Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Foxm1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FOXM1
- Mouse genes Foxm1
- Rat genes Foxm1
- Zfish genes foxm1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Foxm1	IDA		Rat	PMID:9242644\|RGD:61588
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:P24864	Human	PMID:16504183
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:O43524	Human	PMID:16809346
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:P35222	Human	PMID:22014570
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:O00541	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:O75152	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:P14868	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:Q13416	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:Q8N9N5-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:Q8N9N5-7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	FOXM1	IPI	UniProtKB:A0A455ZAR2	Human	PMID:33754036
Molecular Function	GO:0005515	protein binding	Foxm1	IPI	UniProtKB:P03129	Mouse	MGI:MGI:3687658\|PMID:10523841
Molecular Function	GO:0019901	protein kinase binding	FOXM1	IPI	UniProtKB:P53350	Human	PMID:19160488
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOXM1	IDA		Human	PMID:21860419
Molecular Function	GO:0043565	sequence-specific DNA binding	Foxm1	IDA		Rat	PMID:9242644\|RGD:61588
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Foxm1	IDA		Mouse	PMID:17261592
Cellular Component	GO:0005634	nucleus	Foxm1	IDA		Mouse	PMID:17261592
Biological Process	GO:0008283	cell population proliferation	Foxm1	IMP	MGI:MGI:3522201	Mouse	PMID:15817462
Biological Process	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	FOXM1	IMP		Human	PMID:17101782
Biological Process	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Foxm1	IMP		Mouse	MGI:MGI:3698692\|PMID:17101782
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	FOXM1	IDA		Human	PMID:19160488
Biological Process	GO:0001889	liver development	Foxm1	IMP	MGI:MGI:3522201	Mouse	PMID:15531365
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXM1	IMP		Human	PMID:20531406
Biological Process	GO:0032873	negative regulation of stress-activated MAPK cascade	FOXM1	IMP		Human	PMID:19696738
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FOXM1	IMP		Human	PMID:20531406
Biological Process	GO:0008284	positive regulation of cell population proliferation	FOXM1	IMP		Human	PMID:19696738
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXM1	IMP		Human	PMID:17101782
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXM1	IMP		Human	PMID:20531406
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Foxm1	IMP		Mouse	MGI:MGI:3698692\|PMID:17101782
Biological Process	GO:2000781	positive regulation of double-strand break repair	FOXM1	IMP		Human	PMID:17101782
Biological Process	GO:2000781	positive regulation of double-strand break repair	Foxm1	IMP		Mouse	MGI:MGI:3698692\|PMID:17101782
Biological Process	GO:2000648	positive regulation of stem cell proliferation	Foxm1	IMP	MGI:MGI:3522201	Mouse	PMID:15817462
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXM1	IDA		Human	PMID:19160488
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXM1	IMP		Human	PMID:20531406
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxm1	IDA		Mouse	PMID:17261592
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxm1	IDA		Mouse	PMID:15817462
Biological Process	GO:0051726	regulation of cell cycle	FOXM1	IMP		Human	PMID:19696738
Biological Process	GO:0042127	regulation of cell population proliferation	Foxm1	IMP	MGI:MGI:3522201	Mouse	PMID:15531365
Biological Process	GO:0046578	regulation of Ras protein signal transduction	FOXM1	IMP		Human	PMID:19696738
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	FOXM1	IMP		Human	PMID:19696738
Biological Process	GO:0051591	response to cAMP	Foxm1	IEP		Rat	PMID:10919260\|RGD:2315098
Biological Process	GO:0034698	response to gonadotropin	Foxm1	IEP		Rat	PMID:10919260\|RGD:2315098
Biological Process	GO:0072089	stem cell proliferation	Foxm1	IMP	MGI:MGI:3522201	Mouse	PMID:15817462
Biological Process	GO:0001570	vasculogenesis	Foxm1	IMP	MGI:MGI:3522201	Mouse	PMID:15817462

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.