| GO term: | platelet activation |
| Synonym: | blood coagulation, platelet activation |
| GO id: | GO:0030168 |
| Definition: | A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. |
| Number of paths to term: | 8 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological qualityregulation of body fluid levelshemostasisblood coagulationblood coagulation, fibrin clot formation +negative regulation of blood coagulation +platelet activation [GO:0030168] (56 genes, 69 annotations)negative regulation of platelet activationplatelet aggregation +positive regulation of platelet activationregulation of platelet activation +positive regulation of blood coagulation +regulation of blood coagulation +thrombocyte activationbiological_processcellular processsingle-organism cellular processcell activationastrocyte activation +cell activation involved in immune response +chondrocyte activationegg activation +endothelial cell activation +fibroblast activation +follicular dendritic cell activation +keratinocyte activationleukocyte activation +negative regulation of cell activation +neuroblast activationplatelet activation [GO:0030168] (56 genes, 69 annotations)negative regulation of platelet activationplatelet aggregation +positive regulation of platelet activationregulation of platelet activation +positive regulation of cell activation +regulation of cell activation +satellite cell activation +thrombocyte activationbiological_processmulticellular organismal processsingle-multicellular organism processcoagulationblood coagulationblood coagulation, fibrin clot formation +negative regulation of blood coagulation +platelet activation [GO:0030168] (56 genes, 69 annotations)negative regulation of platelet activationplatelet aggregation +positive regulation of platelet activationregulation of platelet activation +positive regulation of blood coagulation +regulation of blood coagulation +thrombocyte activationbiological_processmulticellular organismal processsingle-multicellular organism processregulation of body fluid levelshemostasisblood coagulationblood coagulation, fibrin clot formation +negative regulation of blood coagulation +platelet activation [GO:0030168] (56 genes, 69 annotations)negative regulation of platelet activationplatelet aggregation +positive regulation of platelet activationregulation of platelet activation +positive regulation of blood coagulation +regulation of blood coagulation +thrombocyte activationbiological_processresponse to stimulusresponse to stressresponse to woundingwound healingblood coagulationblood coagulation, fibrin clot formation +negative regulation of blood coagulation +platelet activation [GO:0030168] (56 genes, 69 annotations)negative regulation of platelet activationplatelet aggregation +positive regulation of platelet activationregulation of platelet activation +positive regulation of blood coagulation +regulation of blood coagulation +thrombocyte activationbiological_processsingle-organism processsingle-multicellular organism processcoagulationblood coagulationblood coagulation, fibrin clot formation +negative regulation of blood coagulation +platelet activation [GO:0030168] (56 genes, 69 annotations)negative regulation of platelet activationplatelet aggregation +positive regulation of platelet activationregulation of platelet activation +positive regulation of blood coagulation +regulation of blood coagulation +thrombocyte activationbiological_processsingle-organism processsingle-multicellular organism processregulation of body fluid levelshemostasisblood coagulationblood coagulation, fibrin clot formation +negative regulation of blood coagulation +platelet activation [GO:0030168] (56 genes, 69 annotations)negative regulation of platelet activationplatelet aggregation +positive regulation of platelet activationregulation of platelet activation +positive regulation of blood coagulation +regulation of blood coagulation +thrombocyte activationbiological_processsingle-organism processsingle-organism cellular processcell activationastrocyte activation +cell activation involved in immune response +chondrocyte activationegg activation +endothelial cell activation +fibroblast activation +follicular dendritic cell activation +keratinocyte activationleukocyte activation +negative regulation of cell activation +neuroblast activationplatelet activation [GO:0030168] (56 genes, 69 annotations)negative regulation of platelet activationplatelet aggregation +positive regulation of platelet activationregulation of platelet activation +positive regulation of cell activation +regulation of cell activation +satellite cell activation +thrombocyte activationMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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