Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Grin3a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GRIN3A
- Mouse genes Grin3a
- Rat genes Grin3a
- Zfish genes grin3a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grin3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005262	calcium channel activity	Grin3a	IDA		Mouse	PMID:9620802
Molecular Function	GO:0005262	calcium channel activity	Grin3a	IMP	MGI:MGI:2387963	Mouse	PMID:14507892
Molecular Function	GO:0016594	glycine binding	GRIN3A	IDA		Human	PMID:17320117
Molecular Function	GO:0016594	glycine binding	Grin3a	IDA		Rat	PMID:17182766\|RGD:8553928
Molecular Function	GO:0042802	identical protein binding	GRIN3A	IPI	UniProtKB:Q8TCU5	Human	PMID:17997397
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	Grin3a	IDA		Rat	PMID:16477151\|RGD:1642190
Molecular Function	GO:0042165	neurotransmitter binding	Grin3a	IDA		Rat	PMID:16477151\|RGD:1642190
Molecular Function	GO:0004972	NMDA glutamate receptor activity	GRIN3A	IDA		Human	PMID:17502428
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin3a	IMP	MGI:MGI:2387963	Mouse	PMID:14507892
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin3a	IPI	PR:P35438	Mouse	PMID:9620802
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin3a	IDA		Rat	PMID:17182766\|RGD:8553928
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin3a	IDA		Rat	PMID:16477151\|RGD:1642190
Molecular Function	GO:0005515	protein binding	GRIN3A	IPI	UniProtKB:Q66K74	Human	PMID:17658481
Molecular Function	GO:0005515	protein binding	GRIN3A	IPI	UniProtKB:Q05586	Human	PMID:17997397
Molecular Function	GO:0005515	protein binding	GRIN3A	IPI	UniProtKB:Q12879	Human	PMID:17997397
Molecular Function	GO:0005515	protein binding	GRIN3A	IPI	UniProtKB:Q13224	Human	PMID:17997397
Molecular Function	GO:0005515	protein binding	Grin3a	IPI	UniProtKB:Q68FF6	Mouse	MGI:MGI:5545681\|PMID:24297929
Molecular Function	GO:0005515	protein binding	Grin3a	IPI	PR:P35438	Mouse	PMID:9620802
Molecular Function	GO:0005515	protein binding	Grin3a	IPI	UniProtKB:P0C5W1	Rat	PMID:17658481\|RGD:8553944
Molecular Function	GO:0005515	protein binding	Grin3a	IPI	UniProtKB:Q9Z272	Rat	PMID:24297929\|RGD:42721994
Molecular Function	GO:0051721	protein phosphatase 2A binding	Grin3a	IDA		Rat	PMID:15194871\|RGD:1642193
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Grin3a	IDA		Mouse	PMID:24183704
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Grin3a	IMP		Mouse	PMID:24183704
Cellular Component	GO:0098978	glutamatergic synapse	Grin3a	IMP		Mouse	PMID:25144876
Cellular Component	GO:0098978	glutamatergic synapse	Grin3a	IDA		Mouse	PMID:25144876
Cellular Component	GO:0098978	glutamatergic synapse	Grin3a	IDA		Mouse	PMID:24183704
Cellular Component	GO:0098978	glutamatergic synapse	Grin3a	IMP		Mouse	PMID:24183704
Cellular Component	GO:0098978	glutamatergic synapse	Grin3a	IDA		Rat	PMID:16617342\|RGD:13702454
Cellular Component	GO:0016020	membrane	GRIN3A	IDA		Human	PMID:17997397
Cellular Component	GO:0043005	neuron projection	GRIN3A	IDA		Human	PMID:17658481
Cellular Component	GO:0043025	neuronal cell body	GRIN3A	IDA		Human	PMID:17658481
Cellular Component	GO:0043025	neuronal cell body	Grin3a	IDA		Mouse	PMID:14507892
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	GRIN3A	IDA		Human	PMID:17997397
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin3a	IDA		Rat	PMID:16477151\|RGD:1642190
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin3a	IDA		Rat	PMID:17182766\|RGD:8553928
Cellular Component	GO:0098839	postsynaptic density membrane	Grin3a	IDA		Rat	PMID:16617342\|RGD:13702454
Cellular Component	GO:0045211	postsynaptic membrane	Grin3a	IDA		Mouse	PMID:9620802
Cellular Component	GO:0045211	postsynaptic membrane	Grin3a	IDA		Rat	PMID:15194871\|RGD:1642193
Cellular Component	GO:0045202	synapse	GRIN3A	IDA		Human	PMID:17658481
Biological Process	GO:0006816	calcium ion transport	Grin3a	IMP	MGI:MGI:2387963	Mouse	PMID:14507892
Biological Process	GO:0006816	calcium ion transport	Grin3a	IDA		Rat	PMID:17182766\|RGD:8553928
Biological Process	GO:0016358	dendrite development	Grin3a	IMP	MGI:MGI:2387963	Mouse	PMID:9620802
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	Grin3a	IDA		Rat	PMID:16477151\|RGD:1642190
Biological Process	GO:0061000	negative regulation of dendritic spine development	Grin3a	IDA		Rat	PMID:24297929\|RGD:42721994
Biological Process	GO:0060134	prepulse inhibition	Grin3a	IMP	MGI:MGI:2387963	Mouse	PMID:15866554
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Grin3a	IDA		Mouse	PMID:25144876
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Grin3a	IMP		Mouse	PMID:25144876
Biological Process	GO:0045471	response to ethanol	GRIN3A	IDA		Human	PMID:17502428
Biological Process	GO:0045471	response to ethanol	GRIN3A	IDA		Human	PMID:18445116
Biological Process	GO:0048511	rhythmic process	Grin3a	IDA		Rat	PMID:16477151\|RGD:1642190

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.