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Gene Ontology Browser
Term Detail
GO term:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO id:GO:0006978
Definition:A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
Number of paths to term: 33

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction in response to DNA damage
                                                                is-aDNA damage response, signal transduction by p53 class mediator
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction in response to DNA damage
                                                                is-aDNA damage response, signal transduction resulting in transcription
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to DNA damage stimulus
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to DNA damage stimulus
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction by p53 class mediator
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction by p53 class mediator
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction in response to DNA damage
                                                                is-aDNA damage response, signal transduction by p53 class mediator
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction in response to DNA damage
                                                                is-aDNA damage response, signal transduction resulting in transcription
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction by p53 class mediator
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to DNA damage stimulus
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to stress
                                        is-acellular response to DNA damage stimulus
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction by p53 class mediator
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-acellular response to stress
                                        is-acellular response to DNA damage stimulus
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-acellular response to stress
                                        is-acellular response to DNA damage stimulus
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction by p53 class mediator
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction by p53 class mediator
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-asignal transduction in response to DNA damage
                                                        is-aDNA damage response, signal transduction resulting in transcription
                                                                is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction by p53 class mediator
                                                                is-aDNA damage response, signal transduction by p53 class mediator
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction in response to DNA damage
                                                                is-aDNA damage response, signal transduction by p53 class mediator
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +
                                                                        negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator +
                                                                        regulatesregulation of DNA damage response, signal transduction by p53 class mediator +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-asignal transduction in response to DNA damage
                                                                is-aDNA damage response, signal transduction resulting in transcription
                                                                        is-aDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                positively-regulatespositive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
                                                                                regulatesregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory