Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gna13

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GNA13
- Mouse genes Gna13
- Rat genes Gna13
- Zfish genes gna13a,gna13b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gna13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	gna13a	IPI	UniProtKB:Q90Z37	Zfish	PMID:19307601
Molecular Function	GO:0031752	D5 dopamine receptor binding	Gna13	IPI	RGD:2523	Rat	PMID:12623966\|RGD:730287
Molecular Function	GO:0005515	protein binding	GNA13	IPI	UniProtKB:O15085	Human	PMID:10026210
Molecular Function	GO:0005515	protein binding	GNA13	IPI	UniProtKB:Q92888	Human	PMID:12681510
Molecular Function	GO:0005515	protein binding	GNA13	IPI	UniProtKB:Q8NE09	Human	PMID:18703424
Molecular Function	GO:0005515	protein binding	GNA13	IPI	UniProtKB:Q92888	Human	PMID:20300064
Molecular Function	GO:0005515	protein binding	GNA13	IPI	UniProtKB:P32302	Human	PMID:23773523
Molecular Function	GO:0005515	protein binding	GNA13	IPI	UniProtKB:Q5SSG4	Human	PMID:23994616
Molecular Function	GO:0005515	protein binding	Gna13	IPI	UniProtKB:Q9ES67	Mouse	MGI:MGI:5918176\|PMID:18940608
Molecular Function	GO:0005515	protein binding	Gna13	IPI	UniProtKB:O08915	Mouse	MGI:MGI:5508585\|PMID:19390533
Molecular Function	GO:0005515	protein binding	Gna13	IPI	RGD:727957	Rat	PMID:12509430\|RGD:633903
Molecular Function	GO:0005515	protein binding	Gna13	IPI	RGD:2523	Rat	PMID:12623966\|RGD:730287
Cellular Component	GO:0031526	brush border membrane	Gna13	IDA		Rat	PMID:12623966\|RGD:730287
Cellular Component	GO:0005737	cytoplasm	GNA13	IDA		Human	PMID:18703424
Cellular Component	GO:0005737	cytoplasm	Gna13	IDA		Mouse	PMID:18703424
Cellular Component	GO:0005829	cytosol	GNA13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	GNA13	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	GNA13	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	GNA13	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	GNA13	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	GNA13	IDA		Human	PMID:18703424
Cellular Component	GO:0005634	nucleus	Gna13	IDA		Mouse	PMID:18703424
Biological Process	GO:0031584	activation of phospholipase D activity	Gna13	IMP		Rat	PMID:12435801\|RGD:1598460
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Gna13	IGI	MGI:MGI:102891	Mouse	PMID:18541530
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Gna13	IMP		Mouse	MGI:MGI:6158806\|PMID:23229509
Biological Process	GO:0001525	angiogenesis	Gna13	IMP	MGI:MGI:2151775	Mouse	PMID:8999798
Biological Process	GO:0001525	angiogenesis	gna13b	IMP	ZFIN:ZDB-MRPHLNO-110608-2	Zfish	PMID:21113681
Biological Process	GO:0001525	angiogenesis	gna13b	IMP	ZFIN:ZDB-MRPHLNO-110608-3	Zfish	PMID:21113681
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Gna13	IMP	MGI:MGI:2450311,MGI:MGI:3583876	Mouse	PMID:15919816
Biological Process	GO:0030154	cell differentiation	Gna13	IDA		Mouse	PMID:9305907
Biological Process	GO:0042074	cell migration involved in gastrulation	gna13a	IGI	ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:15928205
Biological Process	GO:0042074	cell migration involved in gastrulation	gna13b	IGI	ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:15928205
Biological Process	GO:0060973	cell migration involved in heart development	gna13a	IGI	ZFIN:ZDB-GENE-030131-8277	Zfish	PMID:23318642
Biological Process	GO:0060973	cell migration involved in heart development	gna13a	IGI	ZFIN:ZDB-GENE-030131-8277,ZFIN:ZDB-GENE-050221-1	Zfish	PMID:23318642
Biological Process	GO:0060973	cell migration involved in heart development	gna13b	IGI	ZFIN:ZDB-GENE-030131-5024,ZFIN:ZDB-GENE-050221-1	Zfish	PMID:23318642
Biological Process	GO:0060973	cell migration involved in heart development	gna13b	IGI	ZFIN:ZDB-GENE-030131-5024	Zfish	PMID:23318642
Biological Process	GO:0060026	convergent extension	gna13a	IGI	ZFIN:ZDB-GENE-030131-8277	Zfish	PMID:23318642
Biological Process	GO:0060026	convergent extension	gna13b	IGI	ZFIN:ZDB-GENE-030131-5024	Zfish	PMID:23318642
Biological Process	GO:0003262	endocardial progenitor cell migration to the midline involved in heart field formation	gna13a	IGI	ZFIN:ZDB-GENE-030131-8277	Zfish	PMID:27158029
Biological Process	GO:0003262	endocardial progenitor cell migration to the midline involved in heart field formation	gna13b	IGI	ZFIN:ZDB-GENE-030131-5024	Zfish	PMID:27158029
Biological Process	GO:0007492	endoderm development	gna13a	IGI	ZFIN:ZDB-GENE-030131-8277	Zfish	PMID:23318642
Biological Process	GO:0007492	endoderm development	gna13b	IGI	ZFIN:ZDB-GENE-030131-5024	Zfish	PMID:23318642
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	gna13a	IGI	ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:19307601
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	gna13b	IGI	ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:19307601
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gna13	IMP		Rat	PMID:29453251\|RGD:42721986
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gna13	IMP		Rat	PMID:9092554\|RGD:1582440
Biological Process	GO:0001702	gastrulation with mouth forming second	gna13a	IGI	ZFIN:ZDB-GENO-980202-1408,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:15928205
Biological Process	GO:0001702	gastrulation with mouth forming second	gna13a	IMP		Zfish	PMID:15928205
Biological Process	GO:0001702	gastrulation with mouth forming second	gna13a	IGI	ZFIN:ZDB-GENO-980202-187,ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:15928205
Biological Process	GO:0001702	gastrulation with mouth forming second	gna13b	IMP		Zfish	PMID:15928205
Biological Process	GO:0001702	gastrulation with mouth forming second	gna13b	IGI	ZFIN:ZDB-GENO-980202-187,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:15928205
Biological Process	GO:0030097	hemopoiesis	gna13b	IMP	ZFIN:ZDB-MRPHLNO-110608-2	Zfish	PMID:21113681
Biological Process	GO:0030097	hemopoiesis	gna13b	IMP	ZFIN:ZDB-MRPHLNO-110608-3	Zfish	PMID:21113681
Biological Process	GO:0001701	in utero embryonic development	Gna13	IGI	MGI:MGI:95767	Mouse	PMID:12077299
Biological Process	GO:0035556	intracellular signal transduction	Gna13	IDA		Mouse	PMID:10037795
Biological Process	GO:0048932	myelination of posterior lateral line nerve axons	gna13a	IGI	ZFIN:ZDB-GENO-180713-3,ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:29367382
Biological Process	GO:0048932	myelination of posterior lateral line nerve axons	gna13b	IGI	ZFIN:ZDB-GENO-180713-3,ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:29367382
Biological Process	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	gna13a	IGI	ZFIN:ZDB-GENO-100908-4,ZFIN:ZDB-MRPHLNO-060113-3	Zfish	PMID:19307601
Biological Process	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	Gna13	IMP		Rat	PMID:29453251\|RGD:42721986
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	Gna13	IMP		Rat	PMID:29453251\|RGD:42721986
Biological Process	GO:0014003	oligodendrocyte development	gna13a	IGI	ZFIN:ZDB-GENO-160202-2,ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:25607772
Biological Process	GO:0014003	oligodendrocyte development	gna13b	IGI	ZFIN:ZDB-GENO-160202-2,ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:25607772
Biological Process	GO:0030168	platelet activation	Gna13	IMP	MGI:MGI:2151775	Mouse	PMID:14528298
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Gna13	IMP		Rat	PMID:9092554\|RGD:1582440
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	gna13a	IGI	ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:19307601
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	gna13a	IMP		Zfish	PMID:19307601
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	gna13b	IGI	ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:19307601
Biological Process	GO:0008217	regulation of blood pressure	Gna13	IGI	MGI:MGI:95767	Mouse	PMID:26531127
Biological Process	GO:0008360	regulation of cell shape	Gna13	IDA		Mouse	PMID:10037795
Biological Process	GO:0010762	regulation of fibroblast migration	Gna13	IMP	MGI:MGI:2151775	Mouse	PMID:12077299
Biological Process	GO:0007266	Rho protein signal transduction	Gna13	IDA		Mouse	PMID:10037795
Biological Process	GO:0007266	Rho protein signal transduction	gna13a	IMP		Zfish	PMID:15928205
Biological Process	GO:0007266	Rho protein signal transduction	gna13b	IMP		Zfish	PMID:15928205
Biological Process	GO:0043149	stress fiber assembly	gna13a	IMP		Zfish	PMID:15928205
Biological Process	GO:0043149	stress fiber assembly	gna13b	IMP		Zfish	PMID:15928205
Biological Process	GO:0009826	unidimensional cell growth	gna13a	IGI	ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:15928205
Biological Process	GO:0009826	unidimensional cell growth	gna13b	IGI	ZFIN:ZDB-MRPHLNO-060113-1,ZFIN:ZDB-MRPHLNO-060113-3,ZFIN:ZDB-MRPHLNO-060113-4	Zfish	PMID:15928205

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.