All Phenotypes T<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

T⁺
wild type
MGI:1857758

Summary

80 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	T^8J/T⁺	C57BL/6J-Apoe^tm1Unc	MGI:3575023
ht2	T^11J/T⁺	C57BL/6J-T^11J/GrsrJ	MGI:5436052
ht3	T^2J/T⁺	C57BL/6J-T^2J/J	MGI:4442983
ht4	T^5J/T⁺	C57BL/6J-T^5J/J	MGI:4830532
ht5	T^7J/T⁺	C57BL/6J-T^7J	MGI:3702744
ht6	T^9J/T⁺	C57BL/6J-T^9J	MGI:3575024
ht7	T^{Tg(MT2A-Myc)137Misu}/T⁺	C57BL/6-T^{Tg(MT2A-Myc)137Misu}	MGI:3710088
ht8	T^24H/T⁺	involves: 101/H * C3H/HeH	MGI:5471530
ht9	T^c-2H/T⁺	involves: 101/H * C3H/HeH	MGI:4461910
ht10	T^26H/T⁺	involves: 101/H * C3H/HeH	MGI:5450870
ht11	T^31H/T⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719843
ht12	T^33H/T⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719845
ht13	T^36H/T⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719849
ht14	T^41H/T⁺	involves: 101/Rl * BALB/cOlaHsd * C3H/Rl	MGI:3056913
ht15	T^Wis/T⁺	involves: A/J	MGI:3844471
ht16	T^6J/T⁺	involves: A/J * C57BL/6J	MGI:5299330
ht17	T^4J/T⁺	involves: BALB/cBy	MGI:4830250
ht18	T^39H/T⁺	involves: BALB/c * C3H/HeN	MGI:2174751
ht19	T^c-3H/T⁺	involves: BALB/cOlaHsd * C3H/HeH	MGI:3056915
ht20	T^29H/T⁺	involves: BALB/c * TFH	MGI:3719851
ht21	T^40H/T⁺	involves: C3H/HeH * C57BL/6J	MGI:3056911
ht22	T^M1Shao/T⁺	involves: C57BL/6J	MGI:4867538
ht23	T^{tm1(cre/ERT2)Hssk}/T⁺	involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR	MGI:5490042
ht24	T^34H/T⁺	involves: STOCK T^34H * TFH	MGI:3719850
ht25	T^c/T⁺	mixed	MGI:3619235
ht26	T/T⁺	Not Specified	MGI:3663264
ht27	T^Wis/T⁺	Not Specified	MGI:2169528
ht28	T^c/T⁺	Not Specified	MGI:3783758
ht29	T^h/T⁺	Not Specified	MGI:4360106
ht30	T^Jic/T⁺	Not Specified	MGI:4360190
cx31	T^24H/T⁺ t^h2/t⁺	involves: 101/H * C3H/HeH	MGI:5471531
cx32	T^34H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * STOCK T^34H * TFH	MGI:3719857
cx33	T^32H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719856
cx34	T^36H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719862
cx35	T^33H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719847
cx36	T^30H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719859
cx37	T^32H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719860
cx38	T^22H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719863
cx39	T^32H/T⁺ t^h51/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719853
cx40	T^30H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719846
cx41	Nox3^het/Nox3^het T^36H/T⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719848
cx42	Nox3^het/Nox3^het T^31H/T⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719841
cx43	Nox3^het/Nox3^het T^33H/T⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719844
cx44	T^36H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719852
cx45	T^31H/T⁺ t^w32/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719842
cx46	Sp5^tm1Rbe/Sp5^tm1Rbe T/T⁺	involves: 129P2/Ola * C57BL/6J	MGI:3029242
cx47	T^4J/t⁶	involves: BALB/cBy	MGI:4830251
cx48	T^29H/T⁺ t⁶/t⁺	involves: BALB/c * TFH	MGI:3719858
cx49	T^29H/T⁺ t^w32/t⁺	involves: BALB/c * TFH	MGI:3719854
cx50	Itpr3^tf/Itpr3⁺ T/T⁺ t^hr4/t⁺	involves: BTBR	MGI:5465159
cx51	T/T⁺ t^h7m2/t⁺ Itpr3^tf/Itpr3⁺	involves: BTBR	MGI:5465016
cx52	T/t^wPas1	involves: BTBR/Nev T * M. m. brevirostris	MGI:4821115
cx53	T^c/T⁺ Tg(T)118.9Bgh/Tg(T)118.9Bgh	involves: C57BL/6 * CBA	MGI:3784943
cx54	T/T⁺ Tg(T)118.9Bgh/0	involves: C57BL/6 * CBA	MGI:3784873
cx55	T^c/T⁺ Tg(T)118.9Bgh/0	involves: C57BL/6 * CBA	MGI:3784872
cx56	T^c/t^h51 Tg(T)118.9Bgh/0	involves: C57BL/6 * CBA	MGI:3784944
cx57	T^5J/t⁶	involves: C57BL/6J	MGI:4830536
cx58	T/t^btm	involves: C57BL/6 * MOL-NIS	MGI:4457262
cx59	T/t^wPas2	involves: M. m. brevirostris	MGI:4821153
cx60	T/t^wPas3	involves: M. m. domesticus	MGI:4821268
cx61	T/t^w73	involves: M. m. musculus	MGI:5288480
cx62	T/t^btm	MOL-NIS	MGI:4819839
cx63	T t⁺/T⁺ t^h17	Not Specified	MGI:4844309
cx64	T t^s6/T⁺ t⁺	Not Specified	MGI:4839335
cx65	T/T⁺ t^h7m/t⁺	Not Specified	MGI:5465011
cx66	T/T⁺ t^h7m2/t⁺	Not Specified	MGI:5465018
cx67	T/T⁺ t^hr1/t⁺	Not Specified	MGI:5465026
cx68	T/T⁺ t^hr15/t⁺	Not Specified	MGI:5465028
cx69	T/T⁺ t^hr4/t⁺	Not Specified	MGI:5465155
cx70	T/T⁺ t^low2H/t⁺	Not Specified	MGI:5465165
cx71	T/t^AE5	Not Specified	MGI:4461426
cx72	T/t⁴	Not Specified	MGI:4461305
cx73	T/t^wN27	Not Specified	MGI:4460903
cx74	T/t^w3	Not Specified	MGI:5906043
cx75	T/t^ks1	Not Specified	MGI:4458399
cx76	T^h/t¹³	Not Specified	MGI:4360117
cx77	T/t⁶	Not Specified	MGI:3663265
cx78	T t⁺/T⁺ t^Tu3	Not Specified	MGI:5284985
cx79	T t^h20/T⁺ t⁺	Not Specified	MGI:4868366
cx80	T t⁺/T⁺ t^h45	Not Specified	MGI:4868204

Allelic Composition	T^8J/T⁺
Genetic Background	C57BL/6J-Apoe^tm1Unc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^8J mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:72464 )

• length varies from nearly normal to absent

Allelic Composition	T^11J/T⁺
Genetic Background	C57BL/6J-T^11J/GrsrJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^11J mutation (1 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Short and kinked tail in the T^11J/T⁺ mouse

limbs/digits/tail

abnormal tail development ( J:187215 )

• the tail can be high set

short tail ( J:187215 )

• tail length varies from one heterozygote to the next with some having nearly normal tail length and others having almost no tail

kinked tail ( J:187215 )

• the tail is often blunt or kinked

skeleton

abnormal pelvic girdle bone morphology ( J:187215 )

• some heterozygotes have been found to have reduced pelvic size with hip bones closer together than normal

digestive/alimentary system

absent anus ( J:187215 )

• some heterozygotes have been found to have no anal opening

Allelic Composition	T^2J/T⁺
Genetic Background	C57BL/6J-T^2J/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^2J mutation (2 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:78474 )

Allelic Composition	T^5J/T⁺
Genetic Background	C57BL/6J-T^5J/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^5J mutation (1 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:78379 )

Allelic Composition	T^7J/T⁺
Genetic Background	C57BL/6J-T^7J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^7J mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:44446 )

Allelic Composition	T^9J/T⁺
Genetic Background	C57BL/6J-T^9J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^9J mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:72463 )

• length varies from nearly normal to absent

Allelic Composition	T^{Tg(MT2A-Myc)137Misu}/T⁺
Genetic Background	C57BL/6-T^{Tg(MT2A-Myc)137Misu}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^{Tg(MT2A-Myc)137Misu} mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

kinked tail ( J:60706 )

• most mutants have a kinked or bent tail

Allelic Composition	T^24H/T⁺
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^24H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:169366 )

Allelic Composition	T^c-2H/T⁺
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^c-2H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:85396 )

• preweaning mortality is 14% compared with 3% seen in matings of wild-type mice

limbs/digits/tail

abnormal tail morphology ( J:85396 )

absent tail ( J:85396 )

• tailless mice of this genotype are not uncommon

vestigial tail ( J:85396 )

• typically possessing only a short bone-less caudal filament

Allelic Composition	T^26H/T⁺
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^26H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:169366 )

Allelic Composition	T^31H/T⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^31H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:62655 )

• fewer than expected mice are born

reproductive system

reduced male fertility ( J:62655 )

• some males are infertile

Allelic Composition	T^33H/T⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^33H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:62655 )

• fewer than expected mice are born

reproductive system

reduced male fertility ( J:62655 )

• some males are infertile

Allelic Composition	T^36H/T⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^36H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:62655 )

• fewer than expected mice are born

reproductive system

reduced male fertility ( J:62655 )

• some males are infertile

limbs/digits/tail

short tail ( J:62655 )

• fewer than expected (27.1%) of mice are short-tailed

Allelic Composition	T^41H/T⁺
Genetic Background	involves: 101/Rl * BALB/cOlaHsd * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^41H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:93195 )

Allelic Composition	T^Wis/T⁺
Genetic Background	involves: A/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^Wis mutation (1 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:9032 )

Allelic Composition	T^6J/T⁺
Genetic Background	involves: A/J * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^6J mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:78380 )

Allelic Composition	T^4J/T⁺
Genetic Background	involves: BALB/cBy

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^4J mutation (1 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:30778 )

Allelic Composition	T^39H/T⁺
Genetic Background	involves: BALB/c * C3H/HeN

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^39H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:63816 )

Allelic Composition	T^c-3H/T⁺
Genetic Background	involves: BALB/cOlaHsd * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^c-3H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:93195 )

Allelic Composition	T^29H/T⁺
Genetic Background	involves: BALB/c * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^29H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:62655 )

• fewer than expected mice are born

Allelic Composition	T^40H/T⁺
Genetic Background	involves: C3H/HeH * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^40H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:93195 )

Allelic Composition	T^M1Shao/T⁺
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^M1Shao mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:166619 )

• ranging from 1 cm to half of normal tail length

curly tail ( J:166619 )

Allelic Composition	T^{tm1(cre/ERT2)Hssk}/T⁺
Genetic Background	involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^{tm1(cre/ERT2)Hssk} mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:194054 )

• mice show varying degrees of tail defects similar heterozygous brachyury (T) mutants

short tail ( J:194054 )

• observed in some heterozygotes

absent tail ( J:194054 )

• observed in some heterozygotes

curly tail ( J:194054 )

• observed in some heterozygotes

Allelic Composition	T^34H/T⁺
Genetic Background	involves: STOCK T^34H * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^34H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:62655 )

• few heterozygotes mice of heterozygote females survive birth

homeostasis/metabolism

edema ( J:62655 )

limbs/digits/tail

short tail ( J:62655 )

Allelic Composition	T^c/T⁺
Genetic Background	mixed

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^c mutation (3 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail bud morphology ( J:106412 )

• by E 12, mutants show constriction at the base of the tail

• later in development, the abnormalities observed are less severe and occur more posteriorly than in T^c/t^w5 embryos

nervous system

abnormal neural tube morphology ( J:106412 )

• at E12.5, one accessory neural tube is observed

spina bifida occulta ( J:106412 )

• unlike T/t<25> mutants, the dermis over the bony defect of the spinal cord does not become attenuated and rupture

abnormal spinal cord morphology ( J:106412 )

• embryos display ventral duplication of the spinal cord

embryo

abnormal neural tube morphology ( J:106412 )

• at E12.5, one accessory neural tube is observed

spina bifida occulta ( J:106412 )

• unlike T/t<25> mutants, the dermis over the bony defect of the spinal cord does not become attenuated and rupture

split notochord ( J:106412 )

• some embryos show duplication or intermittent absence of the notochord

abnormal tail bud morphology ( J:106412 )

• by E 12, mutants show constriction at the base of the tail

• later in development, the abnormalities observed are less severe and occur more posteriorly than in T^c/t^w5 embryos

skeleton

spina bifida occulta ( J:106412 )

• unlike T/t<25> mutants, the dermis over the bony defect of the spinal cord does not become attenuated and rupture

absent vertebrae ( J:106412 )

• embryos display partial or complete absence of bony vertebrae posterior to midliver level

Allelic Composition	T/T⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

decreased ventral ectodermal ridge size ( J:15081 )

• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 74% of normal size

decreased caudal vertebrae number ( J:15081 )

• caudal vertebrae numbers range from 10 to 24, with an average of 21

short tail ( J:13018 , J:15081 )

• seen by E11 (J:13018)

• tail is reduced by about 1/3 in most mutants (J:15081)

embryo

abnormal neural tube morphology ( J:13018 )

• neural tube is abnormal/misshapen in the ventral part and in cases in which the notochord is abnormal

abnormal notochord morphology ( J:13018 , J:15081 )

• contain a notochord, however it can be retained in the roof of the gut or cloaca for varying distances and for a limited period, it may be slow to separate from the overlying neural plate or neural tube, or it may secondarily become incorporated completely into the neural tube or the tail-gut (J:15081)

• the notocord has a central lumen in places (J:15081)

• commonly see branching of the notochord proper; at E10-12.5, branches occur mainly in the region of the cloaca and the proximal parts of the tail (J:15081)

decreased ventral ectodermal ridge size ( J:15081 )

• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 74% of normal size

skeleton

decreased caudal vertebrae number ( J:15081 )

• caudal vertebrae numbers range from 10 to 24, with an average of 21

decreased presacral vertebrae number ( J:15081 )

nervous system

abnormal neural tube morphology ( J:13018 )

• neural tube is abnormal/misshapen in the ventral part and in cases in which the notochord is abnormal

Allelic Composition	T^Wis/T⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^Wis mutation (1 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal rostral-caudal axis patterning ( J:16412 )

• axial development is disrupted at a more anterior position that in other alleles of this locus

abnormal neural tube morphology ( J:16412 )

incomplete caudal neuropore closure ( J:16412 )

absent notochord ( J:16412 )

abnormal tail bud morphology ( J:16412 )

skeleton

decreased rib number ( J:16412 )

abnormal sacral vertebrae morphology ( J:16412 )

fusion of vertebral arches ( J:16412 )

abnormal vertebral body morphology ( J:16412 )

absent vertebral body ( J:16412 )

nervous system

abnormal neural tube morphology ( J:16412 )

incomplete caudal neuropore closure ( J:16412 )

limbs/digits/tail

abnormal tail bud morphology ( J:16412 )

short tail ( J:16412 )

• extremely short tail; more severe than other alleles at this locus

thin tail ( J:16412 )

Allelic Composition	T^c/T⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^c mutation (3 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:5003 )

• ratio of mutant to wild-type is less than 1 to 1 at birth

postnatal lethality ( J:5003 )

• 32% of curtailed mice die between birth and weaning

limbs/digits/tail

abnormal tail morphology ( J:5003 , J:64262 )

• while approximately 5% of heterozygotes have a short tail not more than 20% normal length, most have no normal tail but a short boneless caudal filament (J:5003)

• tail is reduced to a very short curly filament without skeleton and in some instances the tail is altogether absent (J:64262)

short tail ( J:5003 , J:64262 )

absent tail ( J:5003 , J:64262 )

skeleton

rib fusion ( J:5003 )

• often extensive in the thoracic region

short ribs ( J:5003 )

abnormal nucleus pulposus morphology ( J:5003 )

• aside from slight traces in the lower thoracic and lumbar regions, the intervertebral nuclei pulposi are absent at 3 weeks of age

abnormal cervical vertebrae morphology ( J:5003 )

abnormal cervical atlas morphology ( J:5003 )

• the neural arch is partially double in some heterozygotes

abnormal odontoid process morphology ( J:5003 )

• the axis odontoid process is absent resulting in a horseshoe-shaped articulation between the atlas and axis

decreased presacral vertebrae number ( J:5003 )

abnormal vertebral arch development ( J:5003 )

vertebral fusion ( J:5003 )

thoracic vertebral fusion ( J:5003 )

cervical vertebral fusion ( J:5003 )

• between the second and third vertebrae

fusion of vertebral arches ( J:5003 )

abnormal bone ossification ( J:5003 )

• the centra of cervical vertebrae are wider than normal, the axis tends to ossify from twin centers, and distortion and fusion is found in some throacic centra

Allelic Composition	T^h/T⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^h mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:13072 )

• the tail of the original mouse was half normal length

Allelic Composition	T^Jic/T⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^Jic mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:14257 )

Allelic Composition	T^24H/T⁺ t^h2/t⁺
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^24H mutation (0 available); any T mutation (60 available)
t^h2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:169366 )

Allelic Composition	T^34H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * STOCK T^34H * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^34H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• fewer than expected carried the T^34H allele

Allelic Composition	T^32H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^32H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• fewer than expected carried the T^32H allele

Allelic Composition	T^36H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^36H mutation (0 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^33H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^33H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• fewer than expected carried the T^33H allele

reduced male fertility ( J:62655 )

• male fertility is low

Allelic Composition	T^30H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^30H mutation (0 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^32H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^32H mutation (0 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^22H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^22H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male infertility ( J:62655 )

Allelic Composition	T^32H/T⁺ t^h51/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^32H mutation (0 available); any T mutation (60 available)
t^h51 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• fewer than expected offsprings carried the t^h51 allele

Allelic Composition	T^30H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^30H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male infertility ( J:62655 )

Allelic Composition	Nox3^het/Nox3^het T^36H/T⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nox3^het mutation (2 available); any Nox3 mutation (38 available)
T^36H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

head tilt ( J:62655 )

Allelic Composition	Nox3^het/Nox3^het T^31H/T⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nox3^het mutation (2 available); any Nox3 mutation (38 available)
T^31H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

head tilt ( J:62655 )

Allelic Composition	Nox3^het/Nox3^het T^33H/T⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nox3^het mutation (2 available); any Nox3 mutation (38 available)
T^33H mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

head tilt ( J:62655 )

Allelic Composition	T^36H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^36H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:62655 )

• viability is poor and no males survive into adulthood

Allelic Composition	T^31H/T⁺ t^w32/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^31H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

male infertility ( J:62655 )

Allelic Composition	Sp5^tm1Rbe/Sp5^tm1Rbe T/T⁺
Genetic Background	involves: 129P2/Ola * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sp5^tm1Rbe mutation (0 available); any Sp5 mutation (15 available)
T mutation (23 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

decreased caudal vertebrae number ( J:65743 )

• majority of tails are comprised of fewer than 8 vertebrae

short tail ( J:65743 )

skeleton

abnormal vertebrae morphology ( J:65743 )

decreased caudal vertebrae number ( J:65743 )

• majority of tails are comprised of fewer than 8 vertebrae

abnormal lumbar vertebrae morphology ( J:65743 )

• lumbar vertebrae defect consisting of an imperfect fusion of the two ventral halves of the vertebra, resulting in an abnormal centrum

Allelic Composition	T^4J/t⁶
Genetic Background	involves: BALB/cBy

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^4J mutation (1 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:30778 )

Allelic Composition	T^29H/T⁺ t⁶/t⁺
Genetic Background	involves: BALB/c * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^29H mutation (0 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^29H/T⁺ t^w32/t⁺
Genetic Background	involves: BALB/c * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^29H mutation (0 available); any T mutation (60 available)
t^w32 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• no offsprings carried the T^29H allele

Allelic Composition	Itpr3^tf/Itpr3⁺ T/T⁺ t^hr4/t⁺
Genetic Background	involves: BTBR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3^tf mutation (20 available); any Itpr3 mutation (174 available)
T mutation (23 available); any T mutation (60 available)
t^hr4 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:169366 )

• high transmission ratio distortion in favour of the t^hr4 haplotype from males

Allelic Composition	T/T⁺ t^h7m2/t⁺ Itpr3^tf/Itpr3⁺
Genetic Background	involves: BTBR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3^tf mutation (20 available); any Itpr3 mutation (174 available)
T mutation (23 available); any T mutation (60 available)
t^h7m2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:34190 )

N	• mice exhibit normal fertility

Allelic Composition	T/t^wPas1
Genetic Background	involves: BTBR/Nev T * M. m. brevirostris

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^wPas1 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:6461 )

• when males of this genotype are mated to wild-type females the t-haplotype appears among teh offspring more frequently than expected

reproductive system

transmission ratio distortion ( J:6461 )

Allelic Composition	T^c/T⁺ Tg(T)118.9Bgh/Tg(T)118.9Bgh
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^c mutation (3 available); any T mutation (60 available)
Tg(T)118.9Bgh mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:3956 )

• most curtailed heterozygotes homozygous for this transgene have normal length tails with blunted ends, but a minority have short tails

Allelic Composition	T/T⁺ Tg(T)118.9Bgh/0
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
Tg(T)118.9Bgh mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:3956 )

N	• in the presence of T, transgene carriers have normal length tails, indicative of a complete rescue of phenotype

Allelic Composition	T^c/T⁺ Tg(T)118.9Bgh/0
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^c mutation (3 available); any T mutation (60 available)
Tg(T)118.9Bgh mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:3956 )

• most transgene carriers have a short tail, a partial rescue of the curtailed phenotype, and the tail length varies from one-eighth to three-fourths normal tail length

Allelic Composition	T^c/t^h51 Tg(T)118.9Bgh/0
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^c mutation (3 available); any T mutation (60 available)
Tg(T)118.9Bgh mutation (0 available)
t^h51 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:3956 )

• six of seven found to have short tails with the seventh having no tail; this is a partial rescue of the compound heterozygous phenotype in the absence of the transgene wherein sevin out of sevin have a tailless phenotype

Allelic Composition	T^5J/t⁶
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^5J mutation (1 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:78379 )

Allelic Composition	T/t^btm
Genetic Background	involves: C57BL/6 * MOL-NIS

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^btm mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal rostral-caudal body axis extension ( J:21054 )

• attenuated development of the posterior part of the body

abnormal neural tube morphology ( J:21054 )

• generally distorted, duplicated or fused with the mesenchyme

meningomyelocele ( J:21054 )

• presents as a dorsal blood blister in the lumbosacral region

abnormal notochord morphology ( J:21054 )

• E11-12 embryos show abnormalities in the medio-dorsal area

notochord degeneration ( J:21054 )

• seen in E11-12 embryos

split notochord ( J:21054 )

• seen in E11-12 embryos

abnormal tail bud morphology ( J:21054 )

• at E10 a constriction occurs as the tail develops

nervous system

abnormal neural tube morphology ( J:21054 )

• generally distorted, duplicated or fused with the mesenchyme

meningomyelocele ( J:21054 )

• presents as a dorsal blood blister in the lumbosacral region

abnormal spinal cord morphology ( J:21054 )

• posterior to the lumbosacral level the cord is severely distorted or duplicated and devoid of vertebrae

limbs/digits/tail

absent caudal vertebrae ( J:21054 )

abnormal tail development ( J:21054 )

abnormal tail bud morphology ( J:21054 )

• at E10 a constriction occurs as the tail develops

absent tail ( J:21054 )

• mice with this genotype lack a tail at birth and have blood listers or red scars on the dorsal skin at the middle of the lumbosacral region

skeleton

meningomyelocele ( J:21054 )

• presents as a dorsal blood blister in the lumbosacral region

absent caudal vertebrae ( J:21054 )

abnormal thoracic vertebrae morphology ( J:21054 )

• rib fusions, lack of vertebral bodies and arches

abnormal lumbar vertebrae morphology ( J:21054 )

• rib fusions, lack of vertebral bodies and arches

absent sacral vertebrae ( J:21054 )

absent vertebral arch ( J:21054 )

• an abnormality of thoracic and lumbar vertebrae

absent vertebral body ( J:21054 )

• an abnormality of thoracic and lumbar vertebrae

absent vertebrae ( J:21054 )

Allelic Composition	T/t^wPas2
Genetic Background	involves: M. m. brevirostris

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^wPas2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:6461 )

reproductive system

transmission ratio distortion ( J:6461 )

• in a test cross with a wild-type female mouse the t-haplotype is seen in offspring less frequently than expected

Allelic Composition	T/t^wPas3
Genetic Background	involves: M. m. domesticus

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^wPas3 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:6461 )

reproductive system

transmission ratio distortion ( J:6461 )

• when males of this genotype are mated to wild-type females the t haplotype occurs among the offspring more frequently than expected

Allelic Composition	T/t^w73
Genetic Background	involves: M. m. musculus

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^w73 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:175677 )

• males of this genotype transmit t^w73 to 88.6 per cent of offspring

limbs/digits/tail

absent tail ( J:175677 )

• all mice of this genotype are tailless

Allelic Composition	T/t^btm
Genetic Background	MOL-NIS

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^btm mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased survivor rate ( J:14919 )

• all mice are dead by 60 days of age; the few longest-lived have hind-limb paralysis

perinatal lethality, incomplete penetrance ( J:14919 )

• most die shortly after birth and have a blood blister in the lumbosacral area and hind-limb paralysis

limbs/digits/tail

absent tail ( J:14919 )

• all mice of this genotype are tailless

reproductive system

reproductive system phenotype ( J:14919 )

N	• mice are fertile and there is no evidence of transmission ratio distortion

Allelic Composition	T t⁺/T⁺ t^h17
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h17 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:5889 )

• mice with this genotype have short tails; they are not tailless as are mice heterozygous for brachyury and carrying any of the majority of other t haplotypes

• there is no transmission ratio distortion as might be expected from males of this genotype

Allelic Composition	T t^s6/T⁺ t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^s6 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:6478 )

• 85% of offspring produced from 3 matings of Tt^s6 males to wild-type females are short-tailed; 15% are normal-tailed

Allelic Composition	T/T⁺ t^h7m/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h7m mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:34190 )

Allelic Composition	T/T⁺ t^h7m2/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h7m2 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:34190 )

Allelic Composition	T/T⁺ t^hr1/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^hr1 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:183153 )

Allelic Composition	T/T⁺ t^hr15/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^hr15 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:192386 )

Allelic Composition	T/T⁺ t^hr4/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^hr4 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:169366 )

Allelic Composition	T/T⁺ t^low2H/t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^low2H mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:183153 )

N	• no effect on tail length

Allelic Composition	T/t^AE5
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^AE5 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:83862 )

absent tail ( J:83862 )

Allelic Composition	T/t⁴
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t⁴ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:36683 )

absent tail ( J:36683 )

reproductive system

transmission ratio distortion ( J:36683 )

• T-bearing gametes are in excess although not uniformly the case from male to male

Allelic Composition	T/t^wN27
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^wN27 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:32745 )

• indicative of the presence of a t haplotype

Allelic Composition	T/t^w3
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^w3 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:23652 )

Allelic Composition	T/t^ks1
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^ks1 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:8922 )

reproductive system

transmission ratio distortion ( J:8922 )

• only 37% of sperm from males of this genotype carry the t^ks1 haplotype

Allelic Composition	T^h/t¹³
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t¹³ mutation (0 available); any t mutation (19 available)
T^h mutation (0 available); any T mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:13072 )

Allelic Composition	T/t⁶
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

decreased ventral ectodermal ridge size ( J:15081 )

• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size

embryo

abnormal notochord morphology ( J:15081 )

• the notochord is increased in bulk not only in the distal growth zone (as in T heterozygotes) but in the whole tail, in the cloacal region and even more anteriorly in the lumbar region and has large lumina

• the notochord is present throughout the length of the tail, however it becomes incorporated into the neural tube throughout the tail and often the cloacal region

decreased ventral ectodermal ridge size ( J:15081 )

• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size

Allelic Composition	T t⁺/T⁺ t^Tu3
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^Tu3 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:6700 )

N	• the tail length is normal although a mouse inheriting a t haplotype with T is frequently tailless

Allelic Composition	T t^h20/T⁺ t⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h20 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:5889 )

Allelic Composition	T t⁺/T⁺ t^h45
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t^h45 mutation (1 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:7443 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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