59 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ay/a Ednrbs/Ednrbs Not Specified	variable body spotting	J:12954
Ednratm1Ywa/Ednratm1Ywa Ednrbtm1Ywa/Ednrbtm1Ywa involves: 129S7/SvEvBrd	abnormal artery morphology	J:46640
	pericardial effusion	J:46640
	prenatal lethality	J:46640
Ednrbs-3CHLo/Ednrbs-3CHLo involves: 101/Rl * C3H/Rl	megacolon	J:44601, J:100221
	postnatal lethality, complete penetrance	J:44601, J:100221
	white spotting	J:44601, J:100221
Ednrbs-15DttMb/Ednrb+ Mycbp2tm1.1Adia/Mycbp2+ involves: 101/Rl * C3H/Rl * C57BL/6 * FVB/N	abnormal nervous system morphology	J:125702
Ednrbs-24Pub/Ednrb+ Mycbp2m274-4Tpo/Mycbp2+ involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	neonatal lethality, complete penetrance	J:149893
	respiratory distress	J:149893
Ednrbs-24Pub/Ednrb+ m128-7Tpo/m128-7Tpo+ involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	abnormal direction of heart looping	J:149893
	abnormal head morphology	J:149893
	abnormal pharyngeal arch morphology	J:149893
	abnormal vitelline vasculature morphology	J:149893
	embryonic lethality, complete penetrance	J:149893
	enlarged pericardium	J:149893
	hemopericardium	J:149893
	incomplete embryo turning	J:149893
Ednrbs-24Pub/Ednrb+ m174-16Tpo/m174-16Tpo+ involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	lethality throughout fetal growth and development, complete penetrance	J:149893
Ednrbs-24Pub/Ednrb+ m183-15Tpo/m183-15Tpo+ involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	embryonic lethality between implantation and somite formation, complete penetrance	J:149893
Ednrbs-24Pub/Ednrb+ m251-2Tpo/m251-2Tpo+ involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	preweaning lethality, complete penetrance	J:149893
Ednrbs-24Pub/Ednrb+ m283-1Tpo/m283-1Tpo+ involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	preweaning lethality, complete penetrance	J:149893
Ednrbs-24Pub/Ednrbs-24Pub m289-5Tpo/m289-5Tpo+ involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	preweaning lethality, complete penetrance	J:149893
Ednrbs-31Pub/Ednrb+ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrbs-31Pub/Ednrbs-31Pub involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrbs-36Pub/Ednrb+ Spry2tm1.1Mrt/Spry2+ involves: 101/Rl * 129P2/OlaHsd * C3H/Rl * C57BL/6J	abnormal palatal rugae morphology	J:125229
	cleft secondary palate	J:125229
Ednrbs-36Pub/Ednrbs-36Pub Tg(Spry2)2Tpo/0 B6.Cg-Ednrbs-36Pub Tg(Spry2)2Tpo	abnormal palate bone morphology	J:125229
	cleft secondary palate	J:125229
	normal craniofacial phenotype	J:125229
	maxillary shelf hypoplasia	J:125229
Ednrbs-36Pub/Ednrbs-36Pub Tg(Spry2)69Tpo/0 B6.Cg-Ednrbs-36Pub Tg(Spry2)69Tpo	abnormal palate bone morphology	J:125229
	cleft secondary palate	J:125229
	normal craniofacial phenotype	J:125229
	maxillary shelf hypoplasia	J:125229
Ednrbs/Ednrbs-3CHLo involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrbs/Ednrbs-31Pub involves: 101/Rl * C3H/Rl	decreased body size	J:100221
	white spotting	J:100221
Ednrbs/Ednrbs Lystbg-slt/Lystbg-slt involves: C57BL/10Ch * Y257/Ch	abnormal eye pigmentation	J:25388
Ednrbs/Ednrbs Mc1re/Mc1re Not Specified	white spotting	J:5110
	yellow coat color	J:5110
Ednrbtm1.1Nat/Ednrbtm1.2Nat Igs1tm11(CAG-Bgeo,-Edn2)Nat/Igs1+ Tg(Pax6-cre,GFP)2Pgr/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal retina vasculature morphology	J:201133
Ednrbtm1Nrd/Ednrbtm1Nrd Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J	abnormal enteric neural crest cell migration	J:140320
	aganglionic megacolon	J:140320
	distended abdomen	J:140320
	premature death	J:140320
	slow postnatal weight gain	J:140320
	white spotting	J:140320
Ednrbtm1Nrd/Ednrbtm1Nrd Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J	abnormal mature B cell number	J:233811
	abnormal Peyer's patch morphology	J:233811
	abnormal spleen morphology	J:233811
	abnormal splenic cell ratio	J:233811
	decreased B cell number	J:233811
	decreased germinal center B cell number	J:233811
	decreased IgA level	J:233811
	decreased marginal zone B cell number	J:233811
	decreased spleen red pulp amount	J:233811
	decreased spleen weight	J:233811
	decreased spleen white pulp amount	J:233811
	large intestinal inflammation	J:233811
	small Peyer's patches	J:233811
	small spleen	J:233811
Ednrbtm1Nrd/Ednrbtm1Nrd Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Tg(Tyr-cre/ERT2)13Bos/0 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J	abnormal coat/hair pigmentation	J:231435
	abnormal hair follicle melanocyte morphology	J:231435
	abnormal melanocyte proliferation	J:231435
	absent hair follicle melanin granules	J:231435
	decreased melanocyte number	J:231435
	reduced hair shaft melanin granule number	J:231435
Ednrbtm1Ywa/Ednrb+ Tg(Mt1-RET)304Ina/0 involves: 129S7/SvEvBrd * BALB/c * C57BL/6	decreased tumor-free survival time	J:155735
	increased melanoma incidence	J:155735
	increased metastatic potential	J:155735