Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Magi2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MAGI2
- Mouse genes Magi2
- Rat genes Magi2
- Zfish genes magi2a,magi2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Magi2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070697	activin receptor binding	Magi2	IPI	PR:P27038	Mouse	PMID:10681527
Molecular Function	GO:0031697	beta-1 adrenergic receptor binding	MAGI2	IPI	UniProtKB:P08588	Human	PMID:11526121
Molecular Function	GO:0019894	kinesin binding	Magi2	IPI	RGD:621520	Rat	PMID:12097473\|RGD:8553481
Molecular Function	GO:0019902	phosphatase binding	MAGI2	IPI	UniProtKB:P60484	Human	PMID:10760291
Molecular Function	GO:0005515	protein binding	MAGI2	IPI	UniProtKB:Q9Y4G8	Human	PMID:10548487
Molecular Function	GO:0005515	protein binding	MAGI2	IPI	UniProtKB:P08588	Human	PMID:16316992
Molecular Function	GO:0005515	protein binding	MAGI2	IPI	UniProtKB:P08588	Human	PMID:16533813
Molecular Function	GO:0005515	protein binding	MAGI2	IPI	UniProtKB:P54259	Human	PMID:9647693
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q3TES0	Mouse	MGI:MGI:4946863\|PMID:21198641
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q495M9	Mouse	MGI:MGI:5573004\|PMID:24608321
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q61483	Mouse	MGI:MGI:3688362\|PMID:14529612
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:O00548	Mouse	MGI:MGI:5693234\|PMID:15509766
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q61483	Mouse	MGI:MGI:5921638\|PMID:24025447
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:F1M386	Rat	PMID:10548487\|RGD:8554081
Molecular Function	GO:0005515	protein binding	Magi2	IPI	RGD:68424	Rat	PMID:10644767\|RGD:632272
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q8R4T5	Rat	PMID:12586822\|RGD:1299234
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q63226	Rat	PMID:12589829\|RGD:632941
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:P60484	Rat	PMID:15951562\|RGD:8554534
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q9R044	Rat	PMID:15994232\|RGD:8553727
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:O94850	Rat	PMID:16751601\|RGD:8554160
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q8R4T5	Rat	PMID:17396155\|RGD:8553557
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:F1M386	Rat	PMID:17724123\|RGD:8554481
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q9EQG6-2	Rat	PMID:17724123\|RGD:8554481
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q91ZD4	Rat	PMID:20534871\|RGD:8553386
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:Q9R044	Rat	PMID:20534871\|RGD:8553386
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:P34998	Rat	PMID:26352593\|RGD:13702239
Molecular Function	GO:0005515	protein binding	Magi2	IPI	UniProtKB:P97836	Rat	PMID:9694864\|RGD:632273
Molecular Function	GO:0044877	protein-containing complex binding	Magi2	IDA		Rat	PMID:10644767\|RGD:632272
Molecular Function	GO:0044877	protein-containing complex binding	Magi2	IPI	RGD:620460	Rat	PMID:15331416\|RGD:1600864
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	MAGI2	IDA		Human	PMID:11526121
Molecular Function	GO:0046332	SMAD binding	Magi2	IPI	UniProtKB:P84022	Mouse	MGI:MGI:1353670\|PMID:10681527
Molecular Function	GO:0098919	structural constituent of postsynaptic density	Magi2	IDA		Rat	PMID:22593065\|RGD:13702450
Molecular Function	GO:0098919	structural constituent of postsynaptic density	Magi2	IMP		Rat	PMID:22593065\|RGD:13702450
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	Magi2	IDA		Rat	PMID:23751499\|RGD:13702234
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	Magi2	IMP		Rat	PMID:23751499\|RGD:13702234
Molecular Function	GO:0070699	type II activin receptor binding	Magi2	IPI	UniProtKB:P27038	Mouse	MGI:MGI:3623710\|PMID:16648306
Cellular Component	GO:0005923	bicellular tight junction	MAGI2	IDA		Human	PMID:10760291
Cellular Component	GO:0005814	centriole	Magi2	IDA		Mouse	MGI:MGI:5573004\|PMID:24608321
Cellular Component	GO:0097546	ciliary base	Magi2	IDA		Mouse	MGI:MGI:5573004\|PMID:24608321
Cellular Component	GO:0005737	cytoplasm	MAGI2	IDA		Human	PMID:11526121
Cellular Component	GO:0005737	cytoplasm	Magi2	IDA		Mouse	MGI:MGI:3652669\|PMID:16870733
Cellular Component	GO:0005737	cytoplasm	Magi2	IDA		Rat	PMID:17724123\|RGD:8554481
Cellular Component	GO:0030425	dendrite	Magi2	IDA		Mouse	MGI:MGI:4457945\|PMID:20534458
Cellular Component	GO:0030425	dendrite	Magi2	IDA		Rat	PMID:10548487\|RGD:8554081
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	Magi2	IDA		Rat	PMID:17059560\|RGD:13702466
Cellular Component	GO:0098982	GABA-ergic synapse	Magi2	IDA		Rat	PMID:17059560\|RGD:13702466
Cellular Component	GO:0098982	GABA-ergic synapse	Magi2	IDA		Rat	PMID:23751499\|RGD:13702234
Cellular Component	GO:0098982	GABA-ergic synapse	Magi2	IMP		Rat	PMID:23751499\|RGD:13702234
Cellular Component	GO:0098978	glutamatergic synapse	Magi2	IDA		Rat	PMID:22593065\|RGD:13702450
Cellular Component	GO:0098978	glutamatergic synapse	Magi2	IMP		Rat	PMID:22593065\|RGD:13702450
Cellular Component	GO:0098978	glutamatergic synapse	Magi2	IDA		Rat	PMID:9694864\|RGD:632273
Cellular Component	GO:0005770	late endosome	Magi2	IDA		Rat	PMID:17724123\|RGD:8554481
Cellular Component	GO:0005634	nucleus	MAGI2	IDA		Human	PMID:10760291
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Magi2	IDA		Rat	PMID:12589829\|RGD:632941
Cellular Component	GO:0001917	photoreceptor inner segment	Magi2	IDA		Mouse	MGI:MGI:5573004\|PMID:24608321
Cellular Component	GO:0001750	photoreceptor outer segment	Magi2	IDA		Mouse	MGI:MGI:5573004\|PMID:24608321
Cellular Component	GO:0005886	plasma membrane	MAGI2	IDA		Human	PMID:10760291
Cellular Component	GO:0005886	plasma membrane	MAGI2	IDA		Human	PMID:11526121
Cellular Component	GO:0005886	plasma membrane	Magi2	IDA		Mouse	MGI:MGI:3652669\|PMID:16870733
Cellular Component	GO:0014069	postsynaptic density	Magi2	IDA		Rat	PMID:9694864\|RGD:632273
Cellular Component	GO:0014069	postsynaptic density	Magi2	IDA		Rat	PMID:12589829\|RGD:632941
Cellular Component	GO:0032991	protein-containing complex	Magi2	IDA		Rat	PMID:15331416\|RGD:1600864
Cellular Component	GO:0032991	protein-containing complex	Magi2	IDA		Rat	PMID:17724123\|RGD:8554481
Cellular Component	GO:0036057	slit diaphragm	Magi2	IDA		Rat	PMID:15994232\|RGD:8553727
Cellular Component	GO:0045202	synapse	Magi2	IDA		Rat	PMID:10548487\|RGD:8554081
Cellular Component	GO:0045202	synapse	Magi2	IDA		Rat	PMID:10681527\|RGD:8554655
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Magi2	IDA		Rat	PMID:17724123\|RGD:8554481
Biological Process	GO:0072583	clathrin-dependent endocytosis	Magi2	IMP		Mouse	MGI:MGI:5573004\|PMID:24608321
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	Magi2	IDA		Mouse	MGI:MGI:1353670\|PMID:10681527
Biological Process	GO:0030336	negative regulation of cell migration	Magi2	IDA		Rat	PMID:17880912\|RGD:8553803
Biological Process	GO:0008285	negative regulation of cell population proliferation	Magi2	IDA		Rat	PMID:17880912\|RGD:8553803
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	MAGI2	IDA		Human	PMID:10760291
Biological Process	GO:0038180	nerve growth factor signaling pathway	Magi2	IDA		Rat	PMID:17724123\|RGD:8554481
Biological Process	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly	Magi2	IDA		Mouse	MGI:MGI:4457945\|PMID:20534458
Biological Process	GO:0072015	podocyte development	Magi2	IEP		Rat	PMID:15994232\|RGD:8553727
Biological Process	GO:0010976	positive regulation of neuron projection development	Magi2	IMP		Rat	PMID:17724123\|RGD:8554481
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	MAGI2	IDA		Human	PMID:10760291
Biological Process	GO:0002092	positive regulation of receptor internalization	MAGI2	IDA		Human	PMID:11526121
Biological Process	GO:2000809	positive regulation of synaptic vesicle clustering	Magi2	IDA		Mouse	MGI:MGI:4457945\|PMID:20534458
Biological Process	GO:0039021	pronephric glomerulus development	magi2a	IMP	ZFIN:ZDB-MRPHLNO-160106-3	Zfish	PMID:25556170
Biological Process	GO:0043113	receptor clustering	Magi2	IDA		Rat	PMID:10644767\|RGD:632272
Biological Process	GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Magi2	IDA		Rat	PMID:22593065\|RGD:13702450
Biological Process	GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Magi2	IMP		Rat	PMID:22593065\|RGD:13702450
Biological Process	GO:0099179	regulation of synaptic membrane adhesion	Magi2	IDA		Rat	PMID:23751499\|RGD:13702234
Biological Process	GO:0099179	regulation of synaptic membrane adhesion	Magi2	IMP		Rat	PMID:23751499\|RGD:13702234
Biological Process	GO:0007165	signal transduction	Magi2	IPI	PR:P27038	Mouse	PMID:10681527
Biological Process	GO:0060395	SMAD protein signal transduction	Magi2	IDA		Mouse	MGI:MGI:1353670\|PMID:10681527

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.