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All mouse models of thyroid cancer with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | thyroid gland papillary carcinoma |
Braftm1Cpri/Braftm1Cpri Tg(TPO-cre)1Shk/0 |
involves: 129P2/OlaHsd * FVB/NCr | J:168249 | View | |||
| thyroid gland papillary carcinoma |
Braftm1Mmcm/Braf+ Tg(Tg-cre/ERT2)#Mmcm/0 |
involves: 129P2/OlaHsd | J:172205 | View | ||||
| | familial medullary thyroid carcinoma | Prlrtm1Cnp/Prlrtm1Cnp | involves: 129/Sv * 129P2/OlaHsd | J:101609 | View | |||
| thyroid gland follicular carcinoma |
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Ptentm1.1Mwst/Ptentm1.1Mwst Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/NCr | J:241066 | View | ||||
| thyroid gland follicular carcinoma |
Prkar1atm1.2Lsk/Prkar1atm1.2Lsk Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129X1/SvJ * FVB/NCr | J:241066 | View | ||||
| thyroid gland follicular carcinoma |
Ptentm1Hwu/Pten+ Tg(Nkx2-1-cre)2Sand/0 |
B6.Cg-Ptentm1Hwu Tg(Nkx2-1-cre)2Sand | J:197590 | View | ||||
| thyroid gland follicular carcinoma |
Ptentm2.1Ppp/Ptentm2.1Ppp Tg(TPO-cre)1Shk/0 |
129S1.Cg-Ptentm2.1Ppp Tg(TPO-cre)1Shk | J:165293 | View | ||||
| thyroid gland follicular carcinoma | Thrbtm1.1Syc/Thrbtm1.1Syc | involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J | J:92629 | View | ||||
| thyroid gland follicular carcinoma | Thrbtm1Df/Thrbtm1.1Syc | involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * C57BL/6J | J:92629 | View | ||||
| Transgenes and Other Mutations | thyroid cancer | Tg(TG-TPR/NTRK1)#Rstn/0 | involves: 129S4/SvJaeSor * C3H * C57BL/6 * C57BL/6J | J:210015 | View | |||
| thyroid gland follicular carcinoma | Tg(TG-NRAS*Q61K)#Msnt/0 | Not Specified | J:210016 | View | ||||
| thyroid gland papillary carcinoma |
Tg(tetO-BRAF*V600E)26Jaf/0 Tg(TG-rtTA)30Jaf/0 |
involves: FVB/N | J:184420 | View | ||||
| thyroid gland papillary carcinoma | Tg(TG-BRAF*V600E)2Jaf/0 | FVB/N-Tg(TG-BRAF*V600E)2Jaf | J:98550, J:195921 | View | ||||
| thyroid gland papillary carcinoma | Tg(TG-RET/CCDC6)42Cled/0 | involves: FVB/N | J:93679, J:55883 | View | ||||
| thyroid gland papillary carcinoma | Tg(TG-RET/NCOA4)3209Rstn/0 | involves: C57BL/6 | J:51366 | View | ||||
| thyroid gland papillary carcinoma | Tg(TG-TPR/NTRK1)5215Rstn/0 | involves: C3H * C57BL/6 | J:67120 | View | ||||
| Additional Complex Models | thyroid cancer |
Hrastm1Jaf/Hrastm1Jaf Nf2tm2Gth/Nf2tm2Gth Tg(TPO-cre)1Shk/0 |
involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * FVB/NCr | J:231492 | View | |||
| thyroid cancer |
Hrastm1Jaf/Hrastm1Jaf Ptentm2.1Ppp/Ptentm2.1Ppp Tg(TPO-cre)1Shk/0 |
involves: 129S1/Sv * 129S6/SvEvTac * FVB/NCr | J:231492 | View | ||||
| thyroid cancer |
Hrastm1Jaf/Hrastm1Jaf Trp53tm1Brn/Trp53tm1Brn Tg(TPO-cre)1Shk/0 |
involves: 129P2/OlaHsd * 129S6/SvEvTac * Black Swiss * C57BL/6 * FVB/NCr | J:231492 | View | ||||
| thyroid gland carcinoma |
Ptentm1Hwu/Ptentm1Hwu Tg(CAG-EGFP,-PAX8/PPARG)1Rkoe/0 Tg(TPO-cre)1Shk/0 |
involves: 129S4/SvJae * FVB/NCr * FVB/NJ | J:177181 | View | ||||
| thyroid gland carcinoma |
Ptentm2.1Ppp/Ptentm2.1Ppp Trp53tm1Brn/Trp53tm1Brn Tg(TPO-cre)1Shk/0 |
129.Cg-Tg(TPO-cre)1Shk Trp53tm1Brn Ptentm2.1Ppp | J:211100 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | familial medullary thyroid carcinoma | Rettm2.1Cos/Ret+ | involves: 129S1/Sv * C57BL/6J * FVB/N | J:60659 | View | |||
| familial medullary thyroid carcinoma | Rettm2.1Cos/Rettm2.1Cos | involves: 129S1/Sv * C57BL/6J * FVB/N | J:60659 | View | ||||