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H2-Ea-ps Pseudogene Detail
Summary
  • Symbol
    H2-Ea-ps
  • Name
    histocompatibility 2, class II antigen E alpha, pseudogene
  • Synonyms
    H-2Ea, Ia3, Ia-3, I-Ealpha
Location & Maps
more
  • Sequence Map
    Chr17:34342933-34344643 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1711 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    31 experiments
  • Sequence Tag for
Homology
more
  • Human Ortholog
    HLA-DRA, major histocompatibility complex, class II, DR alpha
  • Vertebrate Orthologs
    8
  • Human Ortholog
    HLA-DRA, major histocompatibility complex, class II, DR alpha
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HLA-DRA1
  • Links
    NCBI Gene ID: 3122
    neXtProt AC: NX_P01903

  • Chr Location
    6p21.32; chr6:32439842-32445046 (+)  GRCh38.p2

Human Diseases
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  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    43 phenotypes from multigenic genotypes
    22 phenotype references
  • All Mutations and Alleles
    9
  • Transgenic
    9
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020170 VEGA Gene Model | MGI Sequence Detail 1711 C57BL/6J ±  kb
transcript OTTMUST00000047926 VEGA | MGI Sequence Detail 686 Not Applicable  
polypeptide P14439 UniProt | EBI | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    2 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR032431 Immunoglobulin C1-set, C-terminal extension
    IPR007110 Immunoglobulin-like domain
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR014745 MHC class II, alpha/beta chain, N-terminal
    IPR001003 MHC class II, alpha chain, N-terminal
Molecular
Reagents
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  • All nucleic 63
    Genomic 52
    cDNA 6
    Primer pair 2
    Other 3

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-10383, MGD-MRK-10496, MGD-MRK-11046, MGD-MRK-11051, MGI:2146825
References
more
  • Summaries
    All 63
    Diseases 2
    Gene Ontology 4
    Phenotypes 22
  • Earliest
    J:5527 Shreffler DC, et al., The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization. Adv Immunol. 1975;20:125-95
  • Latest
    J:100678 Subramanian S, et al., Epistatic suppression of systemic lupus erythematosus: fine mapping of Sles1 to less than 1 mb. J Immunol. 2005 Jul 15;175(2):1062-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory