Mycbp2^m274-4Tpo
Chemically induced Allele Detail

Summary

• Symbol: Mycbp2^m274-4Tpo
• Name: MYC binding protein 2, E3 ubiquitin protein ligase; mutation 274-4, Timothy P O'Brien
• MGI ID: MGI:3849603
• Synonyms: Phr^274-4
• Gene: Mycbp2 Location: Chr14:103350847-103584250 bp, - strand Genetic Position: Chr14, 51.79 cM
• Alliance: Mycbp2^m274-4Tpo page

Small size of Mycbp2^m274-4Tpo/Mycbp2^m274-4Tpo mice at birth

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: SSL/LeJ

Mutation description

Allele Type: Chemically induced (ENU) Mutation: Single point mutation Mutation details: ENU mutagenesis induced a T to A transversion at position 2599 in exon 15. This point mutation results in termination of protein translation instead of coding for a cystein at position 772 (C772X). The protein product is truncated after the second RCC1 homology domain. (J:149893) Inheritance: Recessive

Schematic of the ENU-induced Mycbp2^m274-4Tpo mutation

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mycbp2 Mutation: 223 strains or lines available

Notes

Strain of origin for this mutation was determined by its close linkage to Ednrb^s (J:149893).

References

• Original: J:149893 Hagarman JA, et al., An essential gene mutagenesis screen across the highly conserved piebald deletion region of mouse chromosome 14. Genesis. 2009 Jun;47(6):392-403
• All: 1 reference(s)