Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes BCL11A
  • Mouse genes Bcl11a
  • Rat genes Bcl11a
  • Zfish genes bcl11aa,bcl11ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Bcl11a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	BCL11A	IDA		Human	PMID:19153051
Molecular Function	GO:0005515	protein binding	Bcl11a	IPI	UniProtKB:O54714	Mouse	MGI:MGI:3820475|PMID:18681895
Molecular Function	GO:0019901	protein kinase binding	Bcl11a	IPI	RGD:62004	Rat	PMID:20623620|RGD:11100016
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	BCL11A	IDA		Human	PMID:19153051
Molecular Function	GO:0003714	transcription corepressor activity	Bcl11a	IDA		Mouse	PMID:10744719
Cellular Component	GO:0005737	cytoplasm	Bcl11a	IDA		Rat	PMID:17455301|RGD:11100019
Cellular Component	GO:0016604	nuclear body	Bcl11a	IDA		Mouse	MGI:MGI:3820475|PMID:18681895
Cellular Component	GO:0005654	nucleoplasm	BCL11A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Bcl11a	IDA		Mouse	PMID:10744719
Cellular Component	GO:0005634	nucleus	Bcl11a	IDA		Rat	PMID:20623620|RGD:11100016
Cellular Component	GO:0098794	postsynapse	Bcl11a	IDA		Rat	PMID:17455301|RGD:11100019
Cellular Component	GO:0014069	postsynaptic density	Bcl11a	IDA		Rat	PMID:17455301|RGD:11100019
Cellular Component	GO:0016514	SWI/SNF complex	BCL11A	IDA		Human	PMID:23644491
Cellular Component	GO:0016514	SWI/SNF complex	Bcl11a	IDA		Mouse	MGI:MGI:6810794|PMID:23644491
Biological Process	GO:0030183	B cell differentiation	Bcl11a	IMP	MGI:MGI:2663941	Mouse	PMID:12717432
Biological Process	GO:0007420	brain development	bcl11aa	IMP	ZFIN:ZDB-MRPHLNO-161206-6	Zfish	PMID:27699255
Biological Process	GO:0007420	brain development	bcl11ab	IMP	ZFIN:ZDB-MRPHLNO-161206-7	Zfish	PMID:27699255
Biological Process	GO:1905232	cellular response to L-glutamate	Bcl11a	IEP		Rat	PMID:20534004|RGD:11100020
Biological Process	GO:0010467	gene expression	Bcl11a	IMP	MGI:MGI:4358088	Mouse	PMID:19657335
Biological Process	GO:2000173	negative regulation of branching morphogenesis of a nerve	Bcl11a	IMP		Rat	PMID:19616629|RGD:11100018
Biological Process	GO:2000171	negative regulation of dendrite development	Bcl11a	IMP		Rat	PMID:19616629|RGD:11100018
Biological Process	GO:1903860	negative regulation of dendrite extension	Bcl11a	IMP		Rat	PMID:19616629|RGD:11100018
Biological Process	GO:0010629	negative regulation of gene expression	Bcl11a	IMP	MGI:MGI:4358088	Mouse	PMID:19657335
Biological Process	GO:1904800	negative regulation of neuron remodeling	Bcl11a	IMP		Rat	PMID:19616629|RGD:11100018
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	BCL11A	IDA		Human	PMID:19153051
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Bcl11a	IMP		Mouse	MGI:MGI:6153398|PMID:29606353
Biological Process	GO:0010628	positive regulation of gene expression	Bcl11a	IMP		Rat	PMID:19616629|RGD:11100018
Biological Process	GO:0016925	protein sumoylation	Bcl11a	IMP		Mouse	MGI:MGI:3820475|PMID:18681895
Biological Process	GO:0030217	T cell differentiation	Bcl11a	IMP	MGI:MGI:2663941	Mouse	PMID:12717432

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern