Homozygous null mice are exhibit a steroid deficiency and die within days of birth showing signs of dehydration. Males are feminized with female external genitalia and underdeveloped gonads. Mice homozgyous for another knock-out allele exhibit abnormal adrenal development and neonatal lethality.
|Process||C21-steroid hormone biosynthetic process, cellular response to peptide hormone stimulus, ...|
|Component||membrane, mitochondrial crista, ...|
|Function||cholesterol binding, cholesterol monooxygenase (side-chain-cleaving) activity, ...|
|VEGA Gene Model||OTTMUSG00000045946 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000032323 (Evidence)|
|Entrez Gene||13070 (Evidence)|
|DoTS||DT.101724049, DT.40151364, DT.533628|
|NIA Mouse Gene Index||U010560, U010561|
|Consensus CDS Project||CCDS40653.1|
|International Mouse Phenotyping Consortium Status||Cyp11a1|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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