70 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nfatc1tm1Glm/Nfatc1tm1Glm B6.129S2-Nfatc1tm1Glm	abnormal cardiac outflow tract development	J:185683
	abnormal semilunar valve morphology	J:185683
	decreased atrioventricular cushion size	J:185683
Nfatc1tm1Glm/Nfatc1tm1Glm involves: 129S2/SvPas	abnormal blood circulation	J:99892
	abnormal cardiovascular system physiology	J:46398
	abnormal heart morphology	J:46398
	abnormal semilunar valve morphology	J:46398
	absent aortic valve cusps	J:46398
	absent pulmonary valve cusps	J:46398
	edema	J:46398
	gastrointestinal hemorrhage	J:46398
	lethality throughout fetal growth and development, complete penetrance	J:46398
	pallor	J:46398
	pericardial effusion	J:46398
	semilunar valve regurgitation	J:99892
	ventricular septal defect	J:46398
Nfatc1tm1Glm/Nfatc1tm2Glm chimera involves: 129S2/SvPas	abnormal B cell physiology	J:78376
	abnormal immune system physiology	J:78376
	abnormal immunoglobulin level	J:78376
	abnormal interferon-gamma secretion	J:78376
	abnormal interleukin-2 secretion	J:78376
	abnormal lymphocyte cell number	J:78376
	abnormal lymphocyte physiology	J:78376
	abnormal T cell physiology	J:78376
	abnormal T-helper 2 physiology	J:78376
	decreased double-positive T cell number	J:78376
	decreased IgE level	J:78376
	decreased IgG1 level	J:78376
	decreased IgG2b level	J:78376
	decreased IgG3 level	J:78376
	decreased immunoglobulin level	J:78376
	decreased interleukin-4 secretion	J:78376
	decreased lymphocyte cell number	J:78376
	increased double-negative T cell number	J:78376
	increased IgA level	J:78376
	increased IgG2a level	J:78376
	increased IgM level	J:78376
	increased immunoglobulin level	J:78376
Nfatc1tm1Mak/Nfatc1tm1Mak involves: 129P2/OlaHsd * C57BL/6	abnormal cardiac outflow tract development	J:46399
	abnormal interventricular septum morphology	J:46399
	abnormal mitral valve cusp morphology	J:46399
	abnormal mitral valve development	J:46399
	abnormal semilunar valve development	J:46399
	abnormal tricuspid valve cusp morphology	J:46399
	abnormal tricuspid valve development	J:46399
	anemia	J:46399
	cardiac hypertrophy	J:46399
	edema	J:46399
	embryo tissue necrosis	J:46399
	lethality throughout fetal growth and development, complete penetrance	J:46399
Nfatc1tm1Rao/Nfatc1tm1Rao Cd79atm1(cre)Reth/Cd79a+ involves: BALB/c	abnormal B cell physiology	J:177319
	abnormal class switch recombination	J:177319
	abnormal marginal zone B cell physiology	J:177319
	decreased B cell number	J:177319
	decreased B cell proliferation	J:177319
	decreased B-1a cell number	J:177319
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:177319
	increased B cell apoptosis	J:177319
Nfatc1tm1Rao/Nfatc1tm1Rao Tg(Fcer2a-cre)5Mbu/0 involves: C57BL/6 * CBA	abnormal B cell physiology	J:177319
	abnormal class switch recombination	J:177319
	decreased B cell proliferation	J:177319
	decreased IgG2a level	J:177319
	decreased IgG3 level	J:177319
	decreased IgM level	J:177319
	decreased interleukin-2 secretion	J:177319
	increased IgM level	J:177319
	increased interleukin-10 secretion	J:177319
Nfatc1tm3Glm/Nfatc1tm3Glm Lyz2tm1(cre)Ifo/Lyz2+ involves: 129P2/OlaHsd * C57BL/6	normal skeleton phenotype	J:144598
Nfatc1tm3Glm/Nfatc1tm3Glm Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	abnormal endochondral bone ossification	J:144598
	abnormal mandibular condyloid process morphology	J:144598
	abnormal osteoclast differentiation	J:144598
	absent lower incisors	J:144598
	decreased length of long bones	J:144598
	decreased osteoclast cell number	J:144598
	increased width of hypertrophic chondrocyte zone	J:144598
	long upper incisors	J:144598
	osteopetrosis	J:144598
	short femur	J:144598
	short lower incisors	J:144598
	short tibia	J:144598
Nfatc1tm3Glm/Nfatc1tm3Glm Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/? involves: C57BL/6 * CD-1	normal skeleton phenotype	J:144598