68 phenotypes from 7 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Engem1(IMPC)Mbp/Eng+ C57BL/6N-Engem1(IMPC)Mbp/MbpMmucd	abnormal caudal vertebrae morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal placenta morphology	J:211773
	increased neutrophil cell number	J:211773
	small kidney	J:211773
Engem1(IMPC)Mbp/Engem1(IMPC)Mbp C57BL/6N-Engem1(IMPC)Mbp/MbpMmucd	abnormal heart morphology	J:211773
	abnormal neural tube morphology	J:211773
	abnormal pharyngeal arch morphology	J:211773
	abnormal somite shape	J:211773
	abnormal visceral yolk sac morphology	J:211773
	abnormal vitelline vasculature morphology	J:211773
	embryonic growth retardation	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
EngGt(Betageo)1Jrt/EngGt(Betageo)1Jrt either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * ICR)	no abnormal phenotype detected	J:92259
Engtm1Dyl/Engtm1Dyl involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal carotid artery morphology	J:55403
	abnormal dorsal aorta morphology	J:55403
	abnormal intersomitic vessel morphology	J:55403
	abnormal perineural vascular plexus morphology	J:55403
	abnormal vascular development	J:55403
	abnormal vascular smooth muscle morphology	J:55403
	abnormal vitelline vasculature morphology	J:55403
	blood vessel atresia	J:55403
	decreased angiogenesis	J:55403
	decreased embryo size	J:55403
	embryonic lethality during organogenesis, complete penetrance	J:55403
	failure of heart looping	J:55403
	incomplete somite formation	J:55403
	pericardial effusion	J:55403
Engtm1Hma/Eng+ 129P2/OlaHsd-Engtm1Hma	abnormal blood vessel morphology	J:73415
	abnormal vascular smooth muscle morphology	J:73415
Engtm1Hma/Engtm1Hma involves: 129P2/OlaHsd	abnormal vascular smooth muscle morphology	J:98373
Engtm1Hma/Engtm1Hma involves: 129P2/OlaHsd * C57BL/6J	abnormal capillary morphology	J:73415
	abnormal cardiac outflow tract development	J:73415
	abnormal dorsal aorta morphology	J:73415
	abnormal embryonic hematopoiesis	J:73415
	abnormal heart development	J:73415
	abnormal heart looping	J:73415
	abnormal vitelline vasculature morphology	J:73415
	anemia	J:73415
	decreased embryo size	J:73415
	embryonic growth retardation	J:73415
	embryonic lethality during organogenesis, complete penetrance	J:73415
	increased heart ventricle size	J:73415
	pericardial effusion	J:73415
	thin myocardium	J:73415
Engtm1Hma/Engtm2.1Hma involves: 129P2/OlaHsd * C57BL/6	normal mortality/aging	J:121898
Engtm1Mle/Eng+ 129P2/OlaHsd-Engtm1Mle	ear telangiectasia	J:58502
	hemorrhage	J:58502
	premature death	J:58502
	tail telangiectasia	J:58502
Engtm1Mle/Eng+ involves: 129P2/OlaHsd * C57BL/6	ear telangiectasia	J:58502
	hemorrhage	J:58502
	internal hemorrhage	J:58502
	neck telangiectasia	J:58502
	respiratory distress	J:58502
	ruffled hair	J:58502
	tail telangiectasia	J:58502
	weight loss	J:58502
Engtm1Mle/Eng+ involves: 129P2/OlaHsd * C57BL/6 * CD-1	normal cardiovascular system phenotype	J:58502
Engtm1Mle/Engtm1Mle involves: 129P2/OlaHsd * C57BL/6	abnormal blood vessel morphology	J:58502
	abnormal craniofacial development	J:58502
	abnormal endocardium morphology	J:58502
	abnormal heart development	J:58502
	abnormal pharyngeal arch morphology	J:58502
	abnormal visceral yolk sac blood island morphology	J:58502
	abnormal vitelline vasculature morphology	J:58502
	absent heartbeat	J:58502
	absent vitelline blood vessels	J:58502
	embryo tissue necrosis	J:58502
	embryonic growth retardation	J:58502
	embryonic lethality during organogenesis, complete penetrance	J:58502
	enlarged heart	J:58502
	hemoperitoneum	J:58502
	microcephaly	J:58502
	pericardial edema	J:58502
Engtm2.1Hma/Engtm2.1Hma involves: 129P2/OlaHsd	cerebral arteriovenous malformation	J:196810
Engtm2.1Hma/Engtm2.1Hma involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:121898
Engtm2.1Hma/Engtm2.1Hma Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal vascular wound healing	J:212952, J:227170
	arteriovenous malformation	J:212952, J:227170
	decreased locomotor activity	J:227170
	dehydration	J:227170
	diarrhea	J:227170
	hemorrhage	J:212952
	moribund	J:227170
Engtm2.1Hma/Engtm2.1Hma Lyz2tm1(cre)Ifo/Lyz2+ involves: 129P2/OlaHsd	normal cardiovascular system phenotype	J:212952
Engtm2.1Hma/Engtm2.1Hma Tg(Myh11-icre/ERT2)1Soff/0 involves: 129P2/OlaHsd * FVB/N	normal cardiovascular system phenotype	J:227170
Engtm2.1Hma/Engtm2.1Hma Tg(Tagln-cre)1Her/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal blood vessel morphology	J:212952
	arteriovenous malformation	J:212952
	gastrointestinal arteriovenous malformation	J:212952
	hemorrhage	J:212952
	premature death	J:212952
Engtm2.1Hma/Engtm2.1Hma Tg(Tal1-cre/ERT)1Jrg/0 involves: 129P2/OlaHsd * C57BL/6	abnormal vascular wound healing	J:227170
	arteriovenous malformation	J:227170
Engtm2.2Hma/Engtm2.2Hma involves: 129P2/OlaHsd * BALB/c * C57BL/6	abnormal embryo development	J:121898
	abnormal vitelline vasculature morphology	J:121898
	prenatal lethality, complete penetrance	J:121898