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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Predicted to enable MHC class II protein complex binding activity and peptide antigen binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; and positive regulation of T cell activation. Predicted to be located in membrane. Predicted to be part of MHC class II protein complex. Predicted to be active in late endosome membrane and lysosomal membrane. Human ortholog(s) of this gene implicated in Parkinson's disease (multiple); allergic disease; asthma; autoimmune thyroiditis; and multiple sclerosis. Orthologous to human HLA-DRA (major histocompatibility complex, class II, DR alpha).

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Gene Ontology Evidence Code Abbreviations:

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