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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pdgfra
platelet derived growth factor receptor, alpha polypeptide
MGI:97530
81 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
2610005L07RikGt(ROSA)73Sor/2610005L07RikGt(ROSA)73Sor
Pdgfratm1Sor/Pdgfra+
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) 		abnormal ovary morphology J:142042
abnormal vascular smooth muscle morphology J:142042
anovulation J:142042
decreased circulating estradiol level J:142042
decreased corpora lutea number J:142042
decreased tertiary ovarian follicle number J:142042
decreased theca cell number J:142042
female infertility J:142042
small ovary J:142042
uterus hypoplasia J:142042
2610005L07RikGt(ROSA)73Sor/2610005L07RikGt(ROSA)73Sor
Pdgfratm2Sor/Pdgfra+
involves: 129S4/SvJaeSor 		abnormal frontal bone morphology J:117491
abnormal skeleton morphology J:117491
broad snout J:117491
short maxilla J:117491
short nasal bone J:117491
short premaxilla J:117491
short snout J:117491
Arid5bGt(ROSA)75Sor/Arid5bGt(ROSA)75Sor
Pdgfratm2Sor/Pdgfra+
involves: 129S4/SvJaeSor 		abnormal frontal bone morphology J:117491
abnormal skeleton morphology J:117491
broad snout J:117491
cleft palate J:117491
complete cleft palate J:117491
short maxilla J:117491
short nasal bone J:117491
short premaxilla J:117491
short snout J:117491
Cdkn2atm1Rdp/Cdkn2atm1Rdp
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Pdgfratm12Sor/Pdgfra+
involves: 129 * C57BL/6J * SJL 		increased fibrosarcoma incidence J:146617
increased sarcoma incidence J:146617
intestinal fibrosis J:146617
skeletal muscle interstitial fibrosis J:146617
skin fibrosis J:146617
Gata6tm2.2Sad/Gata6tm2.2Sad
Pdgfratm11(EGFP)Sor/Pdgfra+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ 		absent primitive endoderm J:213580
Hoxa5tm1Rob/Hoxa5tm1Rob
Pdgfratm11(EGFP)Sor/Pdgfra+
involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * MF1 		abnormal cell migration J:113378
abnormal pulmonary alveolar parenchyma morphology J:113378
Mir140tm1.1Tkob/Mir140tm1.1Tkob
Pdgfratm8Sor/Pdgfratm8Sor
Tg(Col2a1-cre)1Rsjo/0
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL 		abnormal skeleton morphology J:174096
decreased body size J:174096
decreased length of long bones J:174096
Myo1eGt(ROSA)74Sor/Myo1eGt(ROSA)74Sor
Pdgfratm2Sor/Pdgfra+
involves: 129S4/SvJaeSor 		anemia J:117491
Pdgfatm1Cbet/Pdgfatm2Cbet
Pdgfratm11(EGFP)Sor/Pdgfra+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 		abnormal lung morphology J:205009
abnormal pulmonary alveolus morphology J:205009
normal digestive/alimentary phenotype J:205009
emphysema J:205009
normal renal/urinary system phenotype J:205009
normal skeleton phenotype J:205009
Pdgfratm1.1(cre/Esr1*)Nshk/Pdgfra+
Runx1tm1Medv/Runx1tm1Medv
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj 		abnormal hematopoietic cell number J:193389
anemia J:193389
embryonic lethality during organogenesis, complete penetrance J:193389
pallor J:193389
Pdgfratm1Sor/Pdgfra+
Sgpl1Gt(ROSA)78Sor/Sgpl1Gt(ROSA)78Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) 		female infertility J:142042
male infertility J:142042
Pdgfratm1Sor/Pdgfra+
Plekha1Gt(ROSA)82Sor/Plekha1Gt(ROSA)82Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) 		abnormal ovary morphology J:142042
abnormal vascular smooth muscle morphology J:142042
absent corpus luteum J:142042
anovulation J:142042
decreased circulating estradiol level J:142042
decreased tertiary ovarian follicle number J:142042
decreased theca cell number J:142042
female infertility J:142042
male infertility J:142042
small ovary J:142042
uterus hypoplasia J:142042
Pdgfratm1Sor/Pdgfra+
TiparpGt(ROSA)79Sor/TiparpGt(ROSA)79Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) 		female infertility J:142042
Pdgfratm1Sor/Pdgfra+
Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) 		abnormal ovary morphology J:142042
abnormal vascular smooth muscle morphology J:142042
anovulation J:142042
decreased circulating estradiol level J:142042
decreased corpora lutea number J:142042
decreased tertiary ovarian follicle number J:142042
decreased theca cell number J:142042
female infertility J:142042
small ovary J:142042
uterus hypoplasia J:142042
Pdgfratm1Sor/Pdgfratm7Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) 		abnormal skeleton morphology J:73817
normal craniofacial phenotype J:73817
fetal bleb J:73817
Pdgfratm2Sor/Pdgfra+
Plekha1Gt(ROSA)82Sor/Plekha1Gt(ROSA)82Sor
involves: 129S4/SvJaeSor 		abnormal frontal bone morphology J:117491
abnormal skeleton morphology J:117491
broad snout J:117491
cleft palate J:117491
complete cleft palate J:117491
midline facial cleft J:117491
short maxilla J:117491
short nasal bone J:117491
short premaxilla J:117491
short snout J:117491
Pdgfratm2Sor/Pdgfra+
TiparpGt(ROSA)79Sor/TiparpGt(ROSA)79Sor
involves: 129S4/SvJaeSor 		abnormal frontal bone morphology J:117491
abnormal skeleton morphology J:117491
broad snout J:117491
short maxilla J:117491
short nasal bone J:117491
short premaxilla J:117491
short snout J:117491
Pdgfratm3Sor/Pdgfratm3Sor
either: 129S4/SvJaeSor-Pdgfratm3Sor or (involves: 129S4/SvJaeSor * C57BL/6) 		no abnormal phenotype detected J:67735
Pdgfratm5Sor/Pdgfratm5Sor
either: 129S4/SvJaeSor-Pdgfratm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J) 		abnormal cervical vertebrae morphology J:73817
abnormal myelination J:73817
abnormal pectoral girdle bone morphology J:73817
abnormal pulmonary alveolus morphology J:73817
abnormal sternum morphology J:73817
cleft secondary palate J:73817
decreased body size J:73817
emphysema J:73817
neonatal lethality, incomplete penetrance J:73817
palatal shelves fail to meet at midline J:73817
postnatal lethality, complete penetrance J:73817
respiratory failure J:73817
spina bifida J:73817
Pdgfratm5Sor/Pdgfratm5Sor
Pdgfrbtm3Sor/Pdgfrbtm3Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) 		embryonic growth retardation J:73817
failure of chorioallantoic fusion J:73817
fetal bleb J:73817
incomplete embryo turning J:73817
midline facial cleft J:73817
open neural tube J:73817
rib fusion J:73817
Pdgfratm5Sor/Pdgfratm11(EGFP)Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) 		abnormal oligodendrocyte morphology J:73817
decreased oligodendrocyte progenitor number J:73817
Pdgfratm6Sor/Pdgfratm6Sor
either: 129S4/SvJaeSor-Pdgfratm6Sor or (involves: 129S4/SvJaeSor * C57BL/6J) 		abnormal locomotor coordination J:73817
abnormal myelination J:73817
normal craniofacial phenotype J:73817
premature death J:73817
seizures J:73817
normal skeleton phenotype J:73817
tremors J:73817
Pdgfratm6Sor/Pdgfratm11(EGFP)Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) 		abnormal oligodendrocyte morphology J:73817
decreased oligodendrocyte progenitor number J:73817
Pdgfratm8Sor/Pdgfratm8Sor
Pdgfrbtm1Mdt/Pdgfrbtm1Mdt
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: C57BL/6 * CBA 		abnormal cardiac neural crest cell migration J:122584
abnormal thymus development J:122584
cleft palate J:122584
cyanosis J:122584
perinatal lethality, complete penetrance J:122584
persistent truncus arteriosus J:122584
retroesophageal right subclavian artery J:122584
thymus hypoplasia J:122584
ventricular septal defect J:122584
Pdgfratm8Sor/Pdgfratm8Sor
Pdgfrbtm11Sor/Pdgfrbtm11Sor
Tg(Nr5a1-cre)2Klp/0
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) 		abnormal adrenal cortex morphology J:142042
abnormal adrenal gland morphology J:142042
abnormal testis morphology J:142042
perinatal lethality, incomplete penetrance J:142042
small adrenal glands J:142042
small testis J:142042
testicular hemorrhage J:142042
Zfp950Gt(ROSA)76Sor/Zfp950Gt(ROSA)76Sor
Pdgfratm2Sor/Pdgfra+
involves: 129S4/SvJaeSor 		abnormal frontal bone morphology J:117491
abnormal skeleton morphology J:117491
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory