Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRC7
  • Mouse genes Lrrc7
  • Rat genes Lrrc7
  • Zfish genes lrrc7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrc7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LRRC7	IPI	UniProtKB:Q9Z1T4	Human	PMID:12390249
Molecular Function	GO:0005515	protein binding	LRRC7	IPI	UniProtKB:Q9UQM7	Human	PMID:28130356
Molecular Function	GO:0005515	protein binding	Lrrc7	IPI	UniProtKB:P31016	Rat	PMID:12390249|RGD:8553985
Molecular Function	GO:0005515	protein binding	Lrrc7	IPI	UniProtKB:Q9Z1T4	Rat	PMID:12390249|RGD:8553985
Molecular Function	GO:0005515	protein binding	Lrrc7	IPI	UniProtKB:P11275	Rat	PMID:16120608|RGD:2314407
Molecular Function	GO:0005515	protein binding	Lrrc7	IPI	UniProtKB:P11798	Rat	PMID:16120608|RGD:2314407
Molecular Function	GO:0019901	protein kinase binding	Lrrc7	IPI	RGD:2261	Rat	PMID:16120608|RGD:2314407
Cellular Component	GO:0015629	actin cytoskeleton	Lrrc7	IDA		Rat	PMID:18248607|RGD:2314403
Cellular Component	GO:0043194	axon initial segment	Lrrc7	IDA		Rat	PMID:8824323|RGD:1299511
Cellular Component	GO:0005737	cytoplasm	Lrrc7	IDA		Rat	PMID:18248607|RGD:2314403
Cellular Component	GO:0043197	dendritic spine	Lrrc7	IDA		Rat	PMID:8824323|RGD:1299511
Cellular Component	GO:0030175	filopodium	Lrrc7	IDA		Rat	PMID:18248607|RGD:2314403
Cellular Component	GO:0098978	glutamatergic synapse	Lrrc7	IDA		Rat	PMID:8824323|RGD:1299511
Cellular Component	GO:0043005	neuron projection	Lrrc7	IDA		Rat	PMID:15647492|RGD:2314408
Cellular Component	GO:0043005	neuron projection	Lrrc7	IDA		Rat	PMID:8824323|RGD:1299511
Cellular Component	GO:0005886	plasma membrane	Lrrc7	IDA		Rat	PMID:18248607|RGD:2314403
Cellular Component	GO:0014069	postsynaptic density	Lrrc7	IDA		Rat	PMID:8824323|RGD:1299511
Cellular Component	GO:0098839	postsynaptic density membrane	Lrrc7	IDA		Rat	PMID:8824323|RGD:1299511
Cellular Component	GO:0045202	synapse	Lrrc7	IDA		Rat	PMID:8824323|RGD:1299511
Biological Process	GO:0010976	positive regulation of neuron projection development	Lrrc7	IDA		Rat	PMID:15647492|RGD:2314408
Biological Process	GO:0014070	response to organic cyclic compound	Lrrc7	IEP		Rat	PMID:19038319|RGD:2314402

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern