Eng^{Gt(Betageo)1Jrt}
Gene trapped Allele Detail

Summary

• Symbol: Eng^{Gt(Betageo)1Jrt}
• Name: endoglin; gene trap 1, Janet Rossant
• MGI ID: MGI:3052745
• Gene: Eng Location: Chr2:32536607-32572681 bp, + strand Genetic Position: Chr2, 22.09 cM
• Alliance: Eng^{Gt(Betageo)1Jrt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92259
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector containing IRES-Betageo-pA was inserted in the 3' UTR. LacZ expression was detected in spindle shaped cells of differentiated ES cells. 3' and 5' RACE indicate that the endogenous coding region is not disrupted (J:92259)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eng Mutation: 41 strains or lines available

References

• Original: J:92259 Hirashima M, et al., Gene-trap expression screening to identify endothelial-specific genes. Blood. 2004 Aug 1;104(3):711-8
• All: 1 reference(s)