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Gene Ontology Browser
Term Detail
GO term:blood microparticle
Synonym: cell membrane microparticle
GO id:GO:0072562
Definition:A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
CommentsNote that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-aextracellular region
                        part-ofextracellular region part
                                is-aactivin complex +
                                is-aanchoring collagen complex +
                                is-aangiogenin-PRI complex
                                is-aapical lamina of hyaline layer
                                is-aapoptotic body
                                is-abasal lamina +
                                is-abasement membrane +
                                is-abasement membrane collagen trimer +
                                is-ablood microparticle [GO:0072562] (104 genes, 104 annotations)
                                        is-aendothelial microparticle
                                is-abursicon neuropeptide hormone complex
                                is-aclassical-complement-pathway C3/C5 convertase complex
                                is-aCNTFR-CLCF1 complex
                                is-acollagen and cuticulin-based cuticle extracellular matrix part +
                                is-acollagen type IV trimer
                                is-acollagen type XIX trimer
                                is-acollagen type XV trimer
                                is-acollagen type XXVI trimer
                                is-acollagen type XXVII trimer
                                is-acollagen type XXVIII trimer
                                is-acomplement component C1 complex
                                is-aCRLF-CLCF1 complex
                                is-aextra-invasive hyphal space
                                is-aextracellular ferritin complex
                                is-aextracellular isoamylase complex
                                is-aextracellular organelle +
                                is-aextracellular space +
                                is-aextracellular space of host +
                                is-aextrahaustorial matrix
                                is-aextraorganismal space +
                                is-afemale germline ring canal inner rim
                                is-afemale germline ring canal outer rim
                                is-afibril +
                                is-afibrillar collagen trimer +
                                is-afibrinogen complex
                                is-afollicle-stimulating hormone complex
                                is-ahyaluranon cable
                                is-aimmunoglobulin complex, circulating +
                                is-ainhibin complex +
                                is-ainsulin-like growth factor binding protein complex +
                                is-aintercellular bridge +
                                is-ainterleukin-12 complex
                                is-ainterleukin-23 complex
                                is-ainterleukin-27 complex
                                is-ainterleukin-35 complex
                                is-alamina densa
                                is-alamina lucida
                                is-alamina reticularis
                                is-alaminin complex +
                                is-alarval serum protein complex
                                is-amucus layer +
                                is-aother organism part +
                                is-aplasma lipoprotein particle +
                                is-aproteinaceous extracellular matrix +
                                is-ascaffoldin complex
                                is-asheet-forming collagen trimer +
                                is-asublamina densa
                                is-aVEGF-A complex


Gene_Ontology
        is-acellular_component
                is-aextracellular region
                        part-ofextracellular region part
                                is-aextracellular space
                                        part-ofactivin complex +
                                        part-ofblood microparticle [GO:0072562] (104 genes, 104 annotations)
                                                is-aendothelial microparticle
                                        part-ofbursicon neuropeptide hormone complex
                                        part-ofclassical-complement-pathway C3/C5 convertase complex
                                        part-ofCNTFR-CLCF1 complex
                                        part-ofcomplement component C1 complex
                                        part-ofCRLF-CLCF1 complex
                                        part-offibrinogen complex
                                        part-ofimmunoglobulin complex, circulating +
                                        part-ofinhibin complex +
                                        part-ofinsulin-like growth factor binding protein complex +
                                        part-ofinterleukin-12 complex
                                        part-ofinterleukin-23 complex
                                        part-ofinterleukin-27 complex
                                        part-ofinterleukin-35 complex
                                        part-oflarval serum protein complex
                                        part-ofplasma lipoprotein particle +


Gene_Ontology
        is-acellular_component
                is-aextracellular region part
                        is-aactivin complex +
                        is-aanchoring collagen complex +
                        is-aangiogenin-PRI complex
                        is-aapical lamina of hyaline layer
                        is-aapoptotic body
                        is-abasal lamina +
                        is-abasement membrane +
                        is-abasement membrane collagen trimer +
                        is-ablood microparticle [GO:0072562] (104 genes, 104 annotations)
                                is-aendothelial microparticle
                        is-abursicon neuropeptide hormone complex
                        is-aclassical-complement-pathway C3/C5 convertase complex
                        is-aCNTFR-CLCF1 complex
                        is-acollagen and cuticulin-based cuticle extracellular matrix part +
                        is-acollagen type IV trimer
                        is-acollagen type XIX trimer
                        is-acollagen type XV trimer
                        is-acollagen type XXVI trimer
                        is-acollagen type XXVII trimer
                        is-acollagen type XXVIII trimer
                        is-acomplement component C1 complex
                        is-aCRLF-CLCF1 complex
                        is-aextra-invasive hyphal space
                        is-aextracellular ferritin complex
                        is-aextracellular isoamylase complex
                        is-aextracellular organelle +
                        is-aextracellular space +
                        is-aextracellular space of host +
                        is-aextrahaustorial matrix
                        is-aextraorganismal space +
                        is-afemale germline ring canal inner rim
                        is-afemale germline ring canal outer rim
                        is-afibril +
                        is-afibrillar collagen trimer +
                        is-afibrinogen complex
                        is-afollicle-stimulating hormone complex
                        is-ahyaluranon cable
                        is-aimmunoglobulin complex, circulating +
                        is-ainhibin complex +
                        is-ainsulin-like growth factor binding protein complex +
                        is-aintercellular bridge +
                        is-ainterleukin-12 complex
                        is-ainterleukin-23 complex
                        is-ainterleukin-27 complex
                        is-ainterleukin-35 complex
                        is-alamina densa
                        is-alamina lucida
                        is-alamina reticularis
                        is-alaminin complex +
                        is-alarval serum protein complex
                        is-amucus layer +
                        is-aother organism part +
                        is-aplasma lipoprotein particle +
                        is-aproteinaceous extracellular matrix +
                        is-ascaffoldin complex
                        is-asheet-forming collagen trimer +
                        is-asublamina densa
                        is-aVEGF-A complex


Gene_Ontology
        is-acellular_component
                is-aextracellular region part
                        is-aextracellular space
                                part-ofactivin complex +
                                part-ofblood microparticle [GO:0072562] (104 genes, 104 annotations)
                                        is-aendothelial microparticle
                                part-ofbursicon neuropeptide hormone complex
                                part-ofclassical-complement-pathway C3/C5 convertase complex
                                part-ofCNTFR-CLCF1 complex
                                part-ofcomplement component C1 complex
                                part-ofCRLF-CLCF1 complex
                                part-offibrinogen complex
                                part-ofimmunoglobulin complex, circulating +
                                part-ofinhibin complex +
                                part-ofinsulin-like growth factor binding protein complex +
                                part-ofinterleukin-12 complex
                                part-ofinterleukin-23 complex
                                part-ofinterleukin-27 complex
                                part-ofinterleukin-35 complex
                                part-oflarval serum protein complex
                                part-ofplasma lipoprotein particle +


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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory