| GO term: | tight junction |
| Synonym: | zonula occludens |
| GO id: | GO:0005923 |
| Definition: | An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcell junctioncell-cell junctionapical junction complexseptate junction +subapical complextight junction [GO:0005923] (104 genes, 120 annotations)host-symbiont tight junctionzonula adherens +cellular_componentcell junctioncell-cell junctionoccluding junctionseptate junction +tight junction [GO:0005923] (104 genes, 120 annotations)host-symbiont tight junctionMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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