Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes C1QB
  • Mouse genes C1qb
  • Rat genes C1qb
  • Zfish genes c1qb,c1qc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set C1qb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	C1qb	IPI	PR:P14106	Mouse	PMID:10964938
Molecular Function	GO:0005515	protein binding	C1QB	IPI	UniProtKB:P02745	Human	PMID:12960167
Molecular Function	GO:0005515	protein binding	C1QB	IPI	UniProtKB:P02745	Human	PMID:21054788
Molecular Function	GO:0005515	protein binding	C1QB	IPI	UniProtKB:Q07021:PRO_0000018590	Human	PMID:28018340
Molecular Function	GO:0005515	protein binding	C1QB	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	C1QB	IPI	UniProtKB:P02745	Human	PMID:7240
Cellular Component	GO:0072562	blood microparticle	C1QB	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	C1QB	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	C1QB	HDA		Human	PMID:28675934
Cellular Component	GO:0005602	complement component C1 complex	C1qb	IDA		Rat	PMID:7594503|RGD:69784
Cellular Component	GO:0062167	complement component C1q complex	C1QB	IPI		Human	PMID:29449492
Cellular Component	GO:0005576	extracellular region	C1QB	IDA		Human	PMID:18250442
Cellular Component	GO:0005615	extracellular space	C1qb	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0098794	postsynapse	C1qb	IGI	ComplexPortal:CPX-1180,UniProtKB:P98086,UniProtKB:Q02105	Mouse	MGI:MGI:6275119|PMID:27033548
Cellular Component	GO:0045202	synapse	C1qb	IGI	UniProtKB:P98086,UniProtKB:Q02105	Mouse	MGI:MGI:3801262|PMID:18083105
Cellular Component	GO:0045202	synapse	C1qb	IDA		Mouse	MGI:MGI:3801262|PMID:18083105
Cellular Component	GO:0045202	synapse	C1qb	IDA		Rat	PMID:18083105|RGD:13838802
Biological Process	GO:0007420	brain development	C1qb	IEP		Rat	PMID:7955342|RGD:1599516
Biological Process	GO:0006958	complement activation, classical pathway	C1QB	IDA		Human	PMID:29449492
Biological Process	GO:0006958	complement activation, classical pathway	c1qb	IDA		Zfish	PMID:20615881
Biological Process	GO:0006958	complement activation, classical pathway	c1qc	IDA		Zfish	PMID:20615881
Biological Process	GO:0048839	inner ear development	C1qb	IDA		Mouse	PMID:21795542
Biological Process	GO:0051384	response to glucocorticoid	C1qb	IEP		Rat	PMID:9214457|RGD:1599512
Biological Process	GO:0010033	response to organic substance	C1qb	IEP		Rat	PMID:7870303|RGD:1599514
Biological Process	GO:0098883	synapse pruning	C1qb	IGI	UniProtKB:P98086,UniProtKB:Q02105	Mouse	MGI:MGI:6275119|PMID:27033548

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern