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Dlx4
Gene Detail
Symbol

Name
ID
Dlx4
distal-less homeobox 4
MGI:94904
Synonyms
DII D, Dlx-4, Dlx7
Feature Type
protein coding gene
Genetic Map
Chromosome 11
59.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:95140447-95146263 bp, - strand
From VEGA annotation of GRCm38

  5817 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7292  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Gene Tree: Dlx4

Human
homologs
Human Homolog DLX4, distal-less homeobox 4
NCBI Gene ID 1748
neXtProt AC  NX_Q92988
Human Synonyms  BP1, DLX7, DLX8, DLX9
Human Chr (Location)  17q21.33; chr17:49969198-49974959 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Genomic Mutations involving Dlx4 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dlx4 interacts with 141 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process multicellular organismal development, regulation of transcription, DNA-templated
Component nucleus
Function DNA binding, sequence-specific DNA binding
External Resources: FuncBase
Expression
Literature Summary: (17 records)
Data Summary: Results (253)    Tissues (153)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 253
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) Genomic(2) cDNA(13) Primer pair(1) Other(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000001615 (Evidence)
Ensembl Gene ModelENSMUSG00000020871 (Evidence)
Entrez Gene13394 (Evidence)
UniGene439766
DFCITC1590667
DoTSDT.101132676, DT.40146010
NIA Mouse Gene IndexU033299
Consensus CDS ProjectCCDS25273.1
International Mouse Knockout Project StatusDlx4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001615 VEGA Gene Model | MGI Sequence Detail 5817 C57BL/6J ±  kb
transcript OTTMUST00000003156 VEGA | MGI Sequence Detail 2282 Not Applicable 
polypeptide OTTMUSP00000001528 VEGA | MGI Sequence Detail 240 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(73 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000047 Helix-turn-helix motif
InterPro IPR017970 Homeobox, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000006530 homeobox protein DLX-4
References
(Earliest) J:639 Robinson GW, et al., Spatially restricted expression of a member of a new family of murine Distal-less homeobox genes in the developing forebrain. New Biol. 1991 Dec;3(12):1183-94
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(51)
Other
accession IDs
MGD-MRK-38218, MGD-MRK-8860, MGD-MRK-8864, MGI:109174

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory