Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gata5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GATA5
- Mouse genes Gata5
- Rat genes Gata5
- Zfish genes gata5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gata5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Gata5	IDA		Mouse	MGI:MGI:5009777\|PMID:20855530
Molecular Function	GO:0003677	DNA binding	gata5	IDA		Zfish	PMID:17715064
Molecular Function	GO:0003700	DNA-binding transcription factor activity	GATA5	IDA		Human	PMID:14986113
Molecular Function	GO:0003700	DNA-binding transcription factor activity	gata5	IDA		Zfish	PMID:17715064
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Gata5	IDA		Mouse	MGI:MGI:5286818\|PMID:21633169
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Gata5	IDA		Mouse	PMID:9119112
Molecular Function	GO:0005515	protein binding	GATA5	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GATA5	IPI	UniProtKB:O15496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GATA5	IPI	UniProtKB:P37231	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GATA5	IPI	UniProtKB:P37235	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GATA5	IPI	UniProtKB:P84074	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GATA5	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GATA5	IPI	UniProtKB:Q9Y5V3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gata5	IPI	UniProtKB:Q9ES03	Mouse	MGI:MGI:5284807\|PMID:14550786
Molecular Function	GO:0005515	protein binding	gata5	IPI	UniProtKB:Q9PTQ9	Zfish	PMID:16198294
Molecular Function	GO:0005515	protein binding	gata5	IPI	UniProtKB:Q9DDU3	Zfish	PMID:16198294
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Gata5	IDA		Mouse	PMID:15987774
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	GATA5	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	GATA5	IDA		Human	PMID:9566909
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Gata5	IDA		Mouse	PMID:9119112
Cellular Component	GO:0000785	chromatin	Gata5	IDA		Mouse	MGI:MGI:5286818\|PMID:21633169
Cellular Component	GO:0005634	nucleus	GATA5	IDA		Human	PMID:9566909
Cellular Component	GO:0005634	nucleus	gata5	IDA		Zfish	PMID:28285006
Biological Process	GO:0003180	aortic valve morphogenesis	GATA5	IMP		Human	PMID:22641149
Biological Process	GO:0003180	aortic valve morphogenesis	GATA5	IMP		Human	PMID:24638895
Biological Process	GO:0003180	aortic valve morphogenesis	Gata5	IMP		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0055007	cardiac muscle cell differentiation	gata5	IMP	ZFIN:ZDB-MRPHLNO-060522-2	Zfish	PMID:28285006
Biological Process	GO:0055007	cardiac muscle cell differentiation	gata5	IMP	ZFIN:ZDB-MRPHLNO-080325-5	Zfish	PMID:28285006
Biological Process	GO:0055007	cardiac muscle cell differentiation	gata5	IGI	ZFIN:ZDB-MRPHLNO-060328-2,ZFIN:ZDB-MRPHLNO-060522-2,ZFIN:ZDB-MRPHLNO-070409-1	Zfish	PMID:21715426
Biological Process	GO:0060975	cardioblast migration to the midline involved in heart field formation	gata5	IGI	ZFIN:ZDB-MRPHLNO-050927-1,ZFIN:ZDB-MRPHLNO-060522-2	Zfish	PMID:19297410
Biological Process	GO:0003318	cell migration to the midline involved in heart development	gata5	IMP	ZFIN:ZDB-CRISPR-131024-2	Zfish	PMID:23528705
Biological Process	GO:0071773	cellular response to BMP stimulus	Gata5	IDA		Mouse	PMID:20501701
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Gata5	IEP		Rat	PMID:25726415\|RGD:155260369
Biological Process	GO:0071732	cellular response to nitric oxide	Gata5	IEP		Rat	PMID:25726415\|RGD:155260369
Biological Process	GO:0006351	DNA-templated transcription	Gata5	IDA		Mouse	MGI:MGI:86313\|PMID:9119112
Biological Process	GO:0003143	embryonic heart tube morphogenesis	gata5	IMP	ZFIN:ZDB-MRPHLNO-060522-2	Zfish	PMID:28180938
Biological Process	GO:0003274	endocardial cushion fusion	Gata5	IMP		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0007492	endoderm development	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:10580005
Biological Process	GO:0007492	endoderm development	gata5	IMP	ZFIN:ZDB-GENO-000621-2	Zfish	PMID:10580005
Biological Process	GO:0001706	endoderm formation	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:11092818
Biological Process	GO:0001706	endoderm formation	gata5	IGI	ZFIN:ZDB-GENE-000208-20,ZFIN:ZDB-GENE-001228-1	Zfish	PMID:16198294
Biological Process	GO:0001706	endoderm formation	gata5	IGI	ZFIN:ZDB-GENE-000208-20	Zfish	PMID:16198294
Biological Process	GO:0001706	endoderm formation	gata5	IGI	ZFIN:ZDB-GENO-110502-3	Zfish	PMID:11092818
Biological Process	GO:0001706	endoderm formation	gata5	IGI	ZFIN:ZDB-GENE-000208-20,ZFIN:ZDB-GENE-001228-1,ZFIN:ZDB-MRPHLNO-050818-2	Zfish	PMID:16198294
Biological Process	GO:0010467	gene expression	gata5	IGI	ZFIN:ZDB-GENE-000622-1	Zfish	PMID:30593510
Biological Process	GO:0010467	gene expression	gata5	IMP	ZFIN:ZDB-MRPHLNO-060522-2,ZFIN:ZDB-MRPHLNO-050927-1	Zfish	PMID:30593510
Biological Process	GO:0007507	heart development	Gata5	IDA		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0007507	heart development	gata5	IMP	ZFIN:ZDB-GENO-000621-2	Zfish	PMID:10580005
Biological Process	GO:0007507	heart development	gata5	IMP	ZFIN:ZDB-MRPHLNO-060522-2	Zfish	PMID:15786591
Biological Process	GO:0007507	heart development	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:10580005
Biological Process	GO:0007507	heart development	gata5	IMP		Zfish	PMID:17715064
Biological Process	GO:0003007	heart morphogenesis	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:9007249
Biological Process	GO:0003007	heart morphogenesis	gata5	IGI	ZFIN:ZDB-MRPHLNO-060328-2,ZFIN:ZDB-MRPHLNO-060522-2,ZFIN:ZDB-MRPHLNO-070409-1	Zfish	PMID:21715426
Biological Process	GO:0003007	heart morphogenesis	gata5	IMP	ZFIN:ZDB-MRPHLNO-060522-2	Zfish	PMID:17869240
Biological Process	GO:0060575	intestinal epithelial cell differentiation	GATA5	IDA		Human	PMID:9566909
Biological Process	GO:0070121	Kupffer's vesicle development	gata5	IMP	ZFIN:ZDB-MRPHLNO-080325-5	Zfish	PMID:21447552
Biological Process	GO:0060972	left/right pattern formation	gata5	IMP	ZFIN:ZDB-MRPHLNO-080325-5	Zfish	PMID:21447552
Biological Process	GO:0001889	liver development	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:11092818
Biological Process	GO:0030099	myeloid cell differentiation	gata5	IGI	ZFIN:ZDB-MRPHLNO-050927-1,ZFIN:ZDB-MRPHLNO-060522-2	Zfish	PMID:19297410
Biological Process	GO:0043011	myeloid dendritic cell differentiation	gata5	IMP		Zfish	PMID:30593510
Biological Process	GO:0043011	myeloid dendritic cell differentiation	gata5	IMP	ZFIN:ZDB-GENO-200217-4	Zfish	PMID:30593510
Biological Process	GO:0043011	myeloid dendritic cell differentiation	gata5	IGI	ZFIN:ZDB-GENE-980526-340,ZFIN:ZDB-GENE-000622-1	Zfish	PMID:30593510
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	Gata5	IMP		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0010629	negative regulation of gene expression	Gata5	IMP		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0031016	pancreas development	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:11092818
Biological Process	GO:1902512	positive regulation of apoptotic DNA fragmentation	Gata5	IMP		Rat	PMID:25726415\|RGD:155260369
Biological Process	GO:0062000	positive regulation of cardiac endothelial to mesenchymal transition	Gata5	IMP		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Gata5	IDA		Mouse	PMID:9119112
Biological Process	GO:0010628	positive regulation of gene expression	Gata5	IMP		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	Gata5	IMP		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GATA5	IDA		Human	PMID:14986113
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Gata5	IDA		Mouse	MGI:MGI:5286818\|PMID:21633169
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	gata5	IGI	ZFIN:ZDB-MRPHLNO-050927-1,ZFIN:ZDB-MRPHLNO-060522-2,ZFIN:ZDB-MRPHLNO-110124-1	Zfish	PMID:19441085
Biological Process	GO:0048618	post-embryonic foregut morphogenesis	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:12618131
Biological Process	GO:0006355	regulation of DNA-templated transcription	Gata5	IDA		Mouse	PMID:9738004
Biological Process	GO:0010468	regulation of gene expression	gata5	IDA		Zfish	PMID:28285006
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Gata5	IDA		Mouse	MGI:MGI:86313\|PMID:9119112
Biological Process	GO:0048538	thymus development	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:11092818
Biological Process	GO:0030878	thyroid gland development	gata5	IMP	ZFIN:ZDB-GENO-980202-853	Zfish	PMID:11092818

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.