32 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
H2dlAb1-Ea/H2dlAb1-Ea Rag1tm1Mom/Rag1tm1Mom Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0 Tg(TRATL3A6,TRBTL3A6)#Kito/0 involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6	brain inflammation	J:189816
H2dlAb1-Ea/H2dlAb1-Ea Rag1tm1Mom/Rag1tm1Mom Tg(HLA-DRA,HLA-DRB5*0101)loKito/0 Tg(TRATL3A6,TRBTL3A6)#Kito/0 involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6	brain inflammation	J:189816
H2dlAb1-Ea/H2dlAb1-Ea Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0 involves: 129S2/SvPas * C57BL/6	normal nervous system phenotype	J:189816
H2dlAb1-Ea/H2dlAb1-Ea Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0 Tg(TRATL3A6,TRBTL3A6)#Kito/0 involves: 129S2/SvPas * C57BL/6	abnormal axon morphology	J:189816
	abnormal cytokine secretion	J:189816
	abnormal motor capabilities/coordination/movement	J:189816
	axon degeneration	J:189816
	brain inflammation	J:189816
	CNS inflammation	J:189816
	increased CD4-positive, alpha-beta T cell number	J:189816
	increased inflammatory response	J:189816
	increased interferon-gamma secretion	J:189816
	increased interleukin-17 secretion	J:189816
	increased susceptibility to experimental autoimmune encephalomyelitis	J:189816
	increased T-helper 1 cell number	J:189816
	increased T-helper 17 cell number	J:189816
	neuron degeneration	J:189816
H2dlAb1-Ea/H2dlAb1-Ea Tg(HLA-DRA,HLA-DRB5*0101)loKito/0 Tg(TRATL3A6,TRBTL3A6)#Kito/0 involves: 129S2/SvPas * C57BL/6	brain inflammation	J:189816
	increased susceptibility to experimental autoimmune encephalomyelitis	J:189816
Tg(Igk-Eik-H2-Ead)1Flv/0 Tg(Tcra1H3.1,Tcrb1H3.1)1Vire/0 involves: C57BL/6 * SJL	decreased double-positive T cell number	J:124574
	thymus hypoplasia	J:124574
Tg(Ins2-CD80)3B7Flv/0 Tg(Ins2-H2-Ead,Ins2-H2-Eb1b)187-7Bri/0 involves: C57BL/6 * CBA/Ca * SJL	abnormal pancreatic islet morphology	J:93555
	dehydration	J:93555
	increased susceptibility to autoimmune diabetes	J:93555
	insulitis	J:93555
	premature death	J:93555
	weight loss	J:93555
Tg(Ins2-CD86)12B70Flv/0 Tg(Ins2-H2-Ead,Ins2-H2-Eb1b)187-7Bri/0 involves: C57BL/6 * CBA/Ca * SJL	abnormal cytokine secretion	J:93555
	decreased pancreatic beta cell number	J:93555
	dehydration	J:93555
	increased circulating glucose level	J:93555
	increased susceptibility to autoimmune diabetes	J:93555
	insulitis	J:93555
	premature death	J:93555
	weight loss	J:93555
Tg(Ins2-H2-Ead,Ins2-H2-Eb1b)187-7Bri/0 involves: C57BL/6 * SJL	decreased insulin secretion	J:127706
	decreased susceptibility to autoimmune diabetes	J:93555
	hyperglycemia	J:127706
	increased circulating glucose level	J:93555, J:127706
	increased circulating triglyceride level	J:127706
	ketoaciduria	J:127706
	polydipsia	J:127706
	polyuria	J:127706