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Gene Expression Data
Assay Details
Assay
Reference: J:290119 Soleilhavoup C, et al., Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. Nat Commun. 2020 Jun 19;11(1):3111
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8270488
Gene symbol: Zfp503
Gene name: zinc finger protein 503
Antibody: Anti-Zfp503 (HPA026848)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: Nolz1-/- mutant embryos, in which the coding region of Nolz1 has been replaced by beta-Galactosidase (also referred to as Nolz1<bgal/bgal>). Zfp503<tm1.1Bpb> (neo cassette removed) has been used in the annotations, but it could be Zfp503<tm1Bpb> (neo cassette still present).
Results
Specimen 1e: embryonic day 18.5 (more )
Note: Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: hypothalamus Present 1e
Specimen 1f: embryonic day 18.5; Zfp503tm1.1Bpb/Zfp503tm1.1Bpb (more )
Note: Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: hypothalamus Absent 1f
Specimen 1g: embryonic day 18.5 (more )
Note: Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: corpus striatum Present 1g
Specimen 1h: embryonic day 18.5; Zfp503tm1.1Bpb/Zfp503tm1.1Bpb (more )
Note: Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: corpus striatum Absent 1h
Specimen 1i: embryonic day 18.5 (more )
Note: Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: corpus striatum Present 1i
Specimen 1j: embryonic day 18.5; Zfp503tm1.1Bpb/Zfp503tm1.1Bpb (more )
Note: Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: corpus striatum Absent 1j
Specimen 5b: embryonic day 18.5 (more )
Note: Controls were either: Cre+, Cre+;Nolz1fl/+, or Nolz1fl/fl. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: corpus striatum Present 5b
Specimen 5c: embryonic day 18.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: corpus striatum Weak 5c
Specimen 5d: embryonic day 18.5; Foxd1tm1(GFP/cre)Amc/Foxd1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: corpus striatum Present 5d
Specimen 5e: embryonic day 18.5; En1tm2(cre)Wrst/En1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: corpus striatum Present 5e
Specimen 5b': embryonic day 18.5 (more )
Note: Controls were either: Cre+, Cre+;Nolz1fl/+, or Nolz1fl/fl. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: hypothalamus Present 5b'
Specimen 5c': embryonic day 18.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: hypothalamus Present 5c'
Specimen 5d': embryonic day 18.5; Foxd1tm1(GFP/cre)Amc/Foxd1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: hypothalamus Absent 5d'
Specimen 5e': embryonic day 18.5; En1tm2(cre)Wrst/En1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: hypothalamus Present 5e'
Specimen 5b'': embryonic day 18.5 (more )
Note: Controls were either: Cre+, Cre+;Nolz1fl/+, or Nolz1fl/fl. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: midbrain Present 5b''
Specimen 5c'': embryonic day 18.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: midbrain Present 5c''
Specimen 5d'': embryonic day 18.5; Foxd1tm1(GFP/cre)Amc/Foxd1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: midbrain Present 5d''
Specimen 5e'': embryonic day 18.5; En1tm2(cre)Wrst/En1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: midbrain Absent 5e''
Specimen S5a Foxg1IresCre;Nolz1fl/+: embryonic day 11.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Zfp503tm1.1Pnmn/Zfp503+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: corpus striatum Present S5a
Specimen S5a' Foxg1IresCre;Nolz1fl/fl: embryonic day 11.5; Foxg1tm1.1(cre)Ddmo/Foxg1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: corpus striatum Absent S5a' Expression was selectively ablated from the corpus striatum using Foxg1Cre.
Specimen S5b Foxd1Cre;Nolz1fl/+: embryonic day 11.5; Foxd1tm1(GFP/cre)Amc/Foxd1+, Zfp503tm1.1Pnmn/Zfp503+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hypothalamus Present S5b
Specimen S5b' Foxd1Cre;Nolz1fl/fl: embryonic day 11.5; Foxd1tm1(GFP/cre)Amc/Foxd1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hypothalamus Absent S5b' Expression was selectively ablated from the hypothalamus using Foxd1Cre.
Specimen S5c En1Cre;Nolz1fl/+: embryonic day 11.5; En1tm2(cre)Wrst/En1+, Zfp503tm1.1Pnmn/Zfp503+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: midbrain Present S5c
Specimen S5c' En1Cre;Nolz1fl/fl: embryonic day 11.5; En1tm2(cre)Wrst/En1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: midbrain Absent S5c' Expression was selectively ablated from the midbrain using En1Cre.
Specimen S5h WT: embryonic day 18.5 (more )
Note: Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: midbrain Present S5h WT
Specimen S5h En1Cre;Nolz1fl/fl: embryonic day 18.5; En1tm2(cre)Wrst/En1+, Zfp503tm1.1Pnmn/Zfp503tm1.1Pnmn (more )
Note: Conditional mutant. Double labeled: red - Zfp503; green - Slc6a3 (assay MGI:8270447).
Structure Level Pattern Image Note
TS26: midbrain Absent S5h En1Cre;Nolz1fl/fl
Specimen S7c WT: embryonic day 14.5 (more )
Note: Double labeled: red - Zfp503; green - Nefm (assay MGI:8273417).
Structure Level Pattern Image Note
TS22: corpus striatum Present S7c WT
Specimen S7c Pcdh10-/-: embryonic day 14.5; Pcdh10tm1Lex/Pcdh10tm1Lex (more )
Note: Double labeled: red - Zfp503; green - Nefm (assay MGI:8273417).
Structure Level Pattern Image Note
TS22: corpus striatum Present S7c Pcdh10-/-
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory