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Gene Ontology Browser
Term Detail
GO term:axon initial segment
Synonym: initial segment
GO id:GO:0043194
Definition:Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
Number of paths to term: 20

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection
                                        part-ofcell projection part
                                                is-aaxon part
                                                        is-aaxolemma
                                                        is-aaxon collateral +
                                                        is-aaxon hillock
                                                        is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                        is-aaxon microtubule bundle
                                                        is-aaxon terminus +
                                                        is-aaxonal growth cone
                                                        is-aaxonal spine
                                                        is-ainternode region of axon
                                                        is-ajuxtaparanode region of axon
                                                        is-amain axon +
                                                        is-anode of Ranvier
                                                        is-aparallel fiber
                                                        is-aparanode region of axon
                                                        is-apericellular basket
                                                        is-apinceau fiber
                                                        is-asubsynaptic reticulum
                                                        is-asynaptic vesicle, readily releasable pool
                                                        is-asynaptic vesicle, recycling pool
                                                        is-asynaptic vesicle, resting pool
                                                        is-aterminal bouton +
                                                        is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection
                                        part-ofcell projection part
                                                is-aaxon part
                                                        is-amain axon
                                                                part-ofaxolemma
                                                                part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                                part-ofinternode region of axon
                                                                part-ofjuxtaparanode region of axon
                                                                part-ofnode of Ranvier
                                                                part-ofparanode region of axon
                                                                part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection
                                        is-aneuron projection
                                                is-aaxon
                                                        part-ofaxon part
                                                                is-aaxolemma
                                                                is-aaxon collateral +
                                                                is-aaxon hillock
                                                                is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                                is-aaxon microtubule bundle
                                                                is-aaxon terminus +
                                                                is-aaxonal growth cone
                                                                is-aaxonal spine
                                                                is-ainternode region of axon
                                                                is-ajuxtaparanode region of axon
                                                                is-amain axon +
                                                                is-anode of Ranvier
                                                                is-aparallel fiber
                                                                is-aparanode region of axon
                                                                is-apericellular basket
                                                                is-apinceau fiber
                                                                is-asubsynaptic reticulum
                                                                is-asynaptic vesicle, readily releasable pool
                                                                is-asynaptic vesicle, recycling pool
                                                                is-asynaptic vesicle, resting pool
                                                                is-aterminal bouton +
                                                                is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection
                                        is-aneuron projection
                                                is-aaxon
                                                        part-ofaxon part
                                                                is-amain axon
                                                                        part-ofaxolemma
                                                                        part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                                        part-ofinternode region of axon
                                                                        part-ofjuxtaparanode region of axon
                                                                        part-ofnode of Ranvier
                                                                        part-ofparanode region of axon
                                                                        part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection part
                                        is-aaxon part
                                                is-aaxolemma
                                                is-aaxon collateral +
                                                is-aaxon hillock
                                                is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                is-aaxon microtubule bundle
                                                is-aaxon terminus +
                                                is-aaxonal growth cone
                                                is-aaxonal spine
                                                is-ainternode region of axon
                                                is-ajuxtaparanode region of axon
                                                is-amain axon +
                                                is-anode of Ranvier
                                                is-aparallel fiber
                                                is-aparanode region of axon
                                                is-apericellular basket
                                                is-apinceau fiber
                                                is-asubsynaptic reticulum
                                                is-asynaptic vesicle, readily releasable pool
                                                is-asynaptic vesicle, recycling pool
                                                is-asynaptic vesicle, resting pool
                                                is-aterminal bouton +
                                                is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell projection part
                                        is-aaxon part
                                                is-amain axon
                                                        part-ofaxolemma
                                                        part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                        part-ofinternode region of axon
                                                        part-ofjuxtaparanode region of axon
                                                        part-ofnode of Ranvier
                                                        part-ofparanode region of axon
                                                        part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aneuron part
                                        is-aaxon part
                                                is-aaxolemma
                                                is-aaxon collateral +
                                                is-aaxon hillock
                                                is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                is-aaxon microtubule bundle
                                                is-aaxon terminus +
                                                is-aaxonal growth cone
                                                is-aaxonal spine
                                                is-ainternode region of axon
                                                is-ajuxtaparanode region of axon
                                                is-amain axon +
                                                is-anode of Ranvier
                                                is-aparallel fiber
                                                is-aparanode region of axon
                                                is-apericellular basket
                                                is-apinceau fiber
                                                is-asubsynaptic reticulum
                                                is-asynaptic vesicle, readily releasable pool
                                                is-asynaptic vesicle, recycling pool
                                                is-asynaptic vesicle, resting pool
                                                is-aterminal bouton +
                                                is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aneuron part
                                        is-aaxon part
                                                is-amain axon
                                                        part-ofaxolemma
                                                        part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                        part-ofinternode region of axon
                                                        part-ofjuxtaparanode region of axon
                                                        part-ofnode of Ranvier
                                                        part-ofparanode region of axon
                                                        part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aneuron part
                                        is-aneuron projection
                                                is-aaxon
                                                        part-ofaxon part
                                                                is-aaxolemma
                                                                is-aaxon collateral +
                                                                is-aaxon hillock
                                                                is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                                is-aaxon microtubule bundle
                                                                is-aaxon terminus +
                                                                is-aaxonal growth cone
                                                                is-aaxonal spine
                                                                is-ainternode region of axon
                                                                is-ajuxtaparanode region of axon
                                                                is-amain axon +
                                                                is-anode of Ranvier
                                                                is-aparallel fiber
                                                                is-aparanode region of axon
                                                                is-apericellular basket
                                                                is-apinceau fiber
                                                                is-asubsynaptic reticulum
                                                                is-asynaptic vesicle, readily releasable pool
                                                                is-asynaptic vesicle, recycling pool
                                                                is-asynaptic vesicle, resting pool
                                                                is-aterminal bouton +
                                                                is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aneuron part
                                        is-aneuron projection
                                                is-aaxon
                                                        part-ofaxon part
                                                                is-amain axon
                                                                        part-ofaxolemma
                                                                        part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                                        part-ofinternode region of axon
                                                                        part-ofjuxtaparanode region of axon
                                                                        part-ofnode of Ranvier
                                                                        part-ofparanode region of axon
                                                                        part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection
                                part-ofcell projection part
                                        is-aaxon part
                                                is-aaxolemma
                                                is-aaxon collateral +
                                                is-aaxon hillock
                                                is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                is-aaxon microtubule bundle
                                                is-aaxon terminus +
                                                is-aaxonal growth cone
                                                is-aaxonal spine
                                                is-ainternode region of axon
                                                is-ajuxtaparanode region of axon
                                                is-amain axon +
                                                is-anode of Ranvier
                                                is-aparallel fiber
                                                is-aparanode region of axon
                                                is-apericellular basket
                                                is-apinceau fiber
                                                is-asubsynaptic reticulum
                                                is-asynaptic vesicle, readily releasable pool
                                                is-asynaptic vesicle, recycling pool
                                                is-asynaptic vesicle, resting pool
                                                is-aterminal bouton +
                                                is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection
                                part-ofcell projection part
                                        is-aaxon part
                                                is-amain axon
                                                        part-ofaxolemma
                                                        part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                        part-ofinternode region of axon
                                                        part-ofjuxtaparanode region of axon
                                                        part-ofnode of Ranvier
                                                        part-ofparanode region of axon
                                                        part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection
                                is-aneuron projection
                                        is-aaxon
                                                part-ofaxon part
                                                        is-aaxolemma
                                                        is-aaxon collateral +
                                                        is-aaxon hillock
                                                        is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                        is-aaxon microtubule bundle
                                                        is-aaxon terminus +
                                                        is-aaxonal growth cone
                                                        is-aaxonal spine
                                                        is-ainternode region of axon
                                                        is-ajuxtaparanode region of axon
                                                        is-amain axon +
                                                        is-anode of Ranvier
                                                        is-aparallel fiber
                                                        is-aparanode region of axon
                                                        is-apericellular basket
                                                        is-apinceau fiber
                                                        is-asubsynaptic reticulum
                                                        is-asynaptic vesicle, readily releasable pool
                                                        is-asynaptic vesicle, recycling pool
                                                        is-asynaptic vesicle, resting pool
                                                        is-aterminal bouton +
                                                        is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection
                                is-aneuron projection
                                        is-aaxon
                                                part-ofaxon part
                                                        is-amain axon
                                                                part-ofaxolemma
                                                                part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                                part-ofinternode region of axon
                                                                part-ofjuxtaparanode region of axon
                                                                part-ofnode of Ranvier
                                                                part-ofparanode region of axon
                                                                part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection part
                                is-aaxon part
                                        is-aaxolemma
                                        is-aaxon collateral +
                                        is-aaxon hillock
                                        is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                        is-aaxon microtubule bundle
                                        is-aaxon terminus +
                                        is-aaxonal growth cone
                                        is-aaxonal spine
                                        is-ainternode region of axon
                                        is-ajuxtaparanode region of axon
                                        is-amain axon +
                                        is-anode of Ranvier
                                        is-aparallel fiber
                                        is-aparanode region of axon
                                        is-apericellular basket
                                        is-apinceau fiber
                                        is-asubsynaptic reticulum
                                        is-asynaptic vesicle, readily releasable pool
                                        is-asynaptic vesicle, recycling pool
                                        is-asynaptic vesicle, resting pool
                                        is-aterminal bouton +
                                        is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell projection part
                                is-aaxon part
                                        is-amain axon
                                                part-ofaxolemma
                                                part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                part-ofinternode region of axon
                                                part-ofjuxtaparanode region of axon
                                                part-ofnode of Ranvier
                                                part-ofparanode region of axon
                                                part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aneuron part
                                is-aaxon part
                                        is-aaxolemma
                                        is-aaxon collateral +
                                        is-aaxon hillock
                                        is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                        is-aaxon microtubule bundle
                                        is-aaxon terminus +
                                        is-aaxonal growth cone
                                        is-aaxonal spine
                                        is-ainternode region of axon
                                        is-ajuxtaparanode region of axon
                                        is-amain axon +
                                        is-anode of Ranvier
                                        is-aparallel fiber
                                        is-aparanode region of axon
                                        is-apericellular basket
                                        is-apinceau fiber
                                        is-asubsynaptic reticulum
                                        is-asynaptic vesicle, readily releasable pool
                                        is-asynaptic vesicle, recycling pool
                                        is-asynaptic vesicle, resting pool
                                        is-aterminal bouton +
                                        is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aneuron part
                                is-aaxon part
                                        is-amain axon
                                                part-ofaxolemma
                                                part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                part-ofinternode region of axon
                                                part-ofjuxtaparanode region of axon
                                                part-ofnode of Ranvier
                                                part-ofparanode region of axon
                                                part-ofvaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aneuron part
                                is-aneuron projection
                                        is-aaxon
                                                part-ofaxon part
                                                        is-aaxolemma
                                                        is-aaxon collateral +
                                                        is-aaxon hillock
                                                        is-aaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                        is-aaxon microtubule bundle
                                                        is-aaxon terminus +
                                                        is-aaxonal growth cone
                                                        is-aaxonal spine
                                                        is-ainternode region of axon
                                                        is-ajuxtaparanode region of axon
                                                        is-amain axon +
                                                        is-anode of Ranvier
                                                        is-aparallel fiber
                                                        is-aparanode region of axon
                                                        is-apericellular basket
                                                        is-apinceau fiber
                                                        is-asubsynaptic reticulum
                                                        is-asynaptic vesicle, readily releasable pool
                                                        is-asynaptic vesicle, recycling pool
                                                        is-asynaptic vesicle, resting pool
                                                        is-aterminal bouton +
                                                        is-avaricosity


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aneuron part
                                is-aneuron projection
                                        is-aaxon
                                                part-ofaxon part
                                                        is-amain axon
                                                                part-ofaxolemma
                                                                part-ofaxon initial segment [GO:0043194] (13 genes, 15 annotations)
                                                                part-ofinternode region of axon
                                                                part-ofjuxtaparanode region of axon
                                                                part-ofnode of Ranvier
                                                                part-ofparanode region of axon
                                                                part-ofvaricosity


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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory