Excel File Text File All mouse models of melanoma with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      melanoma Braftm1Cpri/Braftm1Cpri
Tg(Tyr-cre/ERT2)1Lru/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 J:147434 View
      skin melanoma Grm1Tg(p18A4.B)1352Szc/0 Not Specified J:83183 View
skin melanoma Tg(Dct-Grm1)ESzc/0 involves: C57BL/6J J:83183 View
uveal melanoma Tg(Dct-Grm1)ESzc/0 C57BL/6J-Tg(Dct-Grm1)ESzc J:230115 View
      melanoma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Ptentm1Rps/Ptentm1Rps
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129/Sv * C57BL/6J * FVB * SJL J:155731 View
melanoma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Ptentm1Rps/Ptentm1Rps
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129/Sv * 129S1/Sv * C57BL/6J * FVB/N * SJL J:155731 View
melanoma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(Tyr-BRAF*V600E)470Fgh/0
involves: 129/Sv * C57BL/6J * CBA * SJL J:151455 View
melanoma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(Tyr-BRAF*V600E)476Fgh/0
involves: 129/Sv * C57BL/6J * CBA * SJL J:151455 View
melanoma Cdkn2atm2Brn/Cdkn2atm2Brn
Tg(Tyr-cre/ERT,-Hras1*,-Trap1a)10BJvde/0
involves: C57BL/6 * FVB/N J:107175 View
skin melanoma Cdkn2atm1Rdp/Cdkn2a+
Tg(Tyr-NRAS*Q61K)1Bee/?
involves: 129/Sv * C57BL/6 * DBA/2 * SJL J:98545 View
skin melanoma Cdkn2atm1Rdp/Cdkn2atm1Rdp
Tg(Tyr-NRAS*Q61K)1Bee/?
involves: 129/Sv * C57BL/6 * DBA/2 * SJL J:98545 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Krastm4Tyj/Kras+
Tg(Tyr-cre/ERT2)13Bos/0
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Cdkn2atm2.1Nesh Krastm4Tyj J:220627 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Nrastm1.1Nesh/Nrastm1.1Nesh
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(Tyr-cre/ERT2)13Bos/0
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh Stk11tm1.1Rdp J:220627 View
skin melanoma Cdkn2atm2.1Nesh/Cdkn2atm2.1Nesh
Nrastm1.1Nesh/Nrastm1.1Nesh
Tg(Tyr-cre/ERT2)13Bos/0
B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nrastm1.1Nesh Cdkn2atm2.1Nesh J:220627 View
Transgenes and
Other Mutations
     melanoma Ednrbtm1Ywa/Ednrb+
Tg(Mt1-RET)304Ina/0
involves: 129S7/SvEvBrd * BALB/c * C57BL/6 J:155735 View
melanoma Immp2lTg(HLA-A/H2-D)2Enge/0
Tg(Mt1-RET)304Ina/0
involves: BALB/c * C57BL/6 * CBA/Ca J:130879 View
melanoma Tg(Mt1-RET)304Ina/0 involves: BALB/c * C57BL/6 J:155735 View
skin melanoma Tg(CAG-Ptafr)1Tksh/0 B6;D2-Tg(CAG-Ptafr)1Tksh/TkshRbrc J:38639 View
skin melanoma Tg(Mt1-RET)304Ina/0 B6.C-Tg(Mt1-RET)304Ina J:50392 View
Additional
Complex
Models
     skin melanoma Braftm1Mmcm/Braf+
Ptentm1Rdp/Ptentm1Rdp
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N J:151023 View
skin melanoma Braftm1Mmcm/Braf+
Ptentm2.1Ppp/Ptentm2.1Ppp
Tg(Tyr-cre/ERT2)13Bos/0
involves: 129P2/OlaHsd * 129S1/Sv * FVB J:151023 View
skin melanoma Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Tg(Mt1-Hgf)#Lmb/0
B6.Cg-Cdk4tm1.1Bbd Tg(Mt1-Hgf)#Lmb J:111992 View
skin melanoma Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Tg(Tyr-NRAS*Q61K)1Bee/0
FVB.Cg-Cdk4tm1.1Bbd Tg(Tyr-NRAS*Q61K)1Bee J:222847 View
skin melanoma Xpatm1Tnka/Xpatm1Tnka
Tg(KRT14-Kitl)1Takk/?
involves: C57BL/6 * CBA * SJL J:100608 View
uveal melanoma Cdkn2atm1Rdp/Cdkn2a+
X/Tg(Tyr-HRAS)60Lc
involves: 129/Sv * C57BL/6J * CBA/J * FVB/N * SJL J:140820 View
uveal melanoma Gt(ROSA)26Sortm1(GNAQ*)Cvrk/Gt(ROSA)26Sor+
Tg(Mitf-cre)7114Gsb/0
C3FeJ.Cg-Gt(ROSA)26Sortm1(GNAQ*)Cvkr Tg(Mitf-cre)7114Gsb/Cvrk J:225597 View