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Rdh13 Gene Detail
Summary
  • Symbol
    Rdh13
  • Name
    retinol dehydrogenase 13 (all-trans and 9-cis)
  • Synonyms
    8430425D21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918732
    NCBI Gene: 108841
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4427769-4448648 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    800 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918732
 protein coding gene Chr7:4427769-4474279 (-)
129S1/SvImJ ENSMUSG00200037632
 protein coding gene Chr7:1162206-1183078 (-)
A/J ENSMUSG00195047664
 protein coding gene Chr7:1142217-1163102 (-)
AKR/J ENSMUSG00220025218
 protein coding gene Chr7:2933067-2953949 (+)
BALB/cJ ENSMUSG00180043602
 protein coding gene Chr7:1108182-1129056 (-)
C3H/HeJ ENSMUSG00175038559
 protein coding gene Chr7:1100586-1121463 (-)
C57BL/6NJ ENSMUSG00215040272
 protein coding gene Chr7:1145309-1166193 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029111
 protein coding gene Chr7:1114484-1138864 (-)
CAST/EiJ ENSTCUG00005027008
 protein coding gene Chr7:1321248-1342318 (-)
CBA/J ENSMUSG00210046408
 protein coding gene Chr7:1100576-1121458 (-)
DBA/2J ENSMUSG00185037986
 protein coding gene Chr7:1286054-1306933 (-)
FVB/NJ ENSMUSG00205039068
 protein coding gene Chr7:1089464-1110342 (-)
JF1/MsJ ENSUMUG00000029928
 protein coding gene Chr7:1369041-1410715 (-)
LP/J ENSMUSG00230034190
 protein coding gene Chr7:4307709-4328580 (-)
NOD/ShiLtJ ENSMUSG00190032429
 protein coding gene Chr7:1172515-1193392 (-)
NZO/HlLtJ ENSMUSG00225017197
 protein coding gene Chr7:2227514-2248372 (-)
PWK/PhJ ENSLUMG00010044900
 protein coding gene Chr7:4863889-4884902 (-)
SPRET/EiJ ENSMSPG00010037139
 protein coding gene Chr7:1303840-1323849 (-)
WSB/EiJ ENSIUOG00005050211
 protein coding gene Chr7:1121529-1142416 (-)



Homology
more
  • Human Ortholog
    RDH13, retinol dehydrogenase 13
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RDH13, retinol dehydrogenase 13
  • Synonyms
    SDR7C3
  • Links
    NCBI Gene ID: 112724
    UniProt: Q8NBN7

  • Chr Location
    19q13.42; chr19:55039103-55071291 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit disintegration of the outer-plus-inner-segment and outer nuclear layers, reduced amplitudes of a- and b-waves under scotopic conditions and swollen mitochondria in the inner segment following exposure to intense light.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    719
  • Tissues
    122
  • cDNA Data
    33
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000008435 Ensembl Gene Model | MGI Sequence Detail 20880 C57BL/6J ±  kb
    transcript ENSMUST00000008579 Ensembl | MGI Sequence Detail 3034 Not Applicable  
    polypeptide ENSMUSP00000008579 Ensembl | MGI Sequence Detail 334 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 34
      cDNA 33
      Primer pair 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 2
      Gene Ontology 10
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:281988 Cui X, et al., Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression levels. Front Med. 2019 Feb;13(1):104-111
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory