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Hoxd9
Gene Detail
Symbol

Name
ID
Member of
Hoxd9
homeobox D9
MGI:96210
Hoxd cluster
Synonyms
Hox-4.4, Hox-5.2
Feature Type
protein coding gene
Genetic Map
Chromosome 2
44.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
Chr2:74697727-74700208 bp, + strand
From VEGA annotation of GRCm38

  2482 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8409  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: homeobox protein, Hox9 type
Gene Tree: Hoxd9

Human
homologs
Human Homolog HOXD9, homeobox D9
NCBI Gene ID 3235
neXtProt AC  NX_P28356
Human Synonyms  HOX4, Hox-4.3, HOX4C, Hox-5.2
Human Chr (Location)  2q31.1; chr2:176122685-176124917 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Targeted(26)
Genomic Mutations involving Hoxd9 (21)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted mutation exhibit anterior transformation of lumbar, sacral, and caudal vertebrae with abnormal humerus morphology.
 
Interactions
Hoxd9 interacts with 131 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (59 records)
Data Summary: Results (429)    Tissues (162)    Images (44)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 226
RT-PCR 203
cDNA source data(20)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(44) Genomic(13) cDNA(20) Primer pair(10) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000016552 (Evidence)
Ensembl Gene ModelENSMUSG00000043342 (Evidence)
Entrez Gene15438 (Evidence)
UniGene26544
DFCITC1585017
DoTSDT.489308
NIA Mouse Gene IndexU124010
Consensus CDS ProjectCCDS16142.1
International Mouse Knockout Project StatusHoxd9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016552 VEGA Gene Model | MGI Sequence Detail 2482 C57BL/6J ±  kb
transcript OTTMUST00000040004 VEGA | MGI Sequence Detail 2136 Not Applicable 
polypeptide OTTMUSP00000017844 VEGA | MGI Sequence Detail 339 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms
PCR(2) : SNPs within 2kb(3 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017970 Homeobox, conserved site
InterPro IPR017112 Homeobox protein Hox9
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
InterPro IPR006711 Hox9, N-terminal activation domain
Protein Ontology PR:000008724 homeobox protein Hox-D9
References
(Earliest) J:9875 Oliver G, et al., Complementary homeo protein gradients in developing limb buds. Genes Dev. 1989 May;3(5):641-50
(Latest) J:204375 Sheth R, et al., "Self-regulation," a new facet of Hox genes' function. Dev Dyn. 2014 Jan;243(1):182-91
All references(99)
Other
accession IDs
MGD-MRK-10851, MGD-MRK-10859, MGD-MRK-10911

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory