T^c-2H
Chemically and radiation induced Allele Detail

Summary

• Symbol: T^c-2H
• Name: brachyury, T-box transcription factor T; curtailed 2 Harwell
• MGI ID: MGI:1856193
• Gene: T Location: Chr17:8653255-8661328 bp, + strand Genetic Position: Chr17, 4.92 cM
• Alliance: T^c-2H page

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Chemically and radiation induced
• Mutation: Single point mutation
• Mutation details: Sequencing genomic DNA from the open reading frame revealed a C to A transversion that would result in a protein truncated at the carboxyl-terminal end. (J:85398)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any T Mutation: 60 strains or lines available

References

• Original: J:85396 Cattanach BM, et al., A new curtailed mutation. Mouse News Lett. 1987;77:122
• All: 3 reference(s)