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Gene Ontology Browser
Term Detail
GO term:microtubule cytoskeleton organization
Synonym: microtubule cytoskeleton organisation
Synonym: microtubule cytoskeleton organization and biogenesis
Synonym: microtubule dynamics
GO id:GO:0000226
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-aorganelle organization
                                        is-acytoskeleton organization
                                                is-aactin cytoskeleton organization +
                                                part-ofcleavage of cytoskeletal proteins involved in execution phase of apoptosis +
                                                is-acortical cytoskeleton organization +
                                                is-acytoskeletal anchoring at nuclear membrane
                                                is-acytoskeletal anchoring at plasma membrane
                                                is-acytoskeletal rearrangement involved in phagocytosis, engulfment
                                                is-aestablishment or maintenance of cytoskeleton polarity +
                                                is-aintermediate filament cytoskeleton organization +
                                                is-amicrotubule cytoskeleton organization [GO:0000226] (282 genes, 447 annotations)
                                                        is-acytoplasmic microtubule organization +
                                                        is-aequatorial microtubule organization +
                                                        is-aestablishment of spindle localization +
                                                        is-aestablishment or maintenance of microtubule cytoskeleton polarity +
                                                        is-ahorsetail-astral microtubule organization
                                                        is-amicrotubule anchoring +
                                                        is-amicrotubule bundle formation +
                                                        is-amicrotubule cytoskeleton organization involved in establishment of planar polarity +
                                                        is-amicrotubule cytoskeleton organization involved in synapsis
                                                        is-amicrotubule nucleation +
                                                        part-ofmicrotubule organizing center organization +
                                                        is-amicrotubule polymerization or depolymerization +
                                                        is-amodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration +
                                                        is-aphragmoplast microtubule organization +
                                                        is-aradial microtubular system formation
                                                        regulatesregulation of microtubule cytoskeleton organization +
                                                        is-asperm aster formation
                                                        is-aspindle organization +
                                                negatively-regulatesnegative regulation of cytoskeleton organization +
                                                positively-regulatespositive regulation of cytoskeleton organization +
                                                is-apostsynaptic density organization +
                                                regulatesregulation of cytoskeleton organization +
                                                is-aseptin cytoskeleton organization +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-amicrotubule-based process
                                        is-aattachment of telomeric heterochromatin to spindle pole body
                                        is-acentriole replication +
                                        is-aestablishment of mitochondrion localization, microtubule-mediated +
                                        is-aM phase specific microtubule process
                                        is-amicrotubule cytoskeleton organization [GO:0000226] (282 genes, 447 annotations)
                                                is-acytoplasmic microtubule organization +
                                                is-aequatorial microtubule organization +
                                                is-aestablishment of spindle localization +
                                                is-aestablishment or maintenance of microtubule cytoskeleton polarity +
                                                is-ahorsetail-astral microtubule organization
                                                is-amicrotubule anchoring +
                                                is-amicrotubule bundle formation +
                                                is-amicrotubule cytoskeleton organization involved in establishment of planar polarity +
                                                is-amicrotubule cytoskeleton organization involved in synapsis
                                                is-amicrotubule nucleation +
                                                part-ofmicrotubule organizing center organization +
                                                is-amicrotubule polymerization or depolymerization +
                                                is-amodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration +
                                                is-aphragmoplast microtubule organization +
                                                is-aradial microtubular system formation
                                                regulatesregulation of microtubule cytoskeleton organization +
                                                is-asperm aster formation
                                                is-aspindle organization +
                                        is-amicrotubule severing
                                        is-amicrotubule-based movement +
                                        is-amicrotubule-based peroxisome localization
                                        is-aoocyte microtubule cytoskeleton polarization
                                        regulatesregulation of microtubule-based process +
                                        is-aspindle elongation +
                                        is-aspindle midzone assembly +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-aorganelle organization
                                        is-acytoskeleton organization
                                                is-aactin cytoskeleton organization +
                                                part-ofcleavage of cytoskeletal proteins involved in execution phase of apoptosis +
                                                is-acortical cytoskeleton organization +
                                                is-acytoskeletal anchoring at nuclear membrane
                                                is-acytoskeletal anchoring at plasma membrane
                                                is-acytoskeletal rearrangement involved in phagocytosis, engulfment
                                                is-aestablishment or maintenance of cytoskeleton polarity +
                                                is-aintermediate filament cytoskeleton organization +
                                                is-amicrotubule cytoskeleton organization [GO:0000226] (282 genes, 447 annotations)
                                                        is-acytoplasmic microtubule organization +
                                                        is-aequatorial microtubule organization +
                                                        is-aestablishment of spindle localization +
                                                        is-aestablishment or maintenance of microtubule cytoskeleton polarity +
                                                        is-ahorsetail-astral microtubule organization
                                                        is-amicrotubule anchoring +
                                                        is-amicrotubule bundle formation +
                                                        is-amicrotubule cytoskeleton organization involved in establishment of planar polarity +
                                                        is-amicrotubule cytoskeleton organization involved in synapsis
                                                        is-amicrotubule nucleation +
                                                        part-ofmicrotubule organizing center organization +
                                                        is-amicrotubule polymerization or depolymerization +
                                                        is-amodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration +
                                                        is-aphragmoplast microtubule organization +
                                                        is-aradial microtubular system formation
                                                        regulatesregulation of microtubule cytoskeleton organization +
                                                        is-asperm aster formation
                                                        is-aspindle organization +
                                                negatively-regulatesnegative regulation of cytoskeleton organization +
                                                positively-regulatespositive regulation of cytoskeleton organization +
                                                is-apostsynaptic density organization +
                                                regulatesregulation of cytoskeleton organization +
                                                is-aseptin cytoskeleton organization +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-amicrotubule-based process
                                        is-aattachment of telomeric heterochromatin to spindle pole body
                                        is-acentriole replication +
                                        is-aestablishment of mitochondrion localization, microtubule-mediated +
                                        is-aM phase specific microtubule process
                                        is-amicrotubule cytoskeleton organization [GO:0000226] (282 genes, 447 annotations)
                                                is-acytoplasmic microtubule organization +
                                                is-aequatorial microtubule organization +
                                                is-aestablishment of spindle localization +
                                                is-aestablishment or maintenance of microtubule cytoskeleton polarity +
                                                is-ahorsetail-astral microtubule organization
                                                is-amicrotubule anchoring +
                                                is-amicrotubule bundle formation +
                                                is-amicrotubule cytoskeleton organization involved in establishment of planar polarity +
                                                is-amicrotubule cytoskeleton organization involved in synapsis
                                                is-amicrotubule nucleation +
                                                part-ofmicrotubule organizing center organization +
                                                is-amicrotubule polymerization or depolymerization +
                                                is-amodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration +
                                                is-aphragmoplast microtubule organization +
                                                is-aradial microtubular system formation
                                                regulatesregulation of microtubule cytoskeleton organization +
                                                is-asperm aster formation
                                                is-aspindle organization +
                                        is-amicrotubule severing
                                        is-amicrotubule-based movement +
                                        is-amicrotubule-based peroxisome localization
                                        is-aoocyte microtubule cytoskeleton polarization
                                        regulatesregulation of microtubule-based process +
                                        is-aspindle elongation +
                                        is-aspindle midzone assembly +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-aorganelle organization
                                        is-acytoskeleton organization
                                                is-aactin cytoskeleton organization +
                                                part-ofcleavage of cytoskeletal proteins involved in execution phase of apoptosis +
                                                is-acortical cytoskeleton organization +
                                                is-acytoskeletal anchoring at nuclear membrane
                                                is-acytoskeletal anchoring at plasma membrane
                                                is-acytoskeletal rearrangement involved in phagocytosis, engulfment
                                                is-aestablishment or maintenance of cytoskeleton polarity +
                                                is-aintermediate filament cytoskeleton organization +
                                                is-amicrotubule cytoskeleton organization [GO:0000226] (282 genes, 447 annotations)
                                                        is-acytoplasmic microtubule organization +
                                                        is-aequatorial microtubule organization +
                                                        is-aestablishment of spindle localization +
                                                        is-aestablishment or maintenance of microtubule cytoskeleton polarity +
                                                        is-ahorsetail-astral microtubule organization
                                                        is-amicrotubule anchoring +
                                                        is-amicrotubule bundle formation +
                                                        is-amicrotubule cytoskeleton organization involved in establishment of planar polarity +
                                                        is-amicrotubule cytoskeleton organization involved in synapsis
                                                        is-amicrotubule nucleation +
                                                        part-ofmicrotubule organizing center organization +
                                                        is-amicrotubule polymerization or depolymerization +
                                                        is-amodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration +
                                                        is-aphragmoplast microtubule organization +
                                                        is-aradial microtubular system formation
                                                        regulatesregulation of microtubule cytoskeleton organization +
                                                        is-asperm aster formation
                                                        is-aspindle organization +
                                                negatively-regulatesnegative regulation of cytoskeleton organization +
                                                positively-regulatespositive regulation of cytoskeleton organization +
                                                is-apostsynaptic density organization +
                                                regulatesregulation of cytoskeleton organization +
                                                is-aseptin cytoskeleton organization +


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last database update
06/05/2013
MGI 5.13
The Jackson Laboratory