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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Selp
selectin, platelet
MGI:98280
75 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Faslpr/Faslpr
Selptm1Bay/Selptm1Bay
MRL.Cg-Selptm1Bay Faslpr 		abnormal chemokine secretion J:127199
abnormal glomerular capillary endothelium morphology J:127199
abnormal leukocyte adhesion J:126009
abnormal renal glomerular capsule morphology J:127199
abnormal renal glomerulus morphology J:127199
dermatitis J:127199
expanded mesangial matrix J:127199
fused podocyte foot processes J:127199
glomerular crescent J:127199
glomerulonephritis J:127199
impaired leukocyte tethering or rolling J:126009
increased mesangial cell number J:127199
increased neutrophil cell number J:127199
kidney failure J:127199
podocyte foot process effacement J:127199
premature death J:127199
renal glomerular synechia J:127199
renal glomerulus fibrosis J:127199
renal necrosis J:127199
renal tubule atrophy J:127199
vascular inflammation J:127199
Icam1tm1Bay/Icam1tm1Bay
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6 		decreased acute inflammation J:112286
impaired neutrophil chemotaxis J:112286
increased neutrophil cell number J:112286
normal integument phenotype J:112286
skin edema J:112286
Icam1tm1Bay/Icam1tm1Bay
Selptm1Bay/Selptm1Bay
B6.129S7-Icam1tm1Bay Selptm1Bay/J 		edema J:119906
normal immune system phenotype J:119906
normal nervous system phenotype J:119906
Icam1tm1Bay/Icam1tm1Bay
Selptm1Bay/Selptm1Bay
either: B6.129S7-Selptm1Bay Icam1tm1Bay or (involves: 129S7/SvEvBrd * C57BL/6) 		impaired leukocyte tethering or rolling J:31374
Icam1tm1Bay/Icam1tm1Bay
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal leukocyte migration J:24239
increased neutrophil cell number J:24239
Seletm1Hyn/Seletm1Hyn
Selltm1Hyn/Selltm1Hyn
Selptm1Hyn/Selptm1Hyn
involves: 129S2/SvPas * C57BL/6 		impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased leukocyte cell number J:57973
increased monocyte cell number J:57973
increased neutrophil cell number J:57973
Seletm1Hyn/Seletm1Hyn
Selptm1Hyn/Selptm1Hyn
involves: 129S2/SvPas 		abnormal common myeloid progenitor cell morphology J:31626
abnormal cytokine level J:31626
abnormal definitive hematopoiesis J:31626
abnormal erythropoiesis J:31626
abnormal granulocyte differentiation J:31626
abnormal myelopoiesis J:31626
extramedullary hematopoiesis J:31626
impaired hematopoiesis J:31626
impaired leukocyte tethering or rolling J:31626
impaired neutrophil recruitment J:31626
increased circulating interleukin-3 level J:31626
increased eosinophil cell number J:31626
increased erythroid progenitor cell number J:31626
increased leukocyte cell number J:31626
increased lymphocyte cell number J:31626
increased monocyte cell number J:31626
increased neutrophil cell number J:31626
increased spleen red pulp amount J:31626
increased spleen weight J:31626
increased susceptibility to bacterial infection J:31626
premature death J:31626
spleen hyperplasia J:31626
Seletm1Hyn/Seletm1Hyn
Selptm1Hyn/Selptm1Hyn
involves: 129S2/SvPas * C57BL/6 		impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased leukocyte cell number J:57973
increased monocyte cell number J:57973
increased neutrophil cell number J:57973
Seletm2Alb/Seletm2Alb
Selltm2Alb/Selltm2Alb
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6 		abnormal cellular extravasation J:70682
abnormal cervical lymph node morphology J:70682
abnormal liver physiology J:106550
abnormal lung morphology J:70682
abnormal lung vasculature morphology J:70682
abnormal spleen B cell follicle morphology J:70682
abnormal spleen B cell follicle shape J:106550
abnormal spleen morphology J:70682
decreased circulating alanine transaminase level J:106550
decreased spleen B cell follicle number J:106550
enlarged lymph nodes J:70682
extramedullary hematopoiesis J:70682
hepatic necrosis J:106550
normal immune system phenotype J:70682
impaired leukocyte tethering or rolling J:70682
increased eosinophil cell number J:70682
increased leukocyte cell number J:70682
increased monocyte cell number J:70682
increased neutrophil cell number J:70682, J:106550
normal integument phenotype J:70682
lung inflammation J:70682
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6 		abnormal cytokine secretion J:70682
abnormal lung morphology J:70682
abnormal lung vasculature morphology J:70682
abnormal lymph node germinal center morphology J:70682
abnormal lymph node secondary follicle morphology J:70682
abnormal neutrophil physiology J:112286
abnormal spleen B cell follicle morphology J:70682
decreased acute inflammation J:112286
decreased spleen B cell follicle number J:70682
enlarged lymph nodes J:70682
extramedullary hematopoiesis J:70682
impaired leukocyte tethering or rolling J:70682
increased eosinophil cell number J:70682
increased leukocyte cell number J:70682
increased monocyte cell number J:70682
increased neutrophil cell number J:70682, J:112286
spontaneous skin ulceration J:70682, J:112286
Seletm2Alb/Seletm2Alb
Selptm1Bay/Selptm1Bay
involves: 129S7/SvEvBrd * C57BL/6J 		abnormal leukocyte cell number J:101979
abnormal pilomotor reflex J:101979
decreased locomotor activity J:101979
eye inflammation J:101979
head tilt J:101979
increased neutrophil cell number J:101979
increased susceptibility to bacterial infection J:101979
spinning J:101979
tremors J:101979
weight loss J:101979
Selltm3Hyn/Selltm3Hyn
Selptm1Hyn/Selptm1Hyn
involves: 129S2/SvPas * C57BL/6 		impaired eosinophil recruitment J:57973
impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
increased leukocyte cell number J:57973
increased neutrophil cell number J:57973
Selltm4Hyn/Selltm4Hyn
Selptm1Hyn/Selptm1Hyn
involves: 129S2/SvPas * C57BL/6 		impaired leukocyte tethering or rolling J:57973
impaired neutrophil recruitment J:57973
increased eosinophil cell number J:57973
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory