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Rnf144b Gene Detail
Summary
  • Symbol
    Rnf144b
  • Name
    ring finger protein 144B
  • Synonyms
    E130105P19Rik, Ibrdc2, MGC:32473
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384986
    NCBI Gene: 218215
  • Alliance
    genome feature page
  • Transcription Start Sites
    25 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:47276196-47401470 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 24.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3462 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384986
 protein coding gene Chr13:47276132-47401470 (+)
129S1/SvImJ ENSMUSG00200035196
 protein coding gene Chr13:44534164-44659579 (+)
A/J ENSMUSG00195027949
 protein coding gene Chr13:43589225-43714666 (+)
AKR/J ENSMUSG00220008915
 protein coding gene Chr13:43395802-43521172 (+)
BALB/cJ ENSMUSG00180008015
 protein coding gene Chr13:43891635-44017053 (+)
C3H/HeJ ENSMUSG00175028349
 protein coding gene Chr13:43855787-43981199 (+)
C57BL/6NJ ENSMUSG00215005583
 protein coding gene Chr13:44020891-44146244 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018489
 protein coding gene Chr13:42376552-42505910 (+)
CAST/EiJ ENSTCUG00005029453
 protein coding gene Chr13:43921493-44047135 (+)
CBA/J ENSMUSG00210026645
 protein coding gene Chr13:43861297-43986717 (+)
DBA/2J ENSMUSG00185031560
 protein coding gene Chr13:44681377-44806806 (+)
FVB/NJ ENSMUSG00205009999
 protein coding gene Chr13:43641495-43766624 (+)
JF1/MsJ ENSUMUG00000010942
 protein coding gene Chr13:44199211-44324571 (+)
LP/J ENSMUSG00230025503
 protein coding gene Chr13:53997255-54122671 (+)
NOD/ShiLtJ ENSMUSG00190010866
 protein coding gene Chr13:44080009-44205438 (+)
NZO/HlLtJ ENSMUSG00225035535
 protein coding gene Chr13:47770563-47895932 (+)
PWK/PhJ ENSLUMG00010020306
 protein coding gene Chr13:43046273-43171613 (+)
SPRET/EiJ ENSMSPG00010028339
 protein coding gene Chr13:43157009-43279288 (+)
WSB/EiJ ENSIUOG00005025457
 protein coding gene Chr13:43233718-43359095 (+)



Homology
more
  • Human Ortholog
    RNF144B, ring finger protein 144B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF144B, ring finger protein 144B
  • Synonyms
    bA528A10.3, IBRDC2, p53RFP, PIR2
  • Links
    NCBI Gene ID: 255488
    UniProt: Q7Z419

  • Chr Location
    6p22.3; chr6:18387346-18468874 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice exhibit decreased susceptibility to encephalomyocarditis virus (EMCV) infection and higher survival rate and MEFs show impaired vesicular stomatitis virus replication.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    41
  • cDNA Data
    8
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 218215 NCBI Gene Model | MGI Sequence Detail 125275 C57BL/6J ±  kb
    transcript NM_146042 RefSeq | MGI Sequence Detail 4576 C57BL/6  
    polypeptide Q8BKD6 UniProt | EBI | MGI Sequence Detail 301 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 8
      Primer pair 1
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2444745
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 5
      Gene Ontology 9
      Phenotypes 15
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:366215 Rudat C, et al., PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes. Development. 2025 Apr 15;152(8)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory