Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAMTS4
  • Mouse genes Adamts4
  • Rat genes Adamts4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adamts4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004222	metalloendopeptidase activity	Adamts4	IDA		Mouse	PMID:23684986
Molecular Function	GO:0008237	metallopeptidase activity	ADAMTS4	IDA		Human	PMID:21370305
Molecular Function	GO:0008237	metallopeptidase activity	Adamts4	IDA		Mouse	PMID:15192113
Molecular Function	GO:0008233	peptidase activity	ADAMTS4	IDA		Human	PMID:23845380
Molecular Function	GO:0002020	protease binding	ADAMTS4	IPI	UniProtKB:P09958	Human	PMID:14744861
Molecular Function	GO:0005515	protein binding	ADAMTS4	IPI	UniProtKB:O60687	Human	PMID:18718938
Molecular Function	GO:0005515	protein binding	Adamts4	IPI	PR:Q62507	Mouse	PMID:23684986
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ADAMTS4	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Adamts4	HDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:0005615	extracellular space	ADAMTS4	IDA		Human	PMID:14744861
Cellular Component	GO:0016607	nuclear speck	ADAMTS4	IDA		Human	GO_REF:0000052
Biological Process	GO:0042742	defense response to bacterium	Adamts4	IGI	MGI:MGI:1346321	Mouse	PMID:23684986
Biological Process	GO:0006508	proteolysis	Adamts4	IDA		Mouse	PMID:23684986
Biological Process	GO:0006508	proteolysis	Adamts4	IDA		Mouse	PMID:15192113
Biological Process	GO:0044691	tooth eruption	Adamts4	IEP		Rat	PMID:16200461|RGD:9684848

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern