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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Npr2
natriuretic peptide receptor 2
MGI:97372
106 phenotypes from 11 alleles in 15 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Npr2cn-2J/Npr2cn-2J
B6;CBACa Aw-J/A-Npr2cn-2J/GrsrJ
abnormal female meiosis J:164870
Npr2cn-2J/Npr2cn-2J
B6;CBACa-Aw-J/A-Kcnj6wv/+
disorganized long bone epiphyseal plate J:72465
increased diameter of femur J:72465
round head J:72465
short femur J:72465
normal skeleton phenotype J:72465
splayed ribs J:72465
Npr2cn-3J/Npr2cn-3J
MRL/MpJ-Npr2cn-3J/GrsrJ
decreased litter size J:170669
disproportionate dwarf J:170669
micromelia J:170669
reduced fertility J:170669
short snout J:170669
short tail J:170669
Npr2cn/Npr2cn
AKR/J
abnormal axial skeleton morphology J:5109
abnormal blood circulation J:5109
abnormal body weight J:5109
abnormal bone trabecula morphology J:5109
abnormal craniofacial morphology J:5109
abnormal long bone epiphyseal plate morphology J:5109
abnormal long bone epiphyseal plate proliferative zone J:5109
abnormal nose morphology J:5109
abnormal pelvic girdle bone morphology J:5109
abnormal postnatal growth/weight/body size J:5109
brachydactyly J:5109
cyanosis J:5109
decreased body weight J:5109
decreased cranium length J:5109
decreased cranium width J:5109
decreased length of long bones J:5109
decreased long bone epiphyseal plate size J:5109
decreased width of hypertrophic chondrocyte zone J:5109
distended abdomen J:5109
domed cranium J:5109
malocclusion J:5109
postnatal growth retardation J:5109
postnatal lethality, incomplete penetrance J:5109
premature death J:5109
reduced fertility J:5109
short femur J:5109
short humerus J:5109
short limbs J:5109
short maxilla J:5109
short radius J:5109
short scapula J:5109
short tail J:5109
short tibia J:5109
short ulna J:5109
short vertebral column J:5109
small spleen J:5109
thick tail J:5109
Npr2cn/Npr2cn
involves: AKR/J
abnormal sensory neuron innervation pattern J:153212
abnormal skeleton development J:5934
abnormal spinal cord dorsal column morphology J:153212
Npr2cn/Npr2cn
Not Specified
abnormal basicranium morphology J:5849
abnormal chondrocyte morphology J:15335
abnormal long bone epiphyseal plate morphology J:8099
abnormal mandibular condyloid process morphology J:5849
Npr2cn/Npr2slw
involves: AKR/J * C57BL/6 * DDY
disproportionate dwarf J:129973
Npr2pwe/Npr2pwe
involves: C3H/HeJ * C57BL/6 * CAST * NAW/WI
normal mortality/aging J:188839
Npr2pwe/Npr2pwe
involves: C3H/HeJ * C57BL/6 * NAW/WI
abnormal cervical atlas morphology J:188839
abnormal endochondral bone ossification J:188839
abnormal long bone epiphyseal plate morphology J:188839
abnormal long bone epiphyseal plate proliferative zone J:188839
abnormal long bone hypertrophic chondrocyte zone J:188839
abnormal oogenesis J:188839
decreased body length J:188839
decreased body weight J:188839
decreased survivor rate J:188839
delayed vaginal opening J:188839
disproportionate dwarf J:188839
domed cranium J:188839
female infertility J:188839
malocclusion J:188839
postnatal growth retardation J:188839
reduced male fertility J:188839
short femur J:188839
short humerus J:188839
short snout J:188839
Npr2slw/Npr2slw
involves: C57BL/6 * DDY
abnormal digestive system physiology J:163374
abnormal endochondral bone ossification J:129973
abnormal intestine physiology J:163374
abnormal pyloric sphincter morphology J:163374
chondrodystrophy J:129973
decreased body length J:129973
disproportionate dwarf J:129973
domed cranium J:129973
embryonic lethality, incomplete penetrance J:129973
enlarged interparietal bone J:129973
enlarged parietal bone J:129973
impaired gastric peristalsis J:163374
impaired muscle relaxation J:163374
meteorism J:163374
postnatal lethality, incomplete penetrance J:163374
short tail J:129973
small nasal bone J:129973
small supraoccipital bone J:129973
Npr2tm1Fgr/Npr2tm1Fgr
involves: 129P2/OlaHsd * C57BL/6J
abnormal dorsal root ganglion morphology J:205571
abnormal trigeminal nerve morphology J:205571
decreased body size J:205571
Npr2tm1Gar/Npr2+
involves: 129S6/SvEvTac * C57BL/6
decreased body length J:94718
Npr2tm1Gar/Npr2tm1Gar
involves: 129S6/SvEvTac * C57BL/6
abnormal cranium morphology J:94718
abnormal skeleton development J:94718
abnormal uterus morphology J:94718
absent corpus luteum J:94718
absent estrous cycle J:94718
normal cardiovascular system phenotype J:94718
decreased body size J:94718
decreased long bone epiphyseal plate size J:94718
decreased width of hypertrophic chondrocyte zone J:94718
female infertility J:94718
limb grasping J:94718
long incisors J:94718
long lower incisors J:94718
long upper incisors J:94718
malocclusion J:94718
postnatal growth retardation J:94718
premature death J:94718
small ovary J:94718
small uterus J:94718
thin endometrium J:94718
thin myometrium J:94718
thin uterine horn J:94718
Npr2tm2.1(cre/ERT2)Fgr/Npr2cn
Tg(CAG-Bgeo/ALPP)1Lbe/0
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * AKR/J * C57BL/6J
abnormal cranial nerve morphology J:205571
abnormal dorsal root ganglion morphology J:205571
normal nervous system phenotype J:205571
Tg(Col2a1-Npr2*B1)2Gar/0
involves: 129 * C57BL/6 * SJL
no abnormal phenotype detected J:124908
Tg(Col2a1-Npr2*B2)25-4Gar/0
involves: 129 * C57BL/6 * SJL
decreased body length J:94718
Tg(Col11a2-Npr2*)28Keoz/0
involves: C57BL/6
abnormal locomotor behavior J:189658
abnormal long bone hypertrophic chondrocyte zone J:189658
abnormal long bone morphology J:189658
abnormal neurocranium morphology J:189658
abnormal phalanx morphology J:189658
abnormal vertebrae morphology J:189658
disorganized long bone epiphyseal plate J:189658
increased body length J:189658
increased long bone epiphyseal plate size J:189658
kyphosis J:189658
long femur J:189658
long tail J:189658
long tibia J:189658

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory