\|RGD:1625439
Biological Process	GO:0007409	axonogenesis	Map2	IMP		Mouse	PMID:11891784
Biological Process	GO:0007409	axonogenesis	Map2	IGI	MGI:MGI:1306778	Mouse	PMID:11891784
Biological Process	GO:0007409	axonogenesis	Map2	IMP		Mouse	PMID:20600662
Biological Process	GO:0071310	cellular response to organic substance	Map2	IDA		Mouse	PMID:18497889
Biological Process	GO:0021954	central nervous system neuron development	MAP2	IEP		Human	PMID:20846339
Biological Process	GO:0016358	dendrite development	Map2	IMP	MGI:MGI:2152587	Mouse	PMID:11581286
Biological Process	GO:0048813	dendrite morphogenesis	MAP2	IEP		Human	PMID:20846339
Biological Process	GO:0030010	establishment of cell polarity	Map2	IMP		Mouse	PMID:20600662
Biological Process	GO:0001578	microtubule bundle formation	Map2	IMP	MGI:MGI:2152587	Mouse	PMID:11581286
Biological Process	GO:0000226	microtubule cytoskeleton organization	Map2	IDA		Mouse	MGI:MGI:6154760\|PMID:10542369
Biological Process	GO:0030517	negative regulation of axon extension	Map2	IMP		Mouse	MGI:MGI:6148385\|PMID:28426968
Biological Process	GO:0030517	negative regulation of axon extension	Map2	IMP		Rat	PMID:28426968\|RGD:13514087
Biological Process	GO:1904527	negative regulation of microtubule binding	Map2	IDA		Rat	PMID:28426968\|RGD:13514087
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	Map2	IMP		Rat	PMID:11029056\|RGD:12793013
Biological Process	GO:0031115	negative regulation of microtubule polymerization	Map2	IMP		Rat	PMID:28426968\|RGD:13514087
Biological Process	GO:0031175	neuron projection development	MAP2	IEP		Human	PMID:20846339
Biological Process	GO:1901953	positive regulation of anterograde dense core granule transport	Map2	IMP		Rat	PMID:28426968\|RGD:13514087
Biological Process	GO:1903744	positive regulation of anterograde synaptic vesicle transport	Map2	IMP		Rat	PMID:28426968\|RGD:13514087
Biological Process	GO:1902513	regulation of organelle transport along microtubule	Map2	IMP		Rat	PMID:28426968\|RGD:13514087
Biological Process	GO:0032880	regulation of protein localization	Map2	IMP		Mouse	MGI:MGI:6148385\|PMID:28426968
Biological Process	GO:0032880	regulation of protein localization	Map2	IMP		Rat	PMID:28426968\|RGD:13514087
Biological Process	GO:0032355	response to estradiol	Map2	IEP		Rat	PMID:21683086\|RGD:6483327
Biological Process	GO:0032570	response to progesterone	Map2	IEP		Rat	PMID:21683086\|RGD:6483327

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.