C1qb
Gene Detail

Symbol Name ID

C1qb complement component 1, q subcomponent, beta polypeptide MGI:88224

Feature Type

protein coding gene

Genetic Map

Chromosome 4

69.05 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr4:136880129-136886187 bp, - strand From VEGA annotation of GRCm38   6059 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:418  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: complement subcomponent C1q chain A
Gene Tree: C1qb

Human homologs

Human Homolog		C1QB, complement component 1, q subcomponent, B chain
NCBI Gene ID		713
neXtProt AC		NX_P02746
Human Chr (Location)		1p36.12; chr1:22979682-22988029 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human C1QB

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	complement activation, classical pathway, innate immune response, ...
Component	collagen, complement component C1 complex, ...
Function	protein homodimerization activity

External Resources: FuncBase

Expression

cDNA source data(120)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(123) Genomic(2) cDNA(121)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000009766 (Evidence)
Ensembl Gene Model	ENSMUSG00000036905 (Evidence)
Entrez Gene	12260 (Evidence)
UniGene	2570
DFCI	TC1572610, TC1759693
DoTS	DT.97405765
NIA Mouse Gene Index	U025672
Consensus CDS Project	CCDS18810.1
International Mouse Knockout Project Status	C1qb

Sequences

Length	Strain/Species
genomic	OTTMUSG00000009766	VEGA Gene Model | MGI Sequence Detail	6059	C57BL/6J
transcript	OTTMUST00000022610	VEGA | MGI Sequence Detail	1088	Not Applicable
polypeptide	OTTMUSP00000010322	VEGA | MGI Sequence Detail	253	Not Applicable

All sequences(28) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(2) : SNPs(46 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR008160	Collagen triple helix repeat
InterPro	IPR001073	Complement C1q protein
InterPro	IPR008983	Tumour necrosis factor-like
Protein Ontology	PR:000004876	complement C1q subcomponent subunit B

References

(Earliest) J:10130 Petry F, et al., Molecular cloning and characterization of the complementary DNA coding for the B-chain of murine Clq. FEBS Lett. 1989 Nov 20;258(1):89-93
(Latest) J:174607 Lu CC, et al., Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly. J Neurosci. 2011 Jul 27;31(30):10903-18
All references(38)

Other accession IDs

MGD-MRK-1697