Gene Expression Image Detail

Reference

Figure

ID

J:290119 Soleilhavoup C, et al., Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. Nat Commun. 2020 Jun 19;11(1):3111

5

MGI:8268993

Image

Caption

a Schematic representation of conditional Nolz1 locus and Cre deleter lines used to ablate Nolz1 in the following regions: En1Cre for midbrain, FoxD1Cre for hypothalamic and FoxG1-IRES-Cre line for telencephalic selective recombination. b-e Immunostaining on coronal sections at E18.5 in: Control, FoxG1-IRES-Cre;Nolz1^fl/fl, Foxd1Cre;Nolz1^fl/fl and En1Cre;Nolz1^fl/fl mutant embryos. Arrow in c' points to dopaminergic (DA) axon bundles crossing the midline. f Representative outline of coronal sections from E18.5 mouse striatum (top), hypothalamus (middle) and midbrain (bottom) indicating regions represented in b-e. Cx (cortex), Str (striatum), MFB (medial forebrain bundle), SN (substantia nigra). h,i: RNA in situ hybridization on coronal striatal sections of E15.5 embryos. j-k: Immunohistochemistry on E18.5 coronal sections. Scale bar (b-k): 200 um.

Copyright

This image is from Soleilhavoup C, Nat Commun 2020 Jun 19;11(1):3111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
b	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
b'	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
b''	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
c	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
c'	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
c''	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
d	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
d'	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
d''	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
e	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
e'	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
e''	MGI:8270447 (Slc6a3) MGI:8270488 (Zfp503)
h WT Rarb	MGI:8270637 (Rarb)
h WT Drd1	MGI:8270632 (Drd1)
h WT Ebf1	MGI:8270638 (Ebf1)
h WT Drd2	MGI:8270644 (Drd2)
h WT Grg4	MGI:8270648 (Tle4)
h WT Adora2A	MGI:8270649 (Adora2a)
h FoxG1-IresCre;Nolz1^fl/fl Drd1	MGI:8270632 (Drd1)
h FoxG1-IresCre;Nolz1^fl/fl Grg4	MGI:8270648 (Tle4)
h FoxG1-IresCre;Nolz1^fl/fl Drd2	MGI:8270644 (Drd2)
h FoxG1-IresCre;Nolz1^fl/fl Adora2A	MGI:8270649 (Adora2a)
h FoxG1-IresCre;Nolz1^fl/fl Rarb	MGI:8270637 (Rarb)
h FoxG1-IresCre;Nolz1^fl/fl Ebf1	MGI:8270638 (Ebf1)
i FoxG1-IresCre;Nolz1^fl/fl Netrin1	MGI:8270651 (Ntn1)
i FoxG1-IresCre;Nolz1^fl/fl EphB1	MGI:8270654 (Ephb1)
i FoxG1-IresCre;Nolz1^fl/fl Sema3A	MGI:8270653 (Sema3a)
k	MGI:8270622 (Ppp1r1b) MGI:8270447 (Slc6a3)
j	MGI:8270622 (Ppp1r1b) MGI:8270447 (Slc6a3)
i WT Netrin1	MGI:8270651 (Ntn1)
i WT EphB1	MGI:8270654 (Ephb1)
i WT Sema3A	MGI:8270653 (Sema3a)