B6(Cg)-Psen2<tm1.1(PSEN2)Mdk> Tardbp<tm1.1(TARDBP)Mdk> Tmem106b<tm2.1(TMEM106B)Mdk> Snca<tm1.1(SNCA)Mdk> Isr(HSA17)1Mdk Psen1<tm1.1(PSEN1)Mdk> App<tm1.1(APP)Mdk>/J Strain Detail MGI Mouse MGI:8355281

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B6(Cg)-Psen2^{tm1.1(PSEN2)Mdk} Tardbp^{tm1.1(TARDBP)Mdk} Tmem106b^{tm2.1(TMEM106B)Mdk} Snca^{tm1.1(SNCA)Mdk} Isr(HSA17)1Mdk Psen1^{tm1.1(PSEN1)Mdk} App^{tm1.1(APP)Mdk}/J Strain Detail

Summary

Strain Name

B6(Cg)-Psen2^{tm1.1(PSEN2)Mdk} Tardbp^{tm1.1(TARDBP)Mdk} Tmem106b^{tm2.1(TMEM106B)Mdk} Snca^{tm1.1(SNCA)Mdk} Isr(HSA17)1Mdk Psen1^{tm1.1(PSEN1)Mdk} App^{tm1.1(APP)Mdk}/J
Attributes

chromosome aberration, mutant strain, targeted mutation
MGI ID

MGI:8355281

Other IDs

JAX:040829

7 associated mutations

Mutation Carried	Marker
App^{tm1.1(APP)Mdk}	App
Isr(HSA17)1Mdk	Isr(HSA17)1Mdk
Psen1^{tm1.1(PSEN1)Mdk}	Psen1
Psen2^{tm1.1(PSEN2)Mdk}	Psen2
Snca^{tm1.1(SNCA)Mdk}	Snca
Tardbp^{tm1.1(TARDBP)Mdk}	Tardbp
Tmem106b^{tm2.1(TMEM106B)Mdk}	Tmem106b

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
JAX:040829	JAX	B6(Cg)-Psen2^{tm1.1(PSEN2)Mdk} Tardbp^{tm1.1(TARDBP)Mdk} Tmem106b^{tm2.1(TMEM106B)Mdk} Snca^{tm1.1(SNCA)Mdk} Isr(HSA17)1Mdk Psen1^{tm1.1(PSEN1)Mdk} App^{tm1.1(APP)Mdk}/J	exact match to ID

Earliest

J:347607 Benzow K, et al., Gene replacement-Alzheimer's disease (GR-AD): Modeling the genetics of human dementias in mice. Alzheimers Dement. 2024 Apr;20(4):3080-3087
All

1

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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