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Dlx4
Gene Detail
Symbol

Name
ID
Dlx4
distal-less homeobox 4
MGI:94904
Synonyms
DII D, Dlx-4, Dlx7
Feature Type
protein coding gene
Genetic Map
Chromosome 11
59.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:95140447-95146263 bp, - strand
From VEGA annotation of GRCm38

  5817 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7292  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle

HCOP human homology predictions: DLX4
Gene Tree: Dlx4

Human
homologs
DLX4, distal-less homeobox 4
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1748
neXtProt AC: NX_Q92988

Human Synonyms: BP1, DLX7, DLX8, DLX9

Human Chr (Location): 17q21.33; chr17:49969198-49974959 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Dlx4 (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dlx4 interacts with 140 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (17 records)
Data Summary: Results (253)    Tissues (153)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 253
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN dlx4a, dlx4b    NEW 
Molecular
reagents
All nucleic(19) Genomic(2) cDNA(13) Primer pair(1) Other(3)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000001615 (Evidence)
Ensembl Gene Model ENSMUSG00000020871 (Evidence)
Entrez Gene 13394 (Evidence)
UniGene 439766
DFCI TC1590667
DoTS DT.101132676, DT.40146010
NIA Mouse Gene Index U033299
Consensus CDS Project CCDS25273.1
International Mouse Phenotyping Consortium Status Dlx4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001615 VEGA Gene Model | MGI Sequence Detail 5817 C57BL/6J ±  kb
transcript OTTMUST00000003156 VEGA | MGI Sequence Detail 2282 Not Applicable 
polypeptide OTTMUSP00000001528 VEGA | MGI Sequence Detail 240 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(73 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000047 Helix-turn-helix motif
InterPro IPR017970 Homeobox, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000006530 homeobox protein DLX-4
References
(Earliest) J:639 Robinson GW, et al., Spatially restricted expression of a member of a new family of murine Distal-less homeobox genes in the developing forebrain. New Biol. 1991 Dec;3(12):1183-94
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(51)
Other
accession IDs
MGD-MRK-38218, MGD-MRK-8860, MGD-MRK-8864, MGI:109174

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory