Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCL11B
  • Mouse genes Bcl11b
  • Rat genes Bcl11b
  • Zfish genes bcl11ba,bcl11bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcl11b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Bcl11b	IDA		Mouse	PMID:18595722
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Bcl11b	IDA		Mouse	PMID:19251658
Molecular Function	GO:0005515	protein binding	BCL11B	IPI	UniProtKB:O43463	Human	PMID:17245431
Molecular Function	GO:0005515	protein binding	BCL11B	IPI	UniProtKB:Q13547	Human	PMID:17245431
Molecular Function	GO:0005515	protein binding	BCL11B	IPI	UniProtKB:Q92769	Human	PMID:17245431
Molecular Function	GO:0005515	protein binding	BCL11B	IPI	UniProtKB:Q13547	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	BCL11B	IPI	UniProtKB:Q92769	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	Bcl11b	IPI	PR:P42859	Mouse	PMID:18595722
Molecular Function	GO:0005515	protein binding	Bcl11b	IPI	PR:B2RWS6	Mouse	PMID:16809611
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Bcl11b	IDA		Mouse	PMID:16809611
Molecular Function	GO:0043565	sequence-specific DNA binding	Bcl11b	IDA		Mouse	PMID:16809611
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	BCL11B	IDA		Human	PMID:28473536
Cellular Component	GO:0005622	intracellular anatomical structure	Bcl11b	IDA		Mouse	PMID:18255031
Cellular Component	GO:0043005	neuron projection	Bcl11b	IDA		Mouse	PMID:25100583
Cellular Component	GO:0005634	nucleus	Bcl11b	IDA		Mouse	PMID:12565905
Cellular Component	GO:0005634	nucleus	Bcl11b	IDA		Mouse	PMID:21752992
Cellular Component	GO:0016514	SWI/SNF complex	BCL11B	IDA		Human	PMID:23644491
Cellular Component	GO:0016514	SWI/SNF complex	Bcl11b	IDA		Mouse	MGI:MGI:6810794|PMID:23644491
Biological Process	GO:0046632	alpha-beta T cell differentiation	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0006915	apoptotic process	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0007409	axonogenesis	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:15664173
Biological Process	GO:0021953	central nervous system neuron differentiation	Bcl11b	IGI	MGI:MGI:1352456	Mouse	PMID:18215621
Biological Process	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	Bcl11b	IGI	MGI:MGI:2679336	Mouse	PMID:23144223
Biological Process	GO:0003382	epithelial cell morphogenesis	Bcl11b	IMP	MGI:MGI:3839578	Mouse	PMID:19251658
Biological Process	GO:0035701	hematopoietic stem cell migration	BCL11B	IMP		Human	PMID:27959755
Biological Process	GO:0003334	keratinocyte development	Bcl11b	IMP	MGI:MGI:3839576	Mouse	PMID:19092943
Biological Process	GO:0003334	keratinocyte development	Bcl11b	IMP	MGI:MGI:3839578	Mouse	PMID:19092943
Biological Process	GO:0097535	lymphoid lineage cell migration into thymus	BCL11B	IMP		Human	PMID:27959755
Biological Process	GO:0008285	negative regulation of cell population proliferation	Bcl11b	IDA		Mouse	PMID:12565905
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0070244	negative regulation of thymocyte apoptotic process	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:16670294
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Bcl11b	IMP	MGI:MGI:3839578	Mouse	PMID:19251658
Biological Process	GO:0071678	olfactory bulb axon guidance	Bcl11b	IMP		Mouse	PMID:21752992
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	BCL11B	IMP		Human	PMID:16809611
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bcl11b	IMP	MGI:MGI:3839578	Mouse	PMID:19251658
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bcl11b	IGI	MGI:MGI:88327	Mouse	PMID:16809611
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bcl11b	IDA		Mouse	PMID:18595722
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bcl11b	IDA		Mouse	PMID:16809611
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0043368	positive T cell selection	Bcl11b	IMP	MGI:MGI:3767620	Mouse	PMID:17998389
Biological Process	GO:0031077	post-embryonic camera-type eye development	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0009791	post-embryonic development	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0010468	regulation of gene expression	Bcl11b	IMP		Mouse	PMID:21752992
Biological Process	GO:0010837	regulation of keratinocyte proliferation	Bcl11b	IMP	MGI:MGI:3839578	Mouse	PMID:19092943
Biological Process	GO:0019216	regulation of lipid metabolic process	Bcl11b	IMP	MGI:MGI:3839576	Mouse	PMID:19092943
Biological Process	GO:0019216	regulation of lipid metabolic process	Bcl11b	IMP	MGI:MGI:3839578	Mouse	PMID:19092943
Biological Process	GO:0045664	regulation of neuron differentiation	Bcl11b	IMP		Mouse	PMID:21752992
Biological Process	GO:0043588	skin development	Bcl11b	IMP	MGI:MGI:3839576	Mouse	PMID:19092943
Biological Process	GO:0021773	striatal medium spiny neuron differentiation	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:18199763
Biological Process	GO:0070231	T cell apoptotic process	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0033077	T cell differentiation in thymus	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:16670294
Biological Process	GO:0033153	T cell receptor V(D)J recombination	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0070242	thymocyte apoptotic process	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:16670294
Biological Process	GO:0048538	thymus development	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0006366	transcription by RNA polymerase II	Bcl11b	IMP	MGI:MGI:3839578	Mouse	PMID:19251658
Biological Process	GO:0006366	transcription by RNA polymerase II	Bcl11b	IMP	MGI:MGI:2663971	Mouse	PMID:12717433
Biological Process	GO:0006366	transcription by RNA polymerase II	Bcl11b	IDA		Mouse	PMID:16809611
Biological Process	GO:0006366	transcription by RNA polymerase II	Bcl11b	IGI	MGI:MGI:88327	Mouse	PMID:16809611

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern