135 phenotypes from 12 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ Pdgfratm12Sor/Pdgfra+ involves: 129 * C57BL/6	abnormal cecum morphology	J:146617
	abnormal small intestine morphology	J:146617
	cardiac fibrosis	J:146617
	glomerulosclerosis	J:146617
	increased sarcoma incidence	J:146617
	intestinal fibrosis	J:146617
	intestine polyps	J:146617
	premature death	J:146617
	pulmonary fibrosis	J:146617
	renal glomerulus fibrosis	J:146617
	renal glomerulus hypertrophy	J:146617
	renal interstitial fibrosis	J:146617
	skeletal muscle interstitial fibrosis	J:146617
	tight skin	J:146617
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ Pdgfratm13Sor/Pdgfra+ involves: 129S4/SvJaeSor * C57BL/6	cardiac fibrosis	J:146617
	glomerulosclerosis	J:146617
	intestinal fibrosis	J:146617
	intestine polyps	J:146617
	renal glomerulus hypertrophy	J:146617
	skeletal muscle interstitial fibrosis	J:146617
	tight skin	J:146617
Pdgfratm1.1(cre/Esr1*)Nshk/Pdgfratm1.1(cre/Esr1*)Nshk involves: C57BL/6NCrlj * CBA/JNCrlj	normal hematopoietic system phenotype	J:193389
Pdgfratm1.1(EGFP/cre/ERT2)Hyma/Pdgfra+ involves: C57BL/6 * CBA/JNCrlj	normal cellular phenotype	J:221424
	normal growth/size/body region phenotype	J:221424
Pdgfratm1Sor/Pdgfra+ either: 129S4/SvJaeSor-Pdgfratm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)	normal pigmentation phenotype	J:41814
Pdgfratm1Sor/Pdgfratm1Sor either: 129S4/SvJaeSor-Pdgfratm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)	abnormal cervical vertebrae morphology	J:41814
	abnormal cranial neural crest cell morphology	J:41814
	abnormal frontal bone morphology	J:41814
	abnormal myotome development	J:41814
	abnormal myotome morphology	J:41814
	abnormal nasal bone morphology	J:41814
	abnormal neural tube morphology	J:41814
	abnormal parietal bone morphology	J:41814
	abnormal scapula morphology	J:41814
	abnormal spine curvature	J:41814
	abnormal sternum morphology	J:41814
	abnormal thoracic vertebrae morphology	J:41814
	abnormal vitelline vasculature morphology	J:41814
	absent roof plate	J:41814
	absent zygomatic bone	J:41814
	acromion hypoplasia	J:41814
	decreased embryo size	J:41814
	edema	J:41814
	embryonic growth retardation	J:41814
	failure of somite differentiation	J:41814
	fetal bleb	J:41814
	hemorrhage	J:41814
	herniated abdominal wall	J:41814
	impaired ossification of basisphenoid bone	J:41814
	incomplete embryo turning	J:41814
	incomplete rostral neuropore closure	J:41814
	increased apoptosis	J:41814
	lethality throughout fetal growth and development, incomplete penetrance	J:41814
	midline facial cleft	J:41814
	pericardial edema	J:41814
	normal pigmentation phenotype	J:41814
	rib bifurcation	J:41814
	rib fusion	J:41814
	skin edema	J:41814
	spina bifida	J:41814
	thin epidermis	J:41814
	wavy neural tube	J:41814
Pdgfratm1Sor/Pdgfratm1Sor involves: 129S4/SvJaeSor	short ureter	J:146617
Pdgfratm2Sor/Pdgfra+ either: 129S4/SvJaeSor-Pdgfratm2Sor or (involves: 129S4/SvJaeSor * C57BL/6J)	normal pigmentation phenotype	J:41814
Pdgfratm2Sor/Pdgfratm2Sor either: 129S4/SvJaeSor-Pdgfratm2Sor or (involves: 129S4/SvJaeSor * C57BL/6J)	abnormal cervical vertebrae morphology	J:41814
	abnormal cranial neural crest cell morphology	J:41814
	abnormal frontal bone morphology	J:41814
	abnormal myotome development	J:41814
	abnormal myotome morphology	J:41814
	abnormal nasal bone morphology	J:41814
