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Tg(TG-NRAS*Q61K)#Msnt
Transgene Detail
Summary
Symbol: Tg(TG-NRAS*Q61K)#Msnt
Name: transgene insertion, Massimo Santoro
MGI ID: MGI:5570240
Synonyms: N-ras(Gln61Lys), Tg-N-ras
Transgene: Tg(TG-NRAS*Q61K)#Msnt  Location: unknown  
Alliance: Tg(TG-NRAS*Q61K)#Msnt page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(TG-NRAS*Q61K)#Msnt expresses 1 gene
 
Mutation detailsThis transgene contained the bovine thyroglobulin (TG) promoter and expressed human NRAS carrying a Q61K (Gln61Lys) point mutation. No data was given on the number of founders or number of transgenic lines established. (# - line not specified) (J:210016)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:210016 Vitagliano D, et al., Thyroid targeting of the N-ras(Gln61Lys) oncogene in transgenic mice results in follicular tumors that progress to poorly differentiated carcinomas. Oncogene. 2006 Aug 31;25(39):5467-74
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory