| GO term: | metalloendopeptidase activity |
| Synonym: | metalloendoprotease activity |
| Synonym: | metalloendoproteinase activity |
| GO id: | GO:0004222 |
| Definition: | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activityhydrolase activitypeptidase activitypeptidase activity, acting on L-amino acid peptidesendopeptidase activityaspartic-type endopeptidase activity +cysteine-type endopeptidase activity +glutamic-type endopeptidase activitymetalloendopeptidase activity [GO:0004222] (97 genes, 105 annotations)serine-type endopeptidase activitythreonine-type endopeptidase activitymolecular_functioncatalytic activityhydrolase activitypeptidase activitypeptidase activity, acting on L-amino acid peptidesmetallopeptidase activitymetalloendopeptidase activity [GO:0004222] (97 genes, 105 annotations)metalloexopeptidase activity +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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