	abnormal neural tube morphology	J:41814
	abnormal parietal bone morphology	J:41814
	abnormal scapula morphology	J:41814
	abnormal spine curvature	J:41814
	abnormal sternum morphology	J:41814
	abnormal thoracic vertebrae morphology	J:41814
	abnormal vitelline vasculature morphology	J:41814
	absent roof plate	J:41814
	absent zygomatic bone	J:41814
	acromion hypoplasia	J:41814
	decreased embryo size	J:41814
	edema	J:41814
	embryonic growth retardation	J:41814
	failure of somite differentiation	J:41814
	fetal bleb	J:41814
	hemorrhage	J:41814
	herniated abdominal wall	J:41814
	impaired ossification of basisphenoid bone	J:41814
	incomplete embryo turning	J:41814
	incomplete rostral neuropore closure	J:41814
	increased apoptosis	J:41814
	lethality throughout fetal growth and development, incomplete penetrance	J:41814
	midline facial cleft	J:41814
	pericardial edema	J:41814
	normal pigmentation phenotype	J:41814
	rib bifurcation	J:41814
	rib fusion	J:41814
	skin edema	J:41814
	spina bifida	J:41814
	thin epidermis	J:41814
	wavy neural tube	J:41814
Pdgfratm2Sor/Pdgfratm2Sor involves: 129S4/SvJaeSor	abnormal dorsal mesocardium morphology	J:157946
	abnormal heart atrium morphology	J:157946
	anomalous pulmonary venous connection	J:157946
	dual inferior vena cava	J:157946
	embryonic lethality during organogenesis, incomplete penetrance	J:157946
	pulmonary hypoplasia	J:157946
	pulmonary vein hypoplasia	J:157946
	total anomalous pulmonary venous connection	J:157946
Pdgfratm2Sor/Pdgfratm2Sor involves: 129S4/SvJaeSor * C57BL/6	abnormal diaphragm development	J:160875
	diaphragmatic hernia	J:160875
	embryonic lethality during organogenesis, incomplete penetrance	J:160875
	pulmonary hypoplasia	J:160875
	ventricular septal defect	J:160875
Pdgfratm8Sor/Pdgfratm8Sor Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ involves: 129S1/Sv * 129X1/SvJ	abnormal dorsal mesocardium morphology	J:157946
	dual inferior vena cava	J:157946
	total anomalous pulmonary venous connection	J:157946
Pdgfratm8Sor/Pdgfratm8Sor H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: C57BL/6 * CBA	delayed heart development	J:122584
	persistent truncus arteriosus	J:122584
	retroesophageal right subclavian artery	J:122584
	ventricular septal defect	J:122584
Pdgfratm8Sor/Pdgfratm8Sor H2az2Tg(Wnt1-cre)11Rth/H2az2+ Not Specified	abnormal frontal bone morphology	J:81153
	abnormal frontonasal prominence morphology	J:81153
	abnormal nasal bone morphology	J:81153
	abnormal nasal capsule morphology	J:81153
	abnormal vasculogenesis	J:81153
	hemorrhage	J:81153
	midline facial cleft	J:81153
	perimembraneous ventricular septal defect	J:81153
	persistent truncus arteriosus	J:81153
	postnatal lethality	J:81153
	short snout	J:81153
	small thymus	J:81153
Pdgfratm8Sor/Pdgfratm8Sor Hoxa3tm1(cre)Moon/Hoxa3+ Not Specified	abnormal dorsal mesocardium morphology	J:157946
	dual inferior vena cava	J:157946
	total anomalous pulmonary venous connection	J:157946
Pdgfratm8Sor/Pdgfratm8Sor Tg(Col2a1-cre)1Rsjo/0 involves: FVB/N	abnormal skeleton development	J:174096
	decreased body weight	J:174096
	decreased cranium height	J:174096
Pdgfratm8Sor/Pdgfratm8Sor Tg(Leftb-cre)1Hmd/0 Not Specified	abnormal dorsal mesocardium morphology	J:157946
	dual inferior vena cava	J:157946
	total anomalous pulmonary venous connection	J:157946
Pdgfratm8Sor/Pdgfratm8Sor Tg(Nr5a1-cre)2Klp/0 either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	abnormal ovarian follicle morphology	J:142042
	abnormal spermatocyte morphology	J:142042
	abnormal testis cord formation	J:142042
	abnormal testis morphology	J:142042
	abnormal testosterone level	J:142042
	anovulation	J:142042
	decreased circulating estradiol level	J:142042
	decreased Leydig cell number	J:142042
	decreased theca cell number	J:142042
	delayed fertility	J:142042
	oligozoospermia	J:142042
	normal reproductive system phenotype	J:142042
	small ovary	J:142042
	small testis	J:142042
	uterus hypoplasia	J:142042
Pdgfratm9(Pdgfra/Fgfr1)Sor/Pdgfra+ either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	abnormal pubis morphology	J:83560
	abnormal trophoblast layer morphology	J:83560
	cleft palate	J:83560
	ectopic cranial bone	J:83560
	enlarged placenta	J:83560
	open neural tube	J:83560
	polydactyly	J:83560
	rib fusion	J:83560
	spina bifida	J:83560
Pdgfratm9(Pdgfra/Fgfr1)Sor/Pdgfratm11(EGFP)Sor either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	embryonic lethality during organogenesis, complete penetrance	J:83560
	failure of initiation of embryo turning	J:83560
	failure of somite differentiation	J:83560
Pdgfratm10(Pdgfra/tor)Sor/Pdgfratm10(Pdgfra/tor)Sor either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	abnormal heart septum morphology	J:83560
	abnormal rib joint morphology	J:83560
	absent sternum	J:83560
	normal cardiovascular system phenotype	J:83560
	cleft palate	J:83560
	hydrops fetalis	J:83560
	lethality throughout fetal growth and development, incomplete penetrance	J:83560
	midline facial cleft	J:83560
	open neural tube	J:83560
	spina bifida	J:83560
Pdgfratm10(Pdgfra/tor)Sor/Pdgfratm11(EGFP)Sor either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	abnormal placenta development	J:83560
	prenatal lethality, complete penetrance	J:83560
Pdgfratm11(EGFP)Sor/Pdgfratm11(EGFP)Sor either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	abnormal placenta development	J:83560
	abnormal placenta vasculature	J:83560
	prenatal lethality	J:83560
Pdgfratm12.1Sor/Pdgfra+ involves: 129 * C57BL/6	abnormal immune system organ morphology	J:146617
	abnormal kidney pelvis morphology	J:146617
	abnormal lung development	J:146617
	abnormal mesenchyme morphology	J:146617
	abnormal rib morphology	J:146617
	abnormal sternum morphology	J:146617
	abnormal stomach morphology	J:146617
	abnormal ureter development	J:146617
	abnormal ureter morphology	J:146617
	abnormal ureter smooth muscle morphology	J:146617
	edema	J:146617
	esophagus hyperplasia	J:146617
	increased cell proliferation	J:146617
	increased embryo size	J:146617
	increased fetal size	J:146617
	increased fibroblast chemotaxis	J:146617
	increased fibroblast proliferation	J:146617
	increased mesenchymal cell proliferation involved in lung development	J:146617
	postnatal lethality, complete penetrance	J:146617
	pulmonary hyperplasia	J:146617
	ureter obstruction	J:146617
	wide sternum	J:146617
Pdgfratm13.1Sor/Pdgfra+ involves: 129 * C57BL/6	abnormal kidney pelvis morphology	J:146617
	abnormal stomach morphology	J:146617
	abnormal ureter morphology	J:146617
	abnormal ureter smooth muscle morphology	J:146617
	dilated ureter	J:146617
	esophagus hyperplasia	J:146617
	hydronephrosis	J:146617
	increased fibroblast proliferation	J:146617
	postnatal lethality, incomplete penetrance	J:146617
	ureter obstruction	J:146